DEDD Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5115110

Catalog No. PIPA5115110

Description

Antibody detects endogenous levels of total DEDD.

DEDD encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: DEDD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEDD
• Gene Alias: CASP8IP1; death effector domain containing; death effector domain-containing; death effector domain-containing protein; Death effector domain-containing testicular molecule; DEDD; DEDD1; Dedpro1; DEFT; FLDED1; FLDED-1; KE05; tumor necrosis factor (ligand) superfamily, member 19
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21945, 83631, 9191
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O75618, Q9Z1L3, Q9Z2K0
• Gene Symbols: DEDD
• Immunogen: A synthesized peptide derived from human DEDD(Accession O75618), corresponding to amino acid residues P138-K188.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov