Carbohydrates
Apexbio Technology LLC Methyl α-D-mannopyranoside 617-04-9 5g
Methyl alpha-D-mannopyranoside (CAS 617-04-9) is a small-molecule ligand targeting mannose receptors expressed on macrophages It is designed to bind selectively to these receptors thereby facilitating internalization and intracellular delivery of conjugated therapeutic agents Methyl alpha-D-mannopyranoside exerts its biological activity primarily through specific binding to macrophage mannose receptors enabling targeted transport into macrophages Studies evaluating receptor binding report IC50 values generally ranging from micromolar to millimolar levels depending on experimental conditions and assay methods Based on these pharmacological properties methyl alpha-D-mannopyranoside holds research potential in targeted drug delivery for anti-tubercular therapies
Medchemexpress LLC D(+)-Trehalose dihydrate | 6138-23-4 | 378.3 g/mol | 5 G
D-(+)-Trehalose dihydrate is an orally active disaccharide that exhibits anti-desiccant and cryopreservative activities. It functions as an osmolyte and stress protectant, aiding in carbon storage and transport. This product can be utilized as a food ingredient and pharmaceutical excipient.
- Orally active disaccharide
- Anti-desiccant activity
- Cryopreservative activity
- Acts as an osmolyte
- Stress protectant
- Aids in carbon storage and transport
- Suitable for use as a food ingredient
- Suitable for use as a pharmaceutical excipient
Medchemexpress LLC KVA-D-88 | 2410550-31-9 | 99.8% | 382.19 | C17H11Cl2F2N3O | 5 MG
KVA-D-88 is a small-molecule, selective phosphodiesterase 4B (PDE4B) inhibitor supplied for research use in pharmacology and neuroscience studies. It has been used in vivo to investigate modulation of reward-related behaviors and cAMP signaling pathways.
- Selective inhibition of PDE4B, useful for target-specific studies.
- High chemical purity suitable for research assays.
- Powder form facilitates formulation and dosing flexibility.
- Stable under recommended low-temperature storage conditions.
- Reported molecular weight and formula available for analytical confirmation.
Medchemexpress LLC d-KLA Peptide | 286380-05-0 | 99.3% | 1523.99 | 5 MG
d-KLA Peptide is a synthetic pro-apoptotic peptide that specifically targets mitochondria and induces apoptosis by destroying the mitochondrial membrane. It activates biochemical pathways associated with apoptosis, including the activation of caspase family proteins and PARP (poly ADP ribose polymerase). d-KLA Peptide can also be used to carry and deliver genes or small molecules to enhance anti-tumor effects.
- Synthetic pro-apoptotic peptide
- Specifically targets mitochondria
- Induces apoptosis by destroying the mitochondrial membrane
- Activates caspase family proteins
- Activates PARP (poly ADP ribose polymerase)
- Can be used to carry and deliver genes or small molecules
- Enhances anti-tumor effects
![Alkali Scientific Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 10 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659788.jpg-250.jpg)
Alkali Scientific Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 10 Kg
Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 250g, is a high-quality reagent commonly used in biochemical, molecular biology, and analytical research. This ultra-pure form of Tris Base ensures low levels of impurities, making it ideal for sensitive applications such as electrophoresis, protein analysis, and enzyme reactions. The 250g size is suitable for smaller laboratories or for preparing smaller volumes of Tris-buffered solutions. Tris is essential for stabilizing the pH of reaction mixtures, making it widely used in buffer formulations and for preparing buffers in protein and nucleic acid research. It is an essential reagent for various applications requiring precise pH control.
Apexbio Technology LLC Inosine 58-63-9 10mM (in 1mL DMSO)
Inosine (58-63-9) is an endogenous purine nucleoside It participates in purine catabolic and salvage pathways facilitating nucleotide synthesis and uric acid formation Inosine is structurally composed of hypoxanthine linked to a ribose sugar moiety It is also present in specific tRNA anticodons influencing translational processes Inosine exerts its biological activity by serving as an intermediate in purine metabolism and modulating nucleotide recycling and tRNA modifications In biochemical and cell biology studies inosine is utilized as a tool compound to investigate purine metabolism nucleotide recycling pathways tRNA modifications receptor-mediated signaling and immune regulation in vitro Reported IC50 values may vary depending on biological models and experimental conditions applied Based on these pharmacological properties inosine holds research potential in studies of purine metabolism nucleotide synthesis RNA biology and immune regulation
Selleck Chemical LLC Iron sucrose S3729-100mg
Iron sucrose (Iron saccharate Sucroferric oxyhydroxide) is an intravenously administered iron product indicated in the treatment of iron deficiency anemia
Medchemexpress LLC Sucrose hexasulfate potassium salt | 386229-70-5 | MFCD00270079 | >98.0% | 1051.2 g·mol⁻¹ | C12H16K6O29S6 | 5 MG
Sucrose hexasulfate potassium is the hexapotassium salt of sucrose hexasulfate used as a biochemical reagent and reference standard in glycobiology and pharmaceutical research. It is supplied in small, high-purity quantities for analytical, reference, and assay applications.
- Hexapotassium sulfated disaccharide suitable for glycobiology studies.
- High purity for use as a reference standard (>98%).
- Suitable for analytical and assay development applications.
- Provided in small pack sizes appropriate for research use.
- Water-soluble salt form for convenient preparation of aqueous solutions.
Medchemexpress LLC a-D-Galactose pentaa 50g
-D-Galactose pentaacetate (Pentaacetyl- -D-galactopyranose) is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC CHMFL-PI4K-127 | 2377604-81-2 | C18H15ClN4O3S | 100 MG
CHMFL-PI4K-127 (compound 15g) is an orally active, potent, and highly selective PfPI4K (Plasmodium falciparum PI4K kinase) inhibitor with an IC50 of 0.9 nM. It demonstrates potent activity against 3D7 Plasmodium falciparum, exhibiting an EC50 of 25.1 nM. This compound shows antimalaria efficacy, displaying high selectivity against PfPI4K over human lipid and protein kinases. In vivo studies in rodent models demonstrated significant antimalarial activities in a dose-dependent manner, generating curative effects in the blood stage at 80 mg/kg and full protection in the liver stage at 1 mg/kg.
- Potent and highly selective PfPI4K inhibitor
- Orally active
- Shows antimalaria efficacy
- High selectivity against PfPI4K over human lipid and protein kinases
- Significant antimalarial activities in rodent models
Medchemexpress LLC D-(+)-Phenyllactic acid | 7326-19-4 | 99.9% | 166.18 | 1 ML
D-(+)-Phenyllactic acid is an antibacterial agent excreted by Geotrichum candidum. It inhibits a range of Gram-positive and Gram-negative bacteria found in humans and foodstuffs. This product is for research use only and not sold to patients.
- Inhibits Mcl-1 and Bim interaction with an IC50 of 0.161 μM.
- Inhibits cell viability of SKBR-3 with an EC50 of 112.69 nM.
- Exhibits broad-spectrum antibacterial effect against L. monocytogenes, S. aureus, E. faecalis, and K. oxytoca.
- White to off-white solid.
- Soluble in DMSO and H₂O.
Medchemexpress LLC Bonducellpin D | 197781-85-4 | 1 MG
Bonducellpin D is a furanoditerpenoid lactone isolated from Caesalpinia minax. It demonstrates broad-spectrum inhibition against SARS-CoV Mpro and MERS-CoV Mpro, with Ki values of 467.11 nM and 284.86 nM, respectively. This compound also exhibits moderate anti-cancer activity in vitro.
- Isolated from Caesalpinia minax
- Demonstrates broad-spectrum inhibition potential against SARS-CoV Mpro
- Inhibits MERS-CoV Mpro
- Exhibits moderate anti-cancer activity in vitro
Medchemexpress LLC 5-bromo-6-chloro-3-indolyl β-D-glucuronide cyclohexylammonium | 144110-43-0 | MFCD00153929 | 99.8% | 521.79 | C20H26BrClN2O7 | 5 MG
Magenta-β-D-GlcA (5-Bromo-6-chloro-3-indolyl β-D-glucuronide cyclohexylammonium) is a chromogenic biochemical reagent used as a substrate for β-glucuronidase assays. Upon enzymatic hydrolysis it produces a magenta-colored indoxyl product, enabling visual detection and histochemical staining in biochemical and microbiological applications. The compound is supplied as a high-purity solid in multiple pack sizes.
- Chromogenic substrate for β-glucuronidase assays.
- Produces a magenta-colored product for visual detection.
- High purity: 99.79%.
- Suitable for histochemical staining and enzyme activity assays.
- Available in multiple pack sizes for small- to larger-scale work.
Apexbio Technology LLC Iron sucrose 8047-67-4 100mg
Iron sucrose (CAS 8047-67-4) is a complex of polynuclear iron(III)-hydroxide with sucrose used as an intravenous iron supplement It delivers bioavailable iron which is incorporated into ferritin and hemoglobin following endocytosis and intracellular processing Unlike iron dextran iron sucrose is associated with a lower incidence of hypersensitivity reactions and is frequently used to manage iron deficiency anemia in chronic kidney disease both in patients undergoing dialysis and those who are not It is widely utilized in preclinical and clinical research to study iron metabolism erythropoiesis and anemia associated with renal disorders
Medchemexpress LLC L-Inosine | 21138-24-9 | 99.9% | 268.23 | 50 MG
L-Inosine is the L-configuration of Inosine. It is an endogenous purine nucleoside produced by the catabolism of adenosine. It exhibits anti-inflammatory, antinociceptive, immunomodulatory, and neuroprotective effects.
- L-configuration of inosine
- Endogenous purine nucleoside
- Produced by the catabolism of adenosine
- Exhibits anti-inflammatory effects
- Exhibits antinociceptive effects
- Exhibits immunomodulatory effects
- Exhibits neuroprotective effects
- Solid, white to off-white appearance
- Melting/freezing point of 218°C
- For research use only