SPTAN1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5143594

Catalog No. PIPA5143594

Description

SPTAN1 (spectrin alpha chain, non-erythrocytic 1) is a part of the spectrin family of filamentous cytoskeletal proteins. They function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. SPTAN1 has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: SPTAN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPTAN1
• Gene Alias: (ALPHA)II-SPECTRIN; 2610027H02Rik; A2a; a--fodrin; alpha; alpha II spectrin; alpha-fodrin; alpha-II spectrin; alpha-spectrin; alpha-spectrin 2; alpha-spectrin 2, brain; brain; brain alpha-spectrin; EIEE5; FLJ44613; Fodrin alpha chain; inhibitory protein factor; IPF; NEAS; noerythroid alpha-spectrin 2; Non erythrocytic spectrin alpha; non-erythrocytic 1 (alpha-fodrin); non-erythroid alpha chain; nonerythroid alpha-spectrin; nonerythroid alpha-spectrin 2; putative alpha-spectrin; SPECA; Spectrin; Spectrin alpha; spectrin alpha chain; Spectrin alpha chain brain; spectrin alpha chain, brain; spectrin alpha chain, non-erythrocytic 1; spectrin alpha, non-erythrocytic 1; spectrin, alpha, non-erythrocytic 1; spectrin, alpha, non-erythrocytic 1 (alpha-fodrin); spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit; Spna2; Spna-2; Spta2; Sptan1
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Bovine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
• Concentration: Conc. Not Determined
• Formulation: whole serum with 5mM sodium azide
• Gene Accession No.: P16086, P16546, Q13813
• Gene Symbols: SPTAN1
• Immunogen: Recombinant constructs spanning most of human alpha-II spectrin expressed in and purified from E. coli
• Regulatory Status: RUO
• Gene ID (Entrez): 20740, 540108, 64159, 6709
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid