H4K20me3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA596123

Catalog No. PIPA596123

Description

Positive Samples: HeLa acid extract, NIH/3T3 acid extract, H4 protein; Cellular Location: Chromosome, Nucleus Immunogen sequence: HRKVL

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: H4K20me3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H4C1
• Gene Alias: CELE_T10C6.11, F07B7.11, F07B7.4, F45F2.12, FO108, H4, H4 histone family, member A, H4 histone family, member I, H4 histone family, member J, H4 histone family, member M, H4 histone family, member N, H4 histone, family 2, H4 K20, H4/A, H4/B, H4/C, H4/D, H4/E, H4/G, H4/H, H4/I, H4/j, H4/K, H4/M, H4/n, H4/O, H4/p, H4-12, H4-16, H4-53, H4C1, H4c11, H4C12, H4C13, H4c14, H4C15, H4C2, H4C3, H4C4, H4C5, H4c6, H4C8, H4C9, H4f16, H4F2, H4FA, H4FB, H4FC, H4FD, H4FE, H4FG, H4FH, H4FI, H4FJ, H4FK, H4FM, H4FN, H4FO, H4K20, H4Lys20me3, H4M, his-20, his-22, his-4, his-52, his-54, his-8, HIST1H4, HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, Hist1h4h, Hist1h4i, HIST1H4J, HIST1H4K, HIST1H4L, Hist1h4m, Hist2h4, HIST2H4A, HIST2H4B, Hist4h4, histone 1, H4a, histone 1, H4b, histone 1, H4e, histone 1, H4i, histone 2, H4, histone 2, H4a, Histone 4, Histone 4 family, member M, histone 4, H4, histone cluster 1, H4a, histone cluster 1, H4b, histone cluster 1, H4e, histone cluster 1, H4i, histone cluster 2, H4, histone cluster 2, H4a, Histone Cluster 4, histone cluster 4, H4, histone family member, Histone H2B 2, Histone H4, Histone H4A, Histone H4K20me3, histone IV, family 2, K06C4.12, K06C4.4, methyl Histone 3, methyl Histone H3, T10C6.11, Trimethyl H4, Tri-methyl H4, Trimethyl Histone H4, Tri-methyl Histone H4, Tri-Methyl-H4 K20, Tri-Methyl-H4 Lys20, Tri-Methyl-Histone H4 K20, Tri-Methyl-Histone H4 Lys20, X04652
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 121504, 319158, 326619, 326620, 8294, 8359, 8363, 8366, 8367, 8370, 97122
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Dot Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.17 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
• Gene Accession No.: P62805, P62806
• Gene Symbols: H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9
• Immunogen: A synthetic trimethylated peptide around K20 of human histone H4 (NP_0035291)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov