Lipids and Lipid Derivatives
Medchemexpress LLC Estradiol 17-(β-D-glucuronide) sodium | 15087-02-2 | MFCD00056557 | 99.5% | C24H31NaO8 | 10MG
Estradiol 17-(β-D-glucuronide) sodium is the sodium salt of a conjugated estrogen (E217G) formed in the liver and excreted in bile. It is used as a research reagent to investigate estrogen metabolism, transporter activity, and mechanisms of cholestasis. Supplied as a high-purity solid for in vitro and biochemical assays; for research use only.
- High purity suitable for analytical and biochemical assays.
- Serves as a substrate for hepatic transporters involved in bile excretion.
- Relevant for studying intrahepatic cholestasis and estrogen metabolism.
- Soluble in polar organic solvents such as DMSO and DMF.
- Available in multiple small-scale pack sizes for lab use.
Medchemexpress LLC Alpha-Estradiol (Standard) | 57-91-0 | 99.9% | 50 MG
Alpha-Estradiol (Standard) is the analytical standard of Alpha-Estradiol, intended for research and analytical applications. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor used as a topical medication in the treatment of androgenic alopecia.
- Analytical standard for research and analytical applications
- Used in HPLC, GC, and MS experiments
- Weak estrogen and 5α-reductase inhibitor
- Solid appearance, white to off-white
- Stable under recommended storage conditions
Apexbio Technology LLC Estradiol Cypionate 313-06-4 1g
Estradiol cypionate (313-06-4) is a small-molecule agonist targeting estrogen receptors (ER) It is designed to activate ER thereby modulating downstream ER-mediated gene transcription and signaling pathways and regulating processes such as vascular homeostasis Estradiol cypionate exerts its biological activity primarily through ER agonism influencing gene expression and inhibiting endothelin-1 (ET-1) synthesis via ER-dependent mechanisms Based on these pharmacological properties estradiol cypionate holds research potential in elucidating estrogen receptor mechanisms and studying estrogen-associated vascular and endocrine systems and disorders
Cayman Chemical 2-bromo 17-EstradIol 10mg
A synthetic steroid and inhibitor of estrogen 2-hydroxylase; inhibits estrogen 2-hydroxylase in rat liver microsomes at 50 and 100 µM; prevents estrogen-induced inhibition of apomorphine-induced climbing behavior in mice at 5 mg/kg
Medchemexpress LLC Estradiol 17-(β-D-glucuronide) (sodium) | 15087-02-2 | 98.9% | 25 MG
Estradiol 17-(β-D-Glucuronide) sodium is a D-ring glucuronide metabolite of natural estrogen formed in the liver. It acts as a substrate for the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). This compound regulates MRP8-mediated transport processes and is suitable for studies related to intrahepatic cholestasis.
- D-ring glucuronide metabolite of natural estrogen
- Substrate for organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2)
- Regulates MRP8-mediated transport processes
- Inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid
- Induces immediate, reversible reduction of bile flow
- Suitable for studies related to intrahepatic cholestasis
Medchemexpress LLC Alpha-Estradiol | 57-91-0 | MFCD00064144 | 99.9% | 500 MG
Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.
- Acts as a weak estrogen
- Functions as a 5α-reductase inhibitor
- Suitable for topical medication in the treatment of androgenic alopecia
- Purity of 99.88%
- Inhibits testosterone metabolism
- Attenuates LPS-induced inflammatory markers
- Decreases malondialdehyde (MDA) levels
Medchemexpress LLC Estradiol 3-methyl ether | 1035-77-4 | 99.9% | 286.41 | 5 MG
Estradiol 3-methyl ether, also known as 3-O-Methyl estradiol, is a synthetic estrogen. This compound has demonstrated the ability to disrupt microtubule networks in V79 cells with an EC50 of 9 μM, and it also inhibits cell proliferation. Furthermore, Estradiol 3-methyl ether has been observed to decrease serum cholesterol levels and contribute to body weight loss, indicating feminizing activity in an HFD murine model. It is intended for research use only.
- Functions as a synthetic version of the hormone estrogen.
- Can disrupt microtubule networks in V79 cells with an EC50 of 9 μM.
- Inhibits the proliferation of cells.
- Decreases serum cholesterol levels.
- Leads to an increase in body weight loss in HFD murine models.
- Exhibits feminizing activity in HFD murine models.
Medchemexpress LLC Estradiol dipropionate | 113-38-2 | 99.5% | 100 MG
Estradiol dipropionate is a combined estrogen-progesterone, acting as an estrogen and progesterone agonist. It is intended for research use only.
- Purity: 99.5%
- Molecular weight: 384.51
- Formula: C24H32O4
- Appearance: White to off-white solid
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years
- Recommended storage for in solvent: -80°C for 2 years, -20°C for 1 year
- Shipping at room temperature is acceptable if less than 2 weeks
Medchemexpress LLC Estradiol 17-(β-D)-glucuronide | 1806-98-0 | MFCD00198971 | 99.0% | 448.51 g/mol | C24H32O8 | 1 MG
Estradiol 17-(β-D)-glucuronide is a glucuronidated metabolite of the estrogen estradiol used as a research reagent. It functions as a cholestatic agent and a high-affinity substrate for OATP organic anion transporters, and is commonly applied in studies of hepatic transport, bile acid homeostasis, and estrogen metabolism.
- Used as a cholestatic agent in in vitro and in vivo studies.
- High-affinity substrate for OATP organic anion transporters.
- Provided as a high-purity research-grade compound (purity 99.0%).
- Supplied in milligram quantities suitable for biochemical assays.
- Molecular formula C24H32O8; molecular weight 448.51 g/mol.
Medchemexpress LLC Estradiol 3-methyl ether | 1035-77-4 | 99.9% | 286.41 | 50 MG
Estradiol 3-methyl ether is a synthetic estrogen. It can disrupt microtubule networks in V79 cells with an EC50 of 9 μM, and it also inhibits cell proliferation. Additionally, Estradiol 3-methyl ether has been shown to decrease serum cholesterol levels and increase body weight loss, indicating feminizing activity in an HFD murine model.
- Synthetic estrogen
- Disrupts microtubule networks in V79 cells with an EC50 of 9 μM
- Inhibits cell proliferation
- Decreases serum cholesterol levels in HFD murine model
- Increases body weight loss in HFD murine model
- Indicates feminizing activity in HFD murine model
Apexbio Technology LLC Estradiol 50-28-2 10mM (in 1mL DMSO)
Estradiol is an endogenous steroid hormone involved in the regulation of reproductive biology and cellular physiology through interaction with estrogen receptor (ER) subtypes and Estradiol binding to ER initiates genomic and non-genomic signaling pathways influencing transcription of diverse target genes related to proliferation differentiation and metabolism Estradiol-mediated ER signaling modulates cellular processes including epithelial-mesenchymal transition endothelial function oxidative stress responses and gene expression profiles in various cell lines such as HEK293 and U2OS Additionally estradiol treatment regulates cardiovascular function by inducing mitochondrial superoxide dismutase (SOD2) implicating protective effects in vascular conditions Estradiol exhibits ER subtype selectivity with reported ER and ER binding affinities (IC50) around 0 2-0 5 nM utilized broadly in estrogen signaling research and cardiovascular disease modelling
Medchemexpress LLC β-estradiol-6-one 6-(O-carboxymethyloxime) | 35048-47-6 | MFCD00056459 | 99.7% | 359.42 g/mol | C20H25NO5 | 5 MG
β-Estradiol-6-one 6-(O-carboxymethyloxime) is an estradiol-derived small molecule functionalized at the 6-position with an O-carboxymethyloxime moiety. It is used as an alkyl chain-based PROTAC linker and building block for synthesizing targeted protein degradation constructs. Provided for research use only.
- Designed as an alkyl chain-based PROTAC linker for conjugation chemistry.
- High purity suitable for analytical and synthetic applications.
- Solid form, easy to handle and store.
- Molecular formula C20H25NO5 and molecular weight 359.42 g/mol.
- Available in small pack sizes for research and method development.
Cayman Chemical Ethynyl Estradiol
An estrogen receptor agonist (EC50 = 8.5 pM in a reporter assay using T47D cells); reduces serum cholesterol levels and femur bone mass and increases uterine mass in an OVX rat model of postmenopause at 0.1 mg/kg per day; has been found in wastewater effluent; prevents secondary sexual development in male fathead minnows and increases the numbers of intersex fish at 4 ng/l
Selleck Chemical LLC Estradiol Cypionate S4046-50mg
Estradiol cypionate is the 17 -cyclopentylpropinate ester of estradiol which inhibits ET-1 synthesis via estrogen receptor
Sigma Aldrich Fine Chemicals Biosciences 17alpha-Ethynylestradiol >=98% | 57-63-6 | MFCD00003690 | 1G
17alpha-Ethynylestradiol >=98% | Purity: >=98% | Mol Wt: 296.4 | 57-63-6 | MFCD00003690 | 1G
