Purine nucleosides
TARGETMOL CHEMICALS INC 6-THIO-2-DEOXYGUANOSINE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 6-Thio-2'-Deoxyguanosine ((beta)-TGdR) is a nucleoside analog and telomerase substrate. purity: 99%
Research Products International Corp 2-Deoxyguanosine mono 1KG
- CAS Number: 961-07-9; 312693-72-4
- Molecular Formula: C10H13N5O4 • H2O
- Molecular Weight: 285.26
Medchemexpress LLC NBI-961 (formerly CMP3a) | 2225902-98-5 | 99.7% | 568.61 g/mol | C28H27F3N6O2S | 10 MG
NBI-961 is a potent NEK2 inhibitor that inhibits proteasomal degradation and induces G2/mitosis arrest and apoptosis in diffuse large B cell lymphoma (DLBCL) cells. It is supplied as a solid, light yellow to yellow research-use-only compound and is available in small amounts for laboratory studies.
- High purity (99.7%).
- Molecular weight 568.61 g/mol.
- Chemical formula C28H27F3N6O2S.
- Soluble in DMSO at 100 mg/mL (requires ultrasonic).
- Powder storage: -20°C for 3 years; 4°C for 2 years.
- Intended for laboratory research use only; not for human or animal use.
Medchemexpress LLC 2'-Deoxyguanosine-13C10,15N5 | 872624-05-0 | 282.13 | 1 MG
2'-Deoxyguanosine-13C10,15N5 is a 13C- and 15N-labeled 2'-Deoxyguanosine for research use only. This compound is used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process, with deuteration showing potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Apexbio Technology LLC 2'-Deoxyguanosine 961-07-9 5g
2 -Deoxyguanosine (CAS 961-07-9) is a purine deoxyribonucleoside comprising guanine coupled to a deoxyribose moiety As an essential constituent of DNA it serves as a substrate in multiple nucleotide metabolism pathways Its interconversion with 2 -deoxyguanosine 5 -monophosphate is mediated by purine 5 -nucleotidase and deoxyguanosine kinase reflecting its role in nucleic acid turnover In biomedical research 2 -deoxyguanosine is utilized to study DNA synthesis repair mechanisms and enzymatic processes involving nucleoside metabolism Altered deoxyguanosine homeostasis has been implicated in purine nucleoside phosphorylase deficiency underscoring its significance in inherited metabolic disorders
Medchemexpress LLC 2'-Deoxyguanosine monohydrate | 312693-72-4 | 99.7% | 5 G
2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, and it is one of the basic structural units of DNA.
- The oxidation products may participate in DNA damage.
- May affect gene expression or induce cancer.
Medchemexpress LLC 2-amino-2'-deoxyadenosine | 4546-70-7 | MFCD00047240 | 99.6% | 266.26 g/mol | C10H14N6O3 | 1 ML
2-Amino-2'-deoxyadenosine is a deoxyribonucleoside analog used as a building block in oligonucleotide synthesis and nucleoside research. It is supplied as a ready-to-use solution in DMSO or as a solid, and is characterized by high purity for laboratory applications.
- Suitable for oligonucleotide synthesis and nucleoside modification studies.
- Available as a 10 mM solution in DMSO and in solid pack sizes for scale-up.
- High purity (99.62%) for research-grade applications.
- Molecular weight 266.26 g/mol; chemical formula C10H14N6O3.
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.89% | 269.26 | 5 G
2'-Deoxyadenosine monohydrate is an adenine nucleoside with multiple biological roles, including inhibiting glucose-stimulated insulin release and islet cyclic AMP (cAMP) accumulation. It activates caspase-3 and promotes apoptosis, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. It has shown an anticancer effect on colon cancer and appears as a white to off-white solid.
- Inhibits glucose-stimulated insulin release
- Inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation
- Activates caspase-3
- Promotes apoptosis
- Inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity
- Demonstrated inhibitory effect on the growth of various cells, including anticancer effect on colon cancer
- Appears as a white to off-white solid
Medchemexpress LLC N6-Isopentenyladenosine | 7724-76-7 | 99.4% | 335.36 | 1 ML
N6-Isopentenyladenosine (Riboprine) is an RNA modification found in cytokinins, which are known to regulate plant growth and differentiation. It is also present in a subset of tRNAs, where it enhances the efficiency and accuracy of translation. This compound is an end product of the mevalonate pathway and functions as an autophagy inhibitor, demonstrating interesting anti-melanoma activity.
- RNA modification found in cytokinins
- Regulates plant growth/differentiation
- Improves efficiency and accuracy of translation in tRNAs
- End product of the mevalonate pathway
- Autophagy inhibitor
- Exhibits anti-melanoma activity
Medchemexpress LLC 2'-Deoxyadenosine 5'-triphosphate disodium | 74299-50-6 | 99.9% | 535.15 | 10 MG
2'-Deoxyadenosine 5'-triphosphate disodium is a nucleotide with important biological activities. It serves as a substrate for a variety of polymerases, including DNA polymerases and reverse transcriptases. This compound plays a key role in DNA synthesis and reverse transcription. It is also widely used in in vitro reactions in molecular biology research.
- Serves as a substrate for a variety of polymerases
- Plays a key role in DNA synthesis
- Plays a key role in reverse transcription
- Widely used in in vitro reactions in molecular biology research
Medchemexpress LLC 7-deaza-2'-deoxyadenosine | 60129-59-1 | >=97.0% | 250.25 g/mol | C11H14N4O3 | 50 MG
7-deaza-2'-deoxyadenosine is a deoxynucleoside analog used in biochemical research and nucleotide chemistry as a building block for oligonucleotide synthesis and related assays. It is typically supplied as a white solid for laboratory research and is intended for research use only.
- deoxynucleoside analog for nucleotide chemistry
- used as a building block in oligonucleotide synthesis
- supplied as a solid in milligram quantities for laboratory research
- intended for research use only, not for human or clinical use
2'-Deoxyadenosine Monohydrate, Thermo Scientific™
CAS: 16373-93-6 Molecular Formula: C10H13N5O3 Molecular Weight (g/mol): 251.25 MDL Number: MFCD00149364 InChI Key: OLXZPDWKRNYJJZ-YUZWJPFSNA-N Synonym: 2'-deoxyadenosine monohydrate,2r,3s,5r-5-6-amino-9h-purin-9-yl-2-hydroxymethyl tetrahydrofuran-3-ol hydrate,adenosine, 2'-deoxy-, monohydrate,2'-deoxyadenosine hydrate,2-deoxyadenosine hydrate,deoxyadenosine hydrate,9-2-deoxy-,a-d-ribofuranosyl adenine,deoxyadenosine monohydrate,2-deoxyadenosine monohydrate,2?-deoxyadenosine monohydrate PubChem CID: 9549172 IUPAC Name: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol SMILES: NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC=N1
MP Biomedicals, Inc 2'-Deoxyguanosine, 99 to 100%, MP Biomedicals™
CAS: 961-07-9 Molecular Formula: C10H13N5O4 Molecular Weight (g/mol): 267.25 MDL Number: MFCD00150760 InChI Key: YKBGVTZYEHREMT-DWFKHXNSNA-N Synonym: 2'-deoxyguanosine,deoxyguanosine,guanine deoxyriboside,2-deoxyguanosine,guanosine, 2'-deoxy,guanine deoxy nucleoside,2'-deoxy-guanosine,2;-deoxyguanosine,unii-g9481n71ro,guanine, 9-2-deoxy-beta-d-erythro-pentofuranosyl PubChem CID: 187790 ChEBI: CHEBI:17172 IUPAC Name: 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one SMILES: NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1
2-Chloro-2'-arabino-fluoro-2'-deoxyadenosine, 99+%, Thermo Scientific Chemicals
CAS: 123318-82-1 Molecular Formula: C10H12ClN5O3 Molecular Weight (g/mol): 285.69 MDL Number: MFCD00871077 InChI Key: ADXUXRNLBYKGOA-GPGUAWMRNA-N Synonym: clofarabine,clolar,evoltra,clofarex,cafda,clofarabina,clofarabinum,clofarabine usan,cl-f-ara-a,c1-f-ara-a PubChem CID: 119182 ChEBI: CHEBI:681569 IUPAC Name: (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol SMILES: NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3Cl)C2=NC=N1
8-Bromo-2'-deoxyguanosine 98.0+%, TCI America™
CAS: 13389-03-2 Molecular Formula: C10H12BrN5O4 Molecular Weight (g/mol): 346.14 MDL Number: MFCD01630971 InChI Key: MKDXZFVCXWXGBQ-QXZWWJJYNA-N PubChem CID: 10947964 ChEBI: CHEBI:61072 IUPAC Name: 2-amino-8-bromo-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one SMILES: NC1=NC2=C(N=C(Br)N2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1