Spastin Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA553581

Catalog No. PIPA553581

Description

Immunogen sequence: KRKDPLTHTS NSLPRSKTVM KTGSAGLSGH HRAPSYSGLS MVSGVKQGSG PAPTTHKGTP KTNRTNKPST PTTATRKKKD LKNFRNVDSN LANLIMNEIV DNGTAVKFDD IAGQDLAKQA LQEIVILPSL RPELFTGL Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.

Specifications

• Antigen: Spastin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPAST
• Gene Alias: ADPSP; ATPase; fidgetin-like 1; FSP2; HAMAP-Rule:MF_03021}; hypothetical protein zgc:85952; Kiaa1083; KIAA183; LOW QUALITY PROTEIN: spastin; mKIAA1083; si:ch73-233a22.3; SPAST; spastic paraplegia 4 (autosomal dominant; spastic paraplegia 4 (autosomal dominant; spastin); spastic paraplegia 4 homolog; spastic paraplegia 4 protein; Spastin; spastin {ECO:0000255; SPG4; zgc:85952
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6683
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UBP0
• Gene Symbols: SPAST
• Immunogen: Recombinant protein corresponding to Human Spastin
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only