Lipids and Lipid Derivatives
Medchemexpress LLC N-acetyl-D-erythro-sphingosine | 3102-57-6 | MFCD00153903 | 99.9% | 341.53 g·mol⁻¹ | C20H39NO3 | 100 MG
C2 ceramide (N-acetyl-D-erythro-sphingosine, CAS 3102-57-6) is a short-chain ceramide used in cellular and biochemical research. It functions as a protein phosphatase activator and modulates signaling pathways involved in differentiation, autophagy, and apoptosis. Supplied as a solid suitable for dissolution in organic solvents.
- Activates protein phosphatases involved in cell regulation.
- Modulates differentiation, autophagy, and apoptosis.
- Inhibits mitochondrial respiratory complex III in some studies.
- Acts as a skin-conditioning agent that supports epidermal barrier function.
- High purity suitable for research applications.
Cambridge Isotope Laboratories Lyso-PC 24 0 (unlabeled) CP 95% 0 01 g
Lyso-PC 24 0 (unlabeled) CP 95% 0 01 g
![Medchemexpress LLC Octanamide, N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]- | 158983-53-0 | 99.0% | 505.67 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000391444.png-250.jpg)
Medchemexpress LLC Octanamide, N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]- | 158983-53-0 | 99.0% | 505.67 | 5 MG
C-8 Ceramide-1-phosphate is a chemical compound primarily identified for its role in cellular processes. It functions as an inhibitor of cell apoptosis and an inducer of cell survival.
- Inhibits cell apoptosis
- Induces cell survival
- Available in an off-white to light yellow solid form
- High purity of 99.0%
- Stable storage conditions for powder and in solvent
Medchemexpress LLC C16-ceramide | 24696-26-2 | MFCD00056205 | ≥99.0% | 537.90 | C34H67NO3 | 5 MG
C16-ceramide is a natural ceramide lipid reagent used in cell biology research. It binds directly and selectively to p53 to activate p53 signaling, can induce apoptosis in certain cell lines, and is used to probe ceramide-mediated regulatory pathways. Provided as solid material and as solution formulations for assay compatibility.
- Direct activation of p53 through selective binding.
- Induces apoptosis in p53-related cellular assays.
- High purity (≥99.0%) suitable for research use.
- Available as solid and solution formats for flexibility.
- Stable when stored protected from light at recommended temperatures.
Medchemexpress LLC N-Hexanoylsphingosine | 124753-97-5 | 99.8% | 397.63 | 100 MG
C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator exhibiting significant anticancer activity. It plays a role in mediating miR-29b expression, which is involved in suppressing the progression of multiple myeloma by targeting the Akt signal pathway. This compound demonstrates a range of anti-cancer properties and can enhance the effects of chemotherapy in drug-resistant cancer cells.
- Short-chain, cell-permeable ceramide pathway activator
- Possesses anticancer activity
- Mediates miR-29b expression
- Suppresses proliferation, migration, and angiogenesis of endothelial cells
- Targets the Akt signal pathway
- Induces cell cycle arrest and apoptosis
- Inhibits tumor growth
- Enhances chemotherapy effects in drug-resistant cancer cells
- Useful as an adjuvant for chemotherapeutic agents
Cayman Chemical C12 NBD dihydro Ceramide d18
A fluorescent ceramide analog that contains a saturated bond in the C-4/C-5 position of the sphingosine backbone
Medchemexpress LLC Sphingomyelin Syntha 50ug
The sphingomyelin synthase 2 (SGMS2) protein plays a crucial role in plasma membrane sphingomyelin synthesis It catalyzes the reversible transfer of the phosphocholine moiety in sphingomyelin biosynthesis to form ceramide phosphocholine Sphingomyelin Synthase 2/SGMS2 Protein Human (HEK293 Fc) is the recombinant human-derived Sphingomyelin Synthase 2/SGMS2 protein expressed by HEK293 with N-mFc labeled tag
Cayman Chemical W-azIdo-C6 CeramIde 10mg
A clickable form of C6 ceramide; active against N. meningitidis and N. gonorrhoeae (MIC = 2 UG/ml for both); has been used to conjugate alkynylated fluorescent probes to liposomes containing ω-azido-C6 ceramide via a click reaction
Medchemexpress LLC Sphingomyelin | 85187-10-6 | ≥99.0% | 100 MG
Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann-Pick disease.
- In vitro: Sphingomyelin metabolism results in the production of various interconvertible bioactive sphingolipids or derivatives such as ceramide, diacylglyceride, and sphingosine-1-phosphate. These bioactive lipids act on their specific targets within the cell and regulate various signal transduction pathways, thereby affecting cellular functions. Sphingomyelin enriched lipid raft mediated cell signaling.
Medchemexpress LLC Sphingomyelin | 85187-10-6 | ≥99.0% | 493.6 g/mol | 25 MG
Sphingomyelin is a eukaryotic sphingolipid that is a major constituent of cell membranes and is particularly abundant in the myelin sheath that surrounds neuronal axons. It plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann-Pick disease.
- Endogenous metabolite
- Plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction.
- Metabolism is associated with various central nervous system diseases and Niemann-Pick disease.
Medchemexpress LLC 4,7,10,13,16,19-Docosahexaenamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen -1-yl]- | 218608-43-6 | 98.7% | 609.96 | 25 MG
DHA Ceramide is a light yellow to yellow solid with a molecular weight of 609.96. It has a purity of 98.65% by HPLC and is tested to comply with given specifications. This product is for research use only.
- Light yellow to yellow solid
- For research use only
- Store at -20°C, protected from light, and under nitrogen
- Tested and complies with given specifications
Cayman Chemical C162 S-hydroxy CeramIde 10mg
A synthetic ceramide; has no effect on C6 glioma cell viability at concentrations up to 20 µM