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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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Heparin calcium (MW 3600-5000) is a low-molecular-weight heparin calcium salt used as an anticoagulant reagent for biochemical and pharmacological research. It forms a complex with antithrombin III to inhibit thrombin and other activated clotting factors, preventing fibrin formation. The material is a heterogeneous sulfated polysaccharide mixture provided as a dry reagent for laboratory use.
Molecular weight 3600-5000 Da
Anticoagulant activity via antithrombin III-mediated inhibition of clotting factors
Intended for biochemical and pharmacological research applications
Heterogeneous sulfated polysaccharide mixture, not a single defined molecule
Supplied as a dry reagent suitable for in vitro assays
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
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Beta-Lapachone (CAS 4707-32-8) is a small molecule inhibitor of DNA topoisomerase I In DNA unwinding assays beta-Lapachone suppresses topoisomerase I-mediated DNA relaxation at concentrations as low as 1 M without inhibiting topoisomerase II or inducing topoisomerase I-dependent DNA cleavage It exhibits broad cytotoxicity against human cancer cell lines such as AD2780s HT-29 DLD G480 and MCF-7 with IC50 values ranging from 2 to 5 M The compound induces cell death through cytochrome c release triggering both apoptosis and necrosis and affects cell cycle progression causing S-phase and G2/M arrest in different carcinoma cell models Beta-Lapachone is widely utilized in studies investigating topoisomerase I inhibition cancer cell cytotoxicity and cell cycle regulation
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