Purine nucleotides
TARGETMOL CHEMICALS INC ADENOSINE AMINE CONGENER 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor. purity: 98%
Medchemexpress LLC Tetrapotassium pyrophosphate | 7320-34-5 | MFCD00011393 | 500g
Potassium diphosphate (tetra-Potassium pyrophosphate) is a kind of biological materials or organic compounds that are widely used in life science research[1]
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5 diphosphate 951G
REAGENT Adenosine 5 diphosphate 951G
Cayman Chemical GunosIn 5-monphosphates 5g
A nucleotide that upon phosphorylation to GTP becomes incorporated into RNA; used to study modulation of glutamatergic neurotransmission
Medchemexpress LLC Sonidegib diphosphate | 1218778-77-8 | 99.97% | 681.49 | 10 MM 1 ML
Sonidegib diphosphate is a potent and selective Smoothened (Smo) antagonist, inhibiting the Hedgehog (Hh) pathway. It has demonstrated antitumor activity in medulloblastoma models and can reduce chronic myeloid leukemia (CML) stem cells.
- Potent and selective Smo antagonist
- Inhibits Hedgehog pathway signaling
- Reduces expression of downstream signaling targets
- Demonstrates dose-related antitumor activity
- Reduces chronic myeloid leukemia stem cells
- Associated with numerous clinical trials
Apexbio Technology LLC Motesanib Diphosphate (AMG-706) 857876-30-3 25mg
Motesanib Diphosphate (AMG-706 CAS 857876-30-3) is an oral small-molecule ATP-competitive inhibitor that targets vascular endothelial growth factor receptors (VEGFR1/2/3) platelet-derived growth factor receptor (PDGFR) c-Kit and Ret with reported IC50 values of 2 84 nM It demonstrates over 1000-fold selectivity for VEGFRs relative to EGFR Src and p38 kinases In vitro Motesanib Diphosphate potently inhibits VEGF-induced proliferation of human endothelial cells (IC50 10 nM) and blocks PDGF- and SCF-induced signaling while showing minimal effects on bFGF-stimulated proliferation In preclinical studies it suppresses angiogenesis and induces regression in tumor xenograft models Motesanib is under investigation in anti-angiogenic cancer research
Medchemexpress LLC Desethyl chloroquine diphosphate | 247912-76-1 | MFCD28138115 | 99.7% | 487.81 | C16H28ClN3O8P2 | 5 MG
Desethyl chloroquine diphosphate is the diphosphate salt of desethyl chloroquine supplied as a research reagent and analytical standard. It is provided as a high-purity solid intended for biochemical, pharmacological, and analytical applications, with documentation including a data sheet and safety data sheet.
- High purity suitable for analytical work (reported 99.7%).
- Diphosphate salt form for improved solubility and stability.
- Molecular weight 487.81 and formula C16H28ClN3O8P2 for accurate calculations.
- Available in small milligram pack sizes for reference and method development.
- Supplied with datasheet and SDS for handling and compliance.
Sigma Aldrich Fine Chemicals Biosciences D Ribulose 15 Diphosphate
Exists as a 557AkDa hexadecamer composed of eight heavy chains each with a molecular weight of approximately 56AkDa and eight light chains of molecular weight 14AkDa. Each molecule contains one magnesium ion. pH optimum ~7.9. KM for CO2 ~0.45 mM. Ribulose diphosphate becomes inhibitory at concentrations exceeding 0.7 mM. Orthophosphate and ammonium sulfate are competitive inhibitors. 3-Phosphoglycerate is a noncompetitive inhibitor.
TARGETMOL CHEMICALS INC ADENOSINE DIALDEHYDE ADO 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Adenosine Dialdehyde (Periodate-oxidized adenosine) is a purine nucleoside analogue. Adenosine Dialdehyde is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo. purity: 95%
Medchemexpress LLC 7-Methylguanosine 5'-diphosphate sodium | 104809-16-7 | 97.1% | C11H16N5NaO11P2 | 1 MG
7-Methylguanosine 5'-diphosphate sodium is a cap analog used in the synthesis of mRNA cap analogues.
- Inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA.
- Is a substrate for T. brucei mRNA decapping enzyme (TbDcp2) which cleaves it from capped RNA to generate pRNA.
Abcam Iodotubercidin, adenosine kinase inhibitor, 1MG
MW 392.15 Da, Purity >95%. Potent, specific adenosine kinase inhibitor (IC₅₀ = 26 nM). Inhibits platelet aggregation and spreading, and interferes with adenosine and adenine nucleotide metabolism. Additionally inhibits other kinases such as ERK2 (Ki = 525 nM).
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Coenzyme A Trilithium Salt | 18439-24-2 | MFCD00075848 | 500mg
Coenzyme A Trilithium Salt | Purity: 93% | Mol Wt: 785.33 | 18439-24-2 | MFCD00075848 | 500mg
Medchemexpress LLC Adenosine 5'-monophosphate (monohydrate) | 18422-05-4 | 98.9% | C10H16N5O8P | 100 MG
Adenosine 5'-monophosphate monohydrate is an analytical standard intended for research and analytical applications. It is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Used as an analytical standard
- Reference standard supplied assay
- Commonly used in qualitative research experiments
- Commonly used in quantitative research experiments
- Commonly used in methodological research experiments
- Suitable for HPLC, GC, and MS applications
- For research use only
Medchemexpress LLC Guanosine, 6-O-methyl- | 7803-88-5 | 99.7% | 297.27 | 100 MG
6-O-Methyl Guanosine is a modified nucleoside that inhibits colony-forming ability in a malignant xeroderma pigmentosum cell line.
- Modified nucleoside
- Inhibits colony-forming ability in a malignant xeroderma pigmentosum cell line
- For research use only