Lipids and Lipid Derivatives
Selleck Chemical LLC Ethinyl Estradiol S1625-50mg
Ethinyl Estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills
Medchemexpress LLC β-estradiol-6-one 6-(O-carboxymethyloxime) | 35048-47-6 | MFCD00056459 | 99.7% | 359.42 g/mol | C20H25NO5 | 5 MG
β-Estradiol-6-one 6-(O-carboxymethyloxime) is an estradiol-derived small molecule functionalized at the 6-position with an O-carboxymethyloxime moiety. It is used as an alkyl chain-based PROTAC linker and building block for synthesizing targeted protein degradation constructs. Provided for research use only.
- Designed as an alkyl chain-based PROTAC linker for conjugation chemistry.
- High purity suitable for analytical and synthetic applications.
- Solid form, easy to handle and store.
- Molecular formula C20H25NO5 and molecular weight 359.42 g/mol.
- Available in small pack sizes for research and method development.
Cayman Chemical Ethynyl Estradiol, Purity: ≥98%, CAS: 57-63-6, 5 g
An estrogen receptor agonist (EC50 = 8.5 pM in a reporter assay using T47D cells); reduces serum cholesterol levels and femur bone mass and increases uterine mass in an OVX rat model of postmenopause at 0.1 mg/kg per day; has been found in wastewater effluent; prevents secondary sexual development in male fathead minnows and increases the numbers of intersex fish at 4 ng/l
Apexbio Technology LLC Mifepristone, 100mg. Cas: 84371-65-3 MFCD: MFCD00867226. Progesterone receptor antagonist
Mifepristone (RU486) is a potent antagonist of progesterone receptor, used as a contraceptive agent. 84371-65-3. MFCD00867226
Apexbio Technology LLC Cyproterone Acetate 427-51-0 250mg
Cyproterone Acetate (CAS 427-51-0) is a small-molecule antagonist targeting the androgen receptor (AR) It is designed to inhibit AR activation thereby suppressing androgen-mediated cellular signaling Cyproterone Acetate exerts its biological activity primarily through competitive binding to AR displacing endogenous androgen ligands and blocking receptor activation and downstream signaling In experimental assays Cyproterone Acetate demonstrates AR inhibition with an IC50 value of approximately 7 1 nM At higher concentrations (EC50 around 4 0 M) it may also exhibit partial agonist activity on the AR pathway Based on these pharmacological properties Cyproterone Acetate holds research potential in studies of androgen-dependent biological processes AR signaling mechanisms and hormone-sensitive pathologies such as prostate cancer or androgen-related metabolic conditions
Apexbio Technology LLC Hydrocortisone(Synonyms: Cortisol, 17-Hydroxycorticosterone, Kendall's Compound F), 1g, CAS: 50-23-7.
Hydrocortisone (CAS 50-23-7) is an endogenous glucocorticoid primarily synthesized and secreted by the adrenal cortex It exerts biological effects by binding glucocorticoid receptors altering gene expression involved in metabolic regulation immune response modulation and anti-inflammatory pathways Widely utilized in biomedical research hydrocortisone serves as a standard reference agent for investigating glucocorticoid receptor signaling inflammation models and stress response mechanisms
TARGETMOL CHEMICALS INC HYDROCORTISONE ACEPONATE 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is an effective topical glucocorticoid used in the form of a cream to treat various skin diseases. purity: 99%
Medchemexpress LLC Cortisone acetate | 50-04-4 | 98.9% | 402.48 | 10 G
Cortisone acetate (Cortisone 21-acetate) is an oxidized metabolite of Cortisol (a Glucocorticoid). It functions as an immunosuppressant and anti-inflammatory agent. Cortisone acetate can partially intervene in the binding of Glucocorticoid to the Glucocorticoid-receptor at high concentrations.
- Acts as an immunosuppressant and anti-inflammatory agent
- Can partially intervene in the binding of Glucocorticoid to Glucocorticoid-receptor
Medchemexpress LLC Hydrocortisone cypionate | 508-99-6 | 486.64 | 1 ML
Hydrocortisone cypionate | 508-99-6 | 486.64 | 1 ML
Medchemexpress LLC Cortisone | 53-06-5 | 99.3% | 360.44 | 1 ML
Cortisone (17-Hydroxy-11-dehydrocorticosterone) is an oxidized metabolite of Cortisol, a Glucocorticoid. It functions as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in the binding of Glucocorticoid to the Glucocorticoid-receptor at high concentrations, and has been shown to attenuate apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs) and decrease BCG lesions and tuberculin reactions in rabbits.
- Acts as an immunosuppressant
- Acts as an anti-inflammatory agent
- Attenuates apoptosis
- Decreases BCG lesions and tuberculin reactions
- Targets Glucocorticoid Receptor
- Is an endogenous metabolite
Medchemexpress LLC Hydrocortisone (Standard) | 50-23-7 | 362.46 | 100 MG
Hydrocortisone (Standard) is the analytical standard of Hydrocortisone. This product is intended for research and analytical applications. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
- Analytical standard
- Intended for research and analytical applications
- Used as a reference standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
- Steroid hormone or glucocorticoid secreted by the adrenal cortex
Apexbio Technology LLC Cortisone acetate 50-04-4 10mM (in 1mL DMSO)
Cortisone acetate (50-04-4) is a glucocorticoid receptor agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid signaling thereby regulating gene transcription and downstream immune and inflammatory responses Cortisone acetate exerts its biological activity primarily through enzymatic conversion to cortisol which subsequently activates glucocorticoid receptors to influence cellular stress and inflammatory pathways Based on these pharmacological properties cortisone acetate holds research potential in the investigation of glucocorticoid signaling pathways receptor-mediated transcriptional regulation cellular stress responses and inflammatory condition models