Human p53, Recombinant Protein, Invitrogen™

Catalog No. PIRP39232

Supplier: Thermo Scientific RP39232

Description

Recombinant Protein

p53 wild Type Recombinant Protein, RP-39232, from Invitrogen.

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons This product is a recombinant protein corresponding to full-length human p53 wild type. On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 81kDa.

Specifications

• Accession Number: P04637
• Concentration: 0.1mg/mL
• For Use With (Application): Control
• Formulation: 0.05M tris HCl with 0.01M L-glutathione and no preservative; pH 7.5
• Gene ID (Entrez): 7157
• Name: Human p53
• pH Range: 7.5
• Quantity: 10 μg
• Source: E. coli
• Storage Requirements: -20°C or -80°C if preferred
• Regulatory Status: RUO
• Gene Alias: antigen NY-CO-13, cellular tumor antigen p53, p53 tumor suppressor, phosphoprotein p53, transformation-related protein 53, TP53
• Common Name: Human p53
• Gene Symbol: TP53
• Specific Reactivity: Human
• Conjugate: Unconjugated
• Cross Reactivity: Hu
• Species: E. coli
• Recombinant: Recombinant
• Form: Liquid
• Protein Subtype: Recombinant
• Purity or Quality Grade: purified

in vitro research only.