Drug Standards
Medchemexpress LLC Fexofenadine | 83799-24-0 | 99.8% | 1 ML
Fexofenadine is an orally active and nonsedative H1 receptor antagonist, suitable for research into allergic rhinitis and chronic idiopathic urticarial. It is provided as a 10 mM solution in DMSO.
- Active and nonsedative H1 receptor antagonist
- Can be used in allergic rhinitis research
- Can be used in chronic idiopathic urticarial research
- Purity of 99.8%
Medchemexpress LLC Loxapine (succinate) | 27833-64-3 | 98.8% | 445.90 | 10 MM 1 ML
Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist, and a dibenzoxazepine anti-psychotic agent. It can also suppress bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant *Salmonella enterica* serovar Typhimurium in macrophages.
- Orally active dopamine inhibitor
- 5-HT receptor antagonist
- Dibenzoxazepine anti-psychotic agent
- Suppresses bacterial efflux pump activity
- Inhibits intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages
Medchemexpress LLC (R)-Donepezil ((R)-E2020 free base) | 142698-19-9 | 99.91% ee.: 100.00% | 379.49 | 100 MG
(R)-Donepezil is an R-enantiomer of Donepezil, a specific and potent Acetylcholinesterase (AChE) inhibitor. It is provided as a solid, white to off-white in appearance.
- Specific and potent AChE inhibitor
- R-enantiomer of Donepezil
- Molecular weight: 379.49
- Purity: 99.91%
Medchemexpress LLC Latanoprost lactone diol | 145667-75-0 | MFCD05865275 | 99.9% | 304.38 g/mol | C18H24O4 | 10MM 1ML
Latanoprost lactone diol is a synthetic intermediate used in the preparation of latanoprost, a prostaglandin F2α analogue and FP receptor agonist that lowers intraocular pressure. The compound is provided for research purposes in ready-to-use solution or solid form and is characterized for purity and molecular identity.
- Intermediate in prostaglandin synthesis
- Supplied as a 10 mM solution in DMSO, 1 mL
- Also available as a solid with solvent for reconstitution
- High purity (99.86% reported)
- Molecular weight 304.38 g/mol
- Intended for research use
Medchemexpress LLC Plerixafor octahydrochloride | 155148-31-5 | MFCD04974488 | 99.1% | 794.47 g/mol | C28H62Cl8N8 | 10 MG
Plerixafor octahydrochloride is a small-molecule selective antagonist of the CXCR4 chemokine receptor provided for laboratory research use. It exhibits reported CXCR4 inhibitory activity and is used in studies of stem cell mobilization, HIV, cancer, and immunology.
- Selective CXCR4 antagonist with IC50 44 nM.
- Chemical formula C28H62Cl8N8 and molecular weight 794.47 g/mol.
- High purity (≈99.1%) suitable for analytical and research applications.
- CAS number 155148-31-5 for unambiguous substance identification.
- Supplied in milligram-scale packages for laboratory research.
Medchemexpress LLC Butylparaben (standard) | 94-26-8 | 98.9% | 100 MG
Butylparaben (Standard) is the analytical standard of Butylparaben. It is an organic compound used as an antimicrobial preservative in cosmetics, in active molecule suspensions, and as a food flavoring additive. This product is intended for research and analytical applications, particularly as a reference standard in qualitative, quantitative, and methodological research experiments using techniques like HPLC, GC, and MS.
- Analytical standard
- Used as an antimicrobial preservative in cosmetics
- Found in active molecule suspensions
- Used as a food flavoring additive
- Intended for research and analytical applications
- Reference standard for qualitative, quantitative, and methodological research
- Suitable for techniques such as HPLC, GC, and MS
Medchemexpress LLC Tenofovir Disoproxil fumarate | 202138-50-9 | 99.7% | 635.51 | 1 ML
Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. It is used to treat HIV and chronic Hepatitis B.
- Used to treat HIV and chronic hepatitis B
- Shows cytotoxic effects on HK-2 cells
- Diminishes ATP levels in HK-2 cells
- Increases oxidative stress in HK-2 cells
- Induces apoptosis via mitochondrial damage in HK-2 cells
- Inhibits HIV replication in activated PBMCs
- Exhibits synergistic antiretroviral activity with M48U1 formulation
- Demonstrates dose-dependent activity during vaginal HIV challenge in BLT mice
- Reduces HIV transmission in BLT mice
- Induces dose-dependent decline in serum viremia in woodchucks
Medchemexpress LLC Ranitidine | 66357-35-5 | 99.9% | 250 MG
Ranitidine is a potent, selective, and orally active histamine H2-receptor antagonist that inhibits gastric secretion. It antagonizes histamine-induced increases in guinea-pig isolated rat atrium and histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. It also inhibits breast tumor development and spread in mice.
- Inhibits gastric secretion
- Antagonizes histamine-induced increases in guinea-pig isolated rat atrium
- Antagonizes histamine-induced relaxations of the rat isolated uterine horn
- Inhibits breast tumor development and spread in mice
- Reduces CD11b+Ly6Chi cells in spleen and bone marrow
- Inhibits lung metastasis
- Inhibits primary tumor growth
- Increases the latency of breast tumorigenesis and reduces tumor count
Apexbio Technology LLC Folic acid 59-30-3 5g
Folic acid (CAS 59-30-3) is a water-soluble B9 vitamin structurally derived from Spinacia oleracea It functions as a cofactor in one-carbon transfer reactions facilitating nucleotide synthesis and methylation processes essential for DNA replication and cellular division Due to its involvement in folate metabolism folic acid is frequently utilized in studies of cell proliferation gene expression regulation and metabolic disorders For optimal stability folic acid should be stored in a sealed container under cool dry conditions
Medchemexpress LLC Fostamatinib disodium hexahydrate | 914295-16-2 | 99.5% | 50 MG
Fostamatinib disodium hexahydrate is an oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor, also inhibiting Lyn and Lck. This product is for research use only.
- Oral proagent of R406
- Orally available
- Competitive Syk/FLT3 inhibitor
- Inhibits Lyn and Lck
- For research use only
Selleck Chemical LLC Onalespib (AT13387) S1163-5mg
Onalespib (AT13387) is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells displays a long duration of anti-tumor activity Phase 2
Apexbio Technology LLC Elacridar(Synonyms: GF120918, GG918, GW0918, GF-120918, GG-918, GW-0918), 100mg, CAS: 143664-11-3.
Elacridar (CAS 143664-11-3) is a potent inhibitor of P-glycoprotein (P-gp) a transmembrane efflux transporter belonging to the MDR/TAP subfamily P-gp actively exports diverse xenobiotics and drugs from cells significantly influencing drug bioavailability and distribution Elacridar inhibits P-gp with an IC50 of approximately 193 nM and markedly reduces transporter activity in P-gp-overexpressing MDCKII cell models at concentrations as low as 1 M In mice elacridar administration (10 mg/kg) enhances brain penetration of P-gp substrates such as sunitinib Thus elacridar is extensively used in biomedical research to study drug transport mechanisms and multidrug resistance
Medchemexpress LLC Bromfenac (sodium) | 91714-93-1 | 99.9% | 5MG
Bromfenac (sodium) | 91714-93-1 | 99.9% | 5MG
Medchemexpress LLC (±)-Naproxen | 23981-80-8 | MFCD00439456 | C14H14O3 | 10 G
(±)-Naproxen, also known as (Rac)-Naproxen, is a racemate of Naproxen. It functions as an inhibitor for both COX-1 and COX-2 with IC50s of 8.72 μM and 5.15 μM respectively. This compound has a molecular formula of C14H14O3 and a molecular weight of 230.26, presenting as a white to light yellow solid. It is intended for research use only.
- Inhibits COX-1 and COX-2
- Molecular weight 230.26
- White to light yellow solid
- Store powder at -20°C for 3 years, 4°C for 2 years
- Store in solvent at -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at 100 mg/mL