Drug Standards
Medchemexpress LLC 4-bromo-1-chloro-2-(2-ethoxybenzyl)benzene | 1830346-16-1 | MFCD22683795 | 50mg
Dapagliflozin impurity 2 is an impurity of Dapagliflozin (HY-10450)
Medchemexpress LLC (S)-crizotinib | 1374356-45-2 | MFCD22126092 | 99.8% | 450.34 | C21H22Cl2FN5O | 1 ML
(S)-Crizotinib is the S-enantiomer of crizotinib supplied for research use as a stereochemically defined small molecule active against MTH1 and used in studies of DNA/RNA synthesis and apoptosis. It is provided as a ready-to-use solution in DMSO or as solid material for biochemical and cellular assays.
- Stereochemically pure S-enantiomer suitable for enantiomer-specific studies.
- Selective MTH1 inhibitor for biochemical and cellular assays.
- High purity, 99.8% (HPLC), suitable for research applications.
- Available as a 10 mM solution in DMSO (1 ML) and in multiple solid sizes.
- Molecular weight 450.34 and formula C21H22Cl2FN5O for reference.
Medchemexpress LLC Econazole ((±)-Econazol) | 27220-47-9 | MFCD00800993 | 99.93% | 1 ML
Econazole is an orally active imidazole antifungal agent. It also acts as a cytochrome P-450 inhibitor and blocks calcium and manganese ion uptake. It demonstrates activity against various fungi and certain Gram-positive bacteria, though it is not significantly active against Gram-negative bacteria. Furthermore, Econazole can suppress prostaglandin synthesis and may induce liver damage.
- Orally active imidazole antifungal agent
- Inhibitor of cytochrome P-450
- Blocks calcium and manganese ion uptake
- Active against a variety of fungi
- Active against some Gram-positive bacteria
- Can inhibit the synthesis of prostaglandins
Medchemexpress LLC Benzethonium chloride | 121-54-0 | 98.47% | 1 ML
Benzethonium chloride is a chemical compound known for its microbiocidal properties. It inhibits nicotinic acetylcholine receptors in human recombinant α7 and α4β2 neurons in Xenopus laevis oocytes. This compound exhibits antibacterial, anticancer, antisepsis, and disinfection activities, making it suitable for various research applications.
- Induces apoptosis and activates caspases in cancer cell lines
- Ablates the tumor-forming ability of FaDu cells
- Delays the growth of xenograft tumors in vivo
- Effective against human A549, CCRF-CEM, HUVEC, HeLa, MCF7, and MDA-MB-231 cells
- Shows acute toxicity in C. elegans and affects hatching and mortality in zebrafish embryos
Selleck Chemical LLC Donepezil HCl S2462-1g
Donepezil HCl is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8 12 nM and 11 6 nM respectively This product is not soluble in PBS solution Please do not dissolve it in PBS for administration
Medchemexpress LLC Berberine sulfate | 633-66-9 | 433.43 | 5 G
Berberine sulfate, an alkaloid isolated from the Chinese herbal medicine Huanglian, functions as an antibiotic and exhibits antineoplastic properties. It induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. The sulfate form is recognized for its improved bioavailability.
- Isolated from Coptis chinensis Franch.
- Acts as an antibiotic
- Induces reactive oxygen species (ROS) generation
- Inhibits DNA topoisomerase activity
- Possesses antineoplastic properties
- Improved bioavailability due to sulfate form
- Purity of 99.23%
- Inhibits proliferation of various colorectal carcinoma cell lines
- Suppresses expression of key cell cycle proteins
- Inhibits growth of human colorectal adenocarcinoma xenografts
Selleck Chemical LLC GSK J4 HCl (GSKJ4 HCl) 10mM/1mL 1797983-09-5
GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM in a cell-free assay and inactive against a panel of demethylases of the JMJ family. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Iohexol | 66108-95-0 | 99.5% | 1 ML
Iohexol is a non-ionic, water-soluble contrast agent that serves as a reference marker for determining glomerular filtration rate (GFR) at the level of renal function.
- Can be used for contrast in myelography.
- Suitable for computerized tomography (cisternography, ventriculography).
- Applicable for MicroCT imaging.
Cayman Chemical AmInopterIn 50mg
A synthetic folic acid derivative with anticancer and immunosuppressive properties; used in HAT media for selection in mammalian cell culture
Medchemexpress LLC Betamethasone | 378-44-9 | MFCD00062969 | >=98.0% | C22H29FO5 | 10MG
Betamethasone is a synthetic glucocorticoid corticosteroid with potent anti-inflammatory and immunosuppressive activity. Supplied as a high-purity analytical standard, it is intended for research and laboratory use including assay development, method validation, and as a reference material in chromatographic and spectrometric analyses.
- High purity suitable for analytical use.
- Verified identity and assay for reliable standardization.
- Solid form for accurate weighing and easy dissolution.
- Compatible with LC, GC, and MS analytical methods.
- Applicable to assay development, method validation, and calibration.
Sigma Aldrich Fine Chemicals Biosciences Kaempferol Pharmaceutical30mg
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Medchemexpress LLC Escitalopram (oxalate) (Standard) | 219861-08-2 | 99.7% | C22H23FN2O5 | 1 ML
Escitalopram ((S)-Citalopram) oxalate is the S-enantiomer of racemic Citalopram, functioning as a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. It exhibits significantly higher binding affinity compared to its R(-)-enantiomer and demonstrates selectivity over both dopamine and norepinephrine transporters. This antidepressant is utilized in research for major depression.
- Selective serotonin reuptake inhibitor (SSRI)
- Ki of 0.89 nM (serotonin transporter)
- Approximately 30-fold higher binding affinity than its R(-)-enantiomer
- Selective over dopamine transporter (DAT) and norepinephrine transporter (NET)
- Used for major depression research
Medchemexpress LLC Escitalopram (oxalate) | 219861-08-2 | 99.9% | C22H23FN2O5 | 100 MG
Escitalopram oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM for the serotonin transporter. It exhibits approximately 30-fold higher binding affinity than its R(-)-enantiomer and selectivity over dopamine and norepinephrine transporters. This compound is primarily utilized as an antidepressant in the research of major depression and for various neurological disease studies. This product is intended for research and analytical applications only.
- High purity for reliable research applications
- Selective serotonin reuptake inhibitor
- Suitable for neurological disease research
- Used in studies of major depression
- For research use only
Cayman Chemical RacecadotrIl 250mg
A prodrug form of thiorphan; reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats at 80 or 100 mg/kg, respectively; decreases duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea