PCDH11X/PCDH11Y Polyclonal Antibody, Invitrogen™

Goat Polyclonal Antibody

Supplier:  Thermo Scientific PA5142520

Catalog No. PIPA5142520

Description

Additional Information: This antibody is expected to recognize all reported Y-linked isoforms (NP_116753.1; NP_116754.1; NP_116755.1) and all reported X-linked isoforms (NP_055337.1; NP_055337.1; NP_116750.1; NP_116751.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its most closely related cadherin superfamily member is located in this homologous region on the X chromosome. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with N- and C-terminal variation.

Specifications

• Antigen: PCDH11X/PCDH11Y
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCDH11Y
• Gene Alias: KIAA1326; PCDH11; PCDH11X; PCDH11Y; PCDH22; PCDH-PC; PCDHX; PCDH-X; PCDHY; PCDH-Y; PPP1R119; protein phosphatase 1, regulatory subunit 119; protocadherin 11 X-linked; protocadherin 11 Y-linked; protocadherin 11X; protocadherin 22; protocadherin on the X chromosome; Protocadherin on the Y chromosome; protocadherin prostate cancer; Protocadherin-11; Protocadherin-11 X-linked; protocadherin-11 Y-linked; Protocadherin-22; Protocadherin-PC; protocadherin-S
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 27328, 83259
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BZA7, Q9BZA8
• Gene Symbols: PCDH11X, PCDH11Y
• Immunogen: Peptide with sequence C-KYNWVTTPTTFK.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid