YBX1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA513307

Catalog No. PIPA513307

Description

This antibody is predicted to react with bovine, mouse, rat and Xenopus based on sequence homology.

YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5′-CTGATTGGCCAA-3′), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.

Specifications

• Antigen: YBX1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: P67809
• Gene Symbols: YBX1
• Immunogen: KLH conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of human YBX1
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Concentration: 1.8 mg/mL
• Gene: YBX1
• Gene Alias: Nuclease-sensitive element-binding protein 1; Y-box-binding protein 1; Y-box transcription factor; YB-1; CCAAT-binding; transcription factor I subunit A; CBF-A; Enhancer factor I subunit A; EFI-A; DNA-binding protein B; DBPB; YBX1; NSEP1; YB1
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 4904
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid