Prom1 Monoclonal Antibody (2F8C5), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA1219

Catalog No. PIMA1219

Description

MA1-219 Prom1 antibody detects Prom1 (CD133) by western blot and immunofluorescence. MA1-219 Prom1 antibody detects Prom1 by western blot at ∽130 kDa.

The CD133 (AC133) antigen is a 97 kDa glycoprotein, with 5 transmembrane domains, that shows up as a 120 kDa band on protein gels due to glycosylation. CD133 is a cell surface marker expressed by immature hematopoietic stem cells but not mature blood cells. In addition to hematopoietic stem and progenitor cells, CD133 has been found to be a marker for other stem and progenitor cells including neural and embryonic stem cells. CD133 has been shown to be expressed in cancers, including some leukemias and brain tumors, that may be derived from stem cells. Low level expression could also be detected in the kidney, pancreas, placenta, and fetal liver. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of the CD133 gene is also associated with several types of cancer. CD133 is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner, and multiple transcript variants encoding different isoforms have been found.

Specifications

• Antigen: Prom1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: O43490
• Gene Symbols: PROM1
• Immunogen: Purified recombinant fragment of human Prom1 (AA:20-108) expressed in E.Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Clone: 2F8C5
• Conjugate: Unconjugated
• Gene: PROM1
• Gene Alias: 4932416E19Rik, AC133, Antigen AC133, antigen AC133 homolog, antigen CD133, CD107b, CD133, CORD12, fudenine, hematopoietic stem cell antigen, hProminin, Lamp II, Lamp2, LAMP-2, Lamp-2a, Lamp-2b, Lamp-2c, LGP-96, LGP-B, Mac3, MCDR2, MSTP061, Prom, PROM1, Prom-1, prominin 1, prominin 1.s1, Prominin1, prominin-1, prominin-1.s2, prominin-like 1, prominin-like protein 1, PROML1, RP41, STGD4
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 8842
• Content And Storage: -20°C
• Form: Liquid