Chitosan (MW 30000) is a polycationic linear polysaccharide derived from chitin with an average molecular weight of 30000. It is a versatile biomaterial, recognized for its non-toxicity, low allergenicity, biocompatibility, and biodegradability. This compound also demonstrates antitumor, antibacterial, antifungal, and antioxidant activities.
- Reduces growth potential and induces pro-apoptotic effects in certain melanoma cells.
- Low molecular weight forms inhibit bacterial DNA transcription and mRNA synthesis.
- High molecular weight forms alter bacterial cell wall permeability.
- Used in water treatment, wound healing, drug delivery, obesity research, and tissue engineering.
- Reduces aberrant crypt foci formation in colonic precancerous lesions in mice.