MASTL Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA584190

Catalog No. PIPA584190

Description

Immunogen sequence: EVLKTLASKR NAVAFRSFNS HINASNNSEP SRMNMTSLDA MDISCAYSGS YPMAITPTQK RRSCMPHQTP NQIKSG

MASTL or microtubule associated serine/threonine kinase-like belongs to the MAST family, AGC Ser/Thr protein kinase group. MASTL promotes mitotic progression and cell cycle reentry after DNA damage. Loss of MASTL leads to defects in chromosome condensation, separation, and other aspects of mitotic progression, which is primarily mediated by inhibiting PP2A/B55 delta. Overexpression of MASTL is correlated with cancer progression, poor patient survival, and tumor recurrence in various cancers. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.

Specifications

• Antigen: MASTL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MASTL
• Gene Alias: 2700091H24Rik, C88295, GREATWALL, greatwall kinase homolog, greatwall protein kinase, GW, GWL, hGWL, Mastl, MAST-L, microtubule associated serine/threonine kinase like, microtubule associated serine/threonine kinase-like, microtubule-associated serine/threonine-protein kinase-like, RP11-85G18.2, Serine/threonine-protein kinase greatwall, THC2
• Host Species: Rabbit
• Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84930
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
• Gene Accession No.: Q96GX5
• Gene Symbols: MASTL
• Immunogen: Recombinant protein corresponding to Human MASTL
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov