Drug Standards
Apexbio Technology LLC Tofacitinib (CP-690550,Tasocitinib) 477600-75-2 10mM (in 1mL DMSO)
Tofacitinib (CP-690550 Tasocitinib CAS 477600-75-2) is an orally bioavailable Janus kinase (JAK) inhibitor employed as a targeted immunomodulator The compound preferentially inhibits signaling mediated by JAK1 and JAK3 heterodimers displaying functional selectivity and less pronounced effects on JAK2 pathways Such inhibition disrupts downstream cytokine signaling notably IL-2 IL-4 IL-7 IL-9 IL-15 and IL-21 cytokines implicated in lymphocyte activation proliferation and differentiation Recent studies also indicate suppression of STAT signaling and potential modulation of additional kinase targets Tofacitinib is broadly studied in autoimmune research especially in rheumatoid arthritis and ulcerative colitis models
Medchemexpress LLC ARQ 621 | 1095253-39-6 | MFCD25976786 | 99.0% | 552.43 g/mol | C28H24Cl2FN5O2 | 10 MG
ARQ 621 is a small-molecule, allosteric inhibitor of the mitotic motor protein Eg5 (kinesin spindle protein), used in biochemical and cell-based research to evaluate antiproliferative and mitotic-disruption effects.
- Potent and selective Eg5 inhibitor with antitumor activity.
- Purity ≥99.0%.
- Molecular weight 552.43 g/mol.
- Chemical formula C28H24Cl2FN5O2.
- Solid, white to off-white powder; soluble in DMSO (110 mg/mL).
- Store protected from light at -20°C; in solution, store at -80°C for up to 6 months.
U.S. Pharmacopeia Lorazepam Related Compound B, 2958-36-3, MFCD00007840, 25 mg
Linear Formula: H2NC6H3(Cl)COC6H4Cl, Molecular Weight: 266.12, mp: 87-89 °C, Synonym: 2-Amino-2′,5-dichlorobenzophenone.
Sigma Aldrich Fine Chemicals Biosciences Famotidine Related Compound F United States Pharmacopeia (USP) Reference Standard | 107880-74-0 | 25MG
Famotidine Related Compound F United States Pharmacopeia (USP) Reference Standard | Mol Wt: 260.34 | 107880-74-0 | 25MG
Sigma Aldrich Fine Chemicals Biosciences Daunorubicinone United States Pharmacopeia (USP) Reference Standard | 21794-55-8 | 25MG
Daunorubicinone United States Pharmacopeia (USP) Reference Standard | Mol Wt: 398.36 | 21794-55-8 | 25MG
Medchemexpress LLC Naphazoline | 835-31-4 | 99.7% | 210.27 | 50 MG
Naphazoline is a potent α-adrenergic receptor agonist that reduces vascular hyperpermeability and promotes vasoconstriction. It also reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. It can be used for non-bacterial conjunctivitis research.
- Reduces vascular hyperpermeability.
- Promotes vasoconstriction.
- Reduces inflammatory factors.
- Reduces cytokines.
- Reduces IgE, GMCSF, and NGF.
- Suitable for non-bacterial conjunctivitis research.
Medchemexpress LLC Talazoparib tosylate | 1373431-65-2 | 507274 | 99.9% | 552.55 | 50 MG
Talazoparib tosylate (BMN 673ts) is a novel, potent, and orally available PARP1/2 inhibitor with an IC50 of 0.57 nM for PARP1. It is for research use only and has not been fully validated for medical applications.
- Potent PARP1/2 inhibitor
- Orally available
- Suitable for research applications
TARGETMOL CHEMICALS INC DINOPROST TROMETHAMINE S 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dinoprost tromethamine salt (PGF2(alpha) THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. purity: 99%
Medchemexpress LLC Naphazoline | 835-31-4 | 99.7% | 210.27 | 100 MG
Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist that reduces vascular hyperpermeability and promotes vasoconstriction. It can also reduce levels of inflammatory factors, cytokines, IgE, GMCSF, and NGF, making it suitable for non-bacterial conjunctivitis research.
- Reduces vascular hyperpermeability
- Promotes vasoconstriction
- Reduces levels of inflammatory factors (TNF-α, IL-1β and IL-6)
- Reduces levels of cytokines (IFN-γ and IL-4)
- Reduces levels of IgE, GMCSF, and NGF
- Can be used for non-bacterial conjunctivitis research
Medchemexpress LLC Folic acid | 59-30-3 | 99.0% | 441.40 | 1 ML
Folic acid is an orally active essential nutrient from the B complex group of vitamins. It has shown antidepressant-like effects and can reduce the risk of neonatal neural tube defects. It can also be used in research for megaloblastic and macrocytic anemias due to its deficiency.
- An orally active essential nutrient from the B complex group of vitamins.
- Shows antidepressant-like effects.
- Reduces the risk of neonatal neural tube defects.
- Can be used to research megaloblastic and macrocytic anemias due to its deficiency.
Medchemexpress LLC Itacitinib adipate | 1334302-63-4 | 99.2% | 699.66 | 5 MG
Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor that has been tested for efficacy and safety in a phase II trial in myelofibrosis. It is suitable for research use only.
- Orally bioavailable
- Selective JAK1 inhibitor
- Tested in phase II trial for myelofibrosis
- Suitable for research use
Medchemexpress LLC Ranitidine | 66357-35-5 | MFCD00081180 | 99.9% | 25 MG
Ranitidine is a potent, selective, and orally active histamine H2-receptor antagonist that inhibits gastric secretion. It has been shown to inhibit breast tumor development and spread in mice, and also antagonizes histamine-induced effects in isolated rat tissues.
- Potent, selective, and orally active H2-receptor antagonist
- Inhibits gastric acid secretion
- Antagonizes histamine-induced effects in isolated rat atrium and uterine horn
- Inhibits breast tumor development and spread
- Reduces specific myeloid cell populations in mice
- Increases latency of breast tumorigenesis
Medchemexpress LLC Ketorolac (tromethamine salt) | 74103-07-4 | MFCD00887595 | 99.5% | 1 G
Ketorolac tromethamine salt is a non-steroidal anti-inflammatory agent that acts as a nonselective COX inhibitor. With IC50s of 20 nM for COX-1 and 120 nM for COX-2, this compound is intended for laboratory chemical use and substance manufacturing, and is for research use only.
- Non-steroidal anti-inflammatory agent
- Nonselective COX inhibitor
- Solid appearance
- Purity of 99.5%
- IC50 of 20 nM for COX-1
- IC50 of 120 nM for COX-2
Medchemexpress LLC Nitisinone | 104206-65-7 | 99.93% | 5 MG
Nitisinone is an orally active, competitive, and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor. It promotes tyrosine accumulation in a dose-dependent manner and is utilized in studies of hereditary tyrosinemia type 1 (HT-1) and albinism.
- Orally active 4-HPPD inhibitor
- Promotes tyrosine accumulation
- Used in studies of hereditary tyrosinemia type 1 (HT-1)
- Applicable in albinism research
- Purity of 99.93%
Medchemexpress LLC Nitisinone | 104206-65-7 | 100 MG
Nitisinone is an orally active, competitive, and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. It promotes tyrosine accumulation in a dose-dependent manner and can be used in studies of hereditary tyrosinemia type 1 (HT-1) and albinism.
- Orally active and competitive 4-HPPD inhibitor
- Promotes tyrosine accumulation
- Useful in studies of hereditary tyrosinemia type 1 (HT-1)
- Applicable in studies of albinism