Nucleosides and Analogues
![Medchemexpress LLC 1-[3-(difluoromethyl)-1,2-thiazol-5-yl]-3-[2-fluoro-5-(hydroxymethyl)-4-pyridinyl]urea | 2270879-17-7 | 99.7% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234159.png-250.jpg)
Medchemexpress LLC 1-[3-(difluoromethyl)-1,2-thiazol-5-yl]-3-[2-fluoro-5-(hydroxymethyl)-4-pyridinyl]urea | 2270879-17-7 | 99.7% | 1 ML
BRM/BRG1 ATP Inhibitor-1 is an orally active, allosteric small-molecule inhibitor of the chromatin-remodeling ATPases BRM (SMARCA2) and BRG1 (SMARCA4), supplied for research use. It is offered as a white to off-white solid and as a 10 mM solution in DMSO (1 mL), and it shows low-nanomolar potency in biochemical assays (IC50 <5 nM).
- Allosteric dual inhibitor of BRM and BRG1.
- Molecular formula C11H9F3N4O2S, molecular weight ≈318.3 g/mol.
- High reported purity for research applications.
- Available as a solid and as a 10 mM DMSO solution (1 mL).
- Recommended solvent: DMSO; prepare stock solutions and store at -80°C or -20°C per stability guidance.
Medchemexpress LLC Uridine 5'-monophosphate-d11 dilithium | 00-00-0 | 99.9% | 347.12 g/mol | C9D11Li2N2O9P | 1 MG
Uridine 5'-monophosphate-d11 dilithium is a deuterium-labeled nucleotide provided as the dilithium salt for use as an internal standard or tracer in analytical and metabolic studies. It is intended for precise mass-spectrometry quantification and research applications; store frozen for stability.
- Deuterium-labeled analogue for mass spectrometry tracing.
- Dilithium salt form for improved handling and solubility.
- High chemical purity (99.9%).
- Supplied as a research-grade micro quantity (1 mg).
- Stable when stored at -20°C for up to 2 years.
- Suitable as an internal standard in LC-MS/MS workflows.
Medchemexpress LLC 2′-deoxyguanosine 5′-monophosphate-d12 dilithium | 98.8% | 371.16 g/mol | C10D12Li2N5O7P | 1 MG
2′-Deoxyguanosine 5′-monophosphate-d12 dilithium is a deuterium-labeled deoxyribonucleotide provided as the dilithium salt for research use. It serves as an isotopically labeled standard for spectroscopic analyses and tracing experiments, offering reliable, high-purity material for analytical workflows.
- Deuterium-labeled dGMP (d12) suitable for NMR and mass spectrometry.
- Supplied as the dilithium salt for improved solubility and handling.
- High purity (98.8%) for analytical confidence.
- Molecular formula C10D12Li2N5O7P; molecular weight 371.16 g/mol.
- Available in 1 mg vials; recommended formulation: 100 mM in 26.94 μL Tris HCl/D2O buffer pH 7.5.
- Datasheet, certificate of analysis, and safety data sheet available.
Medchemexpress LLC a-D-Glucosamine pent 10g | 7784-54-5 | 10 G
Alpha-D-glucosamine pentaacetate is the fully acetylated derivative of D-glucosamine used as an intermediate and reagent in glycobiology and carbohydrate chemistry. It is supplied as a solid for synthetic and analytical workflows, including derivatization and glycan synthesis.
- Fully acetylated amino sugar derivative for carbohydrate synthesis.
- High purity suitable for research (≥97.0%).
- Useful as a synthetic intermediate and for glycobiology studies.
- Solid form for convenient storage and handling.
- Molecular formula C16H23NO10; molecular weight 389.35 g·mol⁻¹; CAS 7784-54-5.
Medchemexpress LLC Cytarabine triphosph 25mg | 1179343-17-9 | 25 MG
Cytarabine triphosphate trisodium is the trisodium salt of cytarabine triphosphate and is used as a research reagent to study DNA synthesis inhibition and nucleoside metabolism.
- Trisodium salt form supplied as a solution.
- Pack size 25 mg, prepared as 100 mM x 500 μL in water for the 25 mg vial.
- Molecular formula C9H13N3Na3O14P3 and molecular weight 549.10 g/mol.
- Purity approximately 96.8%.
- Storage: solution at -20°C; prepared stock solution stability: -80°C for 6 months, -20°C for 1 month.
- Used as the active metabolite Ara-CTP in biochemical and cell-based assays targeting DNA synthesis.
Medchemexpress LLC Motesanib diphosphate | 857876-30-3 | MFCD12407403 | 99.9% | 569.44 g/mol | C22H29N5O9P2 | 5 MG
Motesanib diphosphate is the diphosphate salt of motesanib, an ATP-competitive inhibitor of VEGFR1/2/3 and c-Kit, supplied for laboratory research and analytical applications.
- Potent ATP-competitive inhibitor of VEGFR1/2/3 and c-Kit.
- Molecular formula: C22H29N5O9P2.
- Molecular weight: 569.44 g/mol.
- Pack size: 5 mg.
- Solubility: DMSO ≥ 110 mg/mL; H2O 5 mg/mL (with ultrasonic warming).
- Storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
- For research use only; not for human or veterinary use.
Medchemexpress LLC Nicotinamide riboside chloride | 23111-00-4 | MFCD27952781 | 100.0% | 290.70 | C11H15ClN2O5 | 5MG
Nicotinamide riboside chloride (standard) is an analytical standard of nicotinamide riboside chloride used for research and analytical applications. It is a high-purity NAD+ precursor and source of vitamin B3, supplied as a solid for quantitation, method validation, and metabolic studies.
- High purity suitable for analytical and research use.
- Available in multiple small sizes for use as standards.
- CAS 23111-00-4 provides unambiguous compound identification.
- Molecular weight and formula provided for accurate calculations.
- Applicable in studies of NAD+ metabolism and sirtuin activation.
Medchemexpress LLC Adenosine N1-oxide | 146-92-9 | MFCD00037993 | 99.5% | 283.24 g/mol | C10H13N5O5 | 10 MG
Adenosine N1-oxide is an adenosine derivative used in research with reported oral anti-inflammatory activity. Isolated from royal jelly, it has been reported to promote osteogenic and adipocyte differentiation and is supplied as a purified solid for laboratory studies.
- Oral active anti-inflammatory agent.
- Promotes osteogenic and adipocyte differentiation.
- Molecular formula C10H13N5O5; molecular weight 283.24 g/mol.
- Purity 99.5%.
- Available in small milligram pack sizes for research use, e.g., 10 MG.
- For research use only.
Medchemexpress LLC Adenosine, 1-oxide | 146-92-9 | MFCD00037993 | 99.5% | 283.24 g/mol | C10H13N5O5 | 25 MG
Adenosine N1-oxide is a nucleoside derivative used in research as an orally active anti-inflammatory agent. It has been reported to promote osteogenic and adipocyte differentiation and is supplied as a purified research-grade solid with supporting documentation (COA, SDS).
- CAS 146-92-9
- Molecular formula C10H13N5O5
- Molecular weight 283.24 g/mol
- Purity 99.50%
- Available in small vial sizes for research use (e.g., 1-25 mg)
- Documentation: certificate of analysis and safety data sheet available
Medchemexpress LLC Nicotinamide riboside malate | 2415659-01-5 | MFCD34549739 | 99.0% | 388.33 g/mol | C15H20N2O10 | 500MG
Nicotinamide riboside malate is a salt of nicotinamide riboside and malic acid used as an NAD+ precursor and source of vitamin B3. It is employed in biochemical and cellular research to elevate cellular NAD+ levels, probe sirtuin-mediated pathways, and study metabolic and neuroprotective effects in vitro and in vivo models.
- Orally active NAD+ precursor
- Raises cellular NAD+ levels
- Activates sirtuin pathways
- Useful for metabolic and neuroprotection studies
- Stable malate salt suitable for biochemical assays
Medchemexpress LLC L-adenosine | 3080-29-3 | MFCD01075784 | 99.8% | 267.25 g/mol | C10H13N5O4 | 1 ML
L-Adenosine is a metabolically stable enantiomeric analog used as a research probe with weak adenosine deaminase (ADA) inhibitory activity, suitable for studies of adenosine uptake and accumulation.
- 10 mM solution in DMSO, ready for use
- Pack size: 1 mL
- CAS number: 3080-29-3
- Purity: 99.82%
- Molecular weight: 267.25 g/mol
- Store stock solution at -80°C for long-term stability; protect from light
Medchemexpress LLC L-Adenosine | 3080-29-3 | MFCD01075784 | 99.8% | 267.25 | C10H13N5O4 | 10 MG
L-Adenosine is the L-enantiomer of adenosine, a metabolically stable nucleoside analog used as a research probe. It exhibits weak inhibitory activity against adenosine deaminase (ADA) and is used to study adenosine uptake and accumulation.
- CAS number 3080-29-3.
- Molecular formula C10H13N5O4; molecular weight 267.25.
- Purity 99.82% (typical).
- Physical form solid, white to off-white.
- Storage: 4°C, protect from light; in solvent -80°C for 6 months, -20°C for 1 month.
- Reported Ki for ADA: 385 μM.