Purine nucleosides
Medchemexpress LLC 2'-Deoxyguanosine-13C10,15N5 monohydrate | 2483830-26-6 | 99.8% | 1 MG
2'-Deoxyguanosine-13C10,15N5 (monohydrate) is the 13C and 15N labeled 2'-Deoxyguanosine monohydrate, which is an endogenous metabolite. It is for research use only and not sold to patients.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation during the drug development process.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 2'-deoxyadenosine-13C10 | ≥99.0% | 261.17 | 13C10H13N5O3 | 1 MG
2'-deoxyadenosine-13C10 is a 13C-labeled isotope standard of 2'-deoxyadenosine intended for use as an analytical reference and tracer in biochemical and mass spectrometry assays.
- Isotope-labeled standard for analytical and tracer studies.
- Molecular formula: 13C10H13N5O3.
- Molecular weight: 261.17 g/mol.
- Purity: ≥99.0%.
- Supplied as a 1 mg vial.
- Suitable for use in mass spectrometry and quantitative assays.
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-13C10,15N5 (dilithium) | 1927-31-7 | 99.2% | 517.94 | 1 MG
2'-Deoxyadenosine-5'-triphosphate-13C10,15N5 (dATP-13C10,15N5) dilithium is a 13C and 15N-labeled nucleotide essential for DNA synthesis as a substrate of DNA polymerase. It is valuable in research as:
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 2'-deoxyadenosine | 958-09-8 | MFCD00005754 | 251.24 g/mol | C10H13N5O3 | 500 MG
2'-deoxyadenosine is an adenine nucleoside supplied for research and analytical applications. The compound has been reported to inhibit glucose-stimulated insulin release, activate caspase-3 and promote apoptosis, and inhibit S-adenosyl-L-homocysteine hydrolase (SAHH).
- Adenine nucleoside for research applications.
- Modulates insulin-stimulated cAMP accumulation and insulin release.
- Promotes apoptosis via caspase-3 activation.
- Inhibits S-adenosyl-L-homocysteine hydrolase (SAHH).
- Available from suppliers in small research quantities (supplier pack indicated as 500 MG in provided row data).
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-13C10 dilithium | 1927-31-7 | 95.0% | 512.97 | 1 MG
2'-Deoxyadenosine-5'-triphosphate-13C10 dilithium (dATP-13C10 dilithium) is a 13C-labeled version of 2'-Deoxyadenosine-5'-triphosphate (dATP). dATP is a nucleotide crucial for DNA synthesis or replication in cells, serving as a substrate for DNA polymerase.
- Used as a tracer
- Used as an internal standard for quantitative analysis
- Suitable for analysis by NMR
- Suitable for analysis by GC-MS
- Suitable for analysis by LC-MS
Medchemexpress LLC 2'-deoxyguanosine | 961-07-9 | MFCD00080300 | 99.2% | 267.24 g/mol | C10H13N5O4 | 10 MG
2'-Deoxyguanosine (standard) is the analytical standard of 2'-deoxyguanosine, a purine nucleoside used as an analytical reference and research reagent. Supplied as a high-purity solid, it is intended for analytical assays, method development, and quantitative reference applications.
- Analytical standard suitable for quantitative assays and calibration.
- High purity (99.2%) for reliable analytical results.
- Molecular weight 267.24 g/mol; formula C10H13N5O4 for accurate identification.
- Available in small pack sizes for method development and trace analyses.
- Supplied with certificate of analysis and recommended storage guidance.
Medchemexpress LLC 2'-deoxyguanosine-13C monohydrate | 478511-26-1 | MFCD00080300 | 99.9% | 286.25 g/mol | C9(13)CH15N5O5 | 10 MG
2'-Deoxyguanosine-13C monohydrate is the carbon-13 isotopically labeled form of 2'-deoxyguanosine provided as the monohydrate solid for analytical and research applications, including metabolic flux analysis and isotope-tracing studies. The material is supplied with documentation (COA, SDS) and is intended for research use only.
- 13C labeled 2'-deoxyguanosine.
- Monohydrate solid form.
- Purity: 99.9% (HPLC).
- Molecular weight: 286.25 g/mol.
- Chemical formula: C9(13)CH15N5O5.
- CAS number: 478511-26-1.
- Typical pack size: 10 mg.
- Documentation available: COA and SDS for handling and storage.
- For research use only; not for human use.
Medchemexpress LLC 2′-deoxyguanosine 5′-monophosphate-d12 dilithium | 98.8% | 371.16 g/mol | C10D12Li2N5O7P | 1 MG
2′-Deoxyguanosine 5′-monophosphate-d12 dilithium is a deuterium-labeled deoxyribonucleotide provided as the dilithium salt for research use. It serves as an isotopically labeled standard for spectroscopic analyses and tracing experiments, offering reliable, high-purity material for analytical workflows.
- Deuterium-labeled dGMP (d12) suitable for NMR and mass spectrometry.
- Supplied as the dilithium salt for improved solubility and handling.
- High purity (98.8%) for analytical confidence.
- Molecular formula C10D12Li2N5O7P; molecular weight 371.16 g/mol.
- Available in 1 mg vials; recommended formulation: 100 mM in 26.94 μL Tris HCl/D2O buffer pH 7.5.
- Datasheet, certificate of analysis, and safety data sheet available.
Medchemexpress LLC 2′-deoxyguanosine 5′-monophosphate-13C10,15N5 dilithium | MFCD00080331 | 99.8% | 373.98 g/mol | 13C10H12Li215N5O7P | 5 MG
2′-Deoxyguanosine 5′-monophosphate-13C10,15N5 dilithium is a stable isotope-labeled nucleotide supplied as the dilithium salt for quantitative analytical applications. The 13C and 15N labelling enables accurate tracing and quantitation in mass spectrometry and NMR workflows.
Medchemexpress LLC 2-Deoxyadenosine 5 250mg
2 -Deoxyadenosine 5 -monophosphate disodium a nucleic acid AMP derivative is a deoxyribonucleotide found in DNA 2 -Deoxyadenosine 5 -monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1]
Medchemexpress LLC 2'-Deoxyguanosine monohydrate | 312693-72-4 | 99.7% | 10 G
2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, and it is one of the basic structural units of DNA. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which in turn may affect gene expression or induce cancer.
- Composed of guanine and 2'-deoxyribose.
- Basic structural unit of DNA.
- Oxidation products may participate in DNA damage.
- Can affect gene expression or induce cancer.
- High purity of 99.70%.
- Ships at room temperature.
- Store solid at 4°C, sealed, away from moisture.
- Store in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture.
Medchemexpress LLC 2'-Deoxyguanosine 5'-monophosphate disodium hydrate | 146877-98-7 | 99.0% | C10H14N5O7.H2O.2Na | 100 MG
2'-Deoxyguanosine 5'-monophosphate disodium hydrate (dGMP) is an oxidizable target of the photosensitizer pterin. It can be used to evaluate the photosensitizing properties of biopterins. Pterin causes a photosensitive reaction of dGMP under UV-A radiation, leading to DNA damage. This process involves two main mechanisms in vitro for the photosensitive oxidation of purine nucleotides by pterin.
- A hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism).
- Interaction between dGMP and pterin produces singlet molecular oxygen (1O2) (type II mechanism).