Drug Standards
TARGETMOL CHEMICALS INC OPROZOMIB 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Oprozomib (PR-047) (ONX 0912) an inhibitor for CT-L activity of 20S proteasome (beta)5(IC50=36 nM)/LMP7(IC50=82 nM) is orally bioavailable. Oprozomib also has potential antineoplastic activity. purity: 99%
Medchemexpress LLC Colchicine | 64-86-8 | 99.93% | 399.44 | 25 MG
Colchicine (Standard) is the analytical standard for Colchicine, an orally active alkaloid. It acts as a potent tubulin inhibitor and a microtubule disrupting agent, inhibiting microtubule polymerization with an IC50 of 3 nM. It also functions as a competitive antagonist of α3 glycine receptors (GlyRs) and can prevent NSAID-induced small intestinal injury. Colchicine demonstrates extensive anti-inflammatory, immunosuppressive, and anti-fibrosis effects, suggesting its potential for gouty arthritis research.
- Analytical standard for research and analytical applications.
- Potent tubulin inhibitor and microtubule disrupting agent.
- Inhibits microtubule polymerization with an IC50 of 3 nM.
- Competitive antagonist of the α3 glycine receptors (GlyRs).
- Prevents NSAID-induced small intestinal injury.
- Extensive anti-inflammatory, immunosuppressive, and anti-fibrosis effects.
- Potential for gouty arthritis research.
![Medchemexpress LLC (2-chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone | 915095-87-3 | MFCD22665921 | 100mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000270120.png-250.jpg)
Medchemexpress LLC (2-chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone | 915095-87-3 | MFCD22665921 | 100mg
Empagliflozin impurity 108 is an impurity of Empagliflozin (HY-15409)
Medchemexpress LLC Cefaclor | 53994-73-3 | 98.5% | 1 ML
Cefaclor is a well-absorbed orally active cephalosporin antibiotic that specifically binds to penicillin-binding protein 3 (PBP3). It is used in research for various bacterial infections, including respiratory tract infections, bacterial bronchitis, pharyngitis, and skin infections, and also for depression studies.
- Specifically binds to penicillin-binding protein 3 (PBP3)
- Used for research on depression
- Active against various bacterial infections, such as respiratory tract infections, bacterial bronchitis, pharyngitis, and skin infections
- Well-absorbed orally active cephalosporin antibiotic
Medchemexpress LLC Fluticasone | 90566-53-3 | 98.7% | 5 MG
Fluticasone is an inhaled corticosteroid used for respiratory research. It functions as a Smo agonist with an IC50 value of 99 nM, and also activates Hedgehog signaling. It stimulates the proliferation of primary neuronal stem or precursor cells. This product is for research use only and not intended for patient use.
- Acts as a Smo agonist with an IC50 value of 99 nM.
- Activates Hedgehog signaling.
- Stimulates proliferation of primary neuronal stem or precursor cells.
- Inhibits U2OS cell growth.
- Reduces HRV-induced mucin production.
- Suppresses rhinovirus-induced airway inflammation.
Medchemexpress LLC Econazole | 27220-47-9 | 99.9% | 100 MG
Econazole is an orally active imidazole antifungal agent that also functions as a cytochrome P-450 inhibitor and blocks calcium and manganese ion uptake. It demonstrates effectiveness against various fungi and certain Gram-positive bacteria, though it is not significantly active against Gram-negative bacteria. Econazole can inhibit prostaglandin synthesis and may induce liver damage.
- Orally active imidazole antifungal agent
- Functions as a cytochrome P-450 inhibitor
- Blocks calcium and manganese ion uptake
- Effective against various fungi
- Effective against some Gram-positive bacteria
- Can inhibit prostaglandin synthesis
Medchemexpress LLC Bisoctrizole | 103597-45-1 | 98.0% | 5 G
Bisoctrizole is a broad-spectrum UVA/UVB absorber from the benzotriazole class. It works by absorbing UV light through its hydroxyphenyl groups, converting light energy into heat to prevent UV-induced damage to materials or skin. It is effective in absorbing UVA (320-400 nm) and some UVB (280-320 nm) radiation.
- Delays photodegradation of materials like silicones
- Improves UV aging resistance
- Enhances the photoprotective capabilities of sunscreen products
- Intended for research use only
Medchemexpress LLC Econazole ((±)-Econazol) | 27220-47-9 | 99.9% | 1 G
Econazole is an orally active imidazole antifungal agent, a cytochrome P-450 inhibitor, and a blocker of calcium and manganese ion uptake. It is active against various fungi and some Gram-positive bacteria, but not against Gram-negative bacteria. Econazole can inhibit prostaglandin synthesis and can also induce liver damage.
- Imidazole antifungal agent.
- Cytochrome P-450 inhibitor.
- Blocks calcium and manganese ion uptake.
- Effective against various fungi and some Gram-positive bacteria.
- Inhibits prostaglandin synthesis.
- Solid appearance.
- White to off-white color.
Medchemexpress LLC Ketorolac | 74103-06-3 | 99.9% | 100 MG
Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that functions as a nonselective COX inhibitor. It is utilized in ophthalmic solutions for various conditions and also serves as a DDX3 inhibitor for cancer research. This product is stable under recommended storage conditions and is intended for laboratory use only.
- Non-steroidal anti-inflammatory drug (NSAID)
- Nonselective COX inhibitor
- Used in ophthalmic solutions
- DDX3 inhibitor for cancer research
- Stable under recommended storage conditions
- For research use only
n1cc(cn1)-c1ncnc2[nH]ccc12 | 5mg | 335407467](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697931.jpg-250.jpg)
eMolecules 941678-49-5 | Ruxolitinib | Target Molecule | MFCD12031592 | 306.373 | C17H18N6 | 0.000 | N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12 | 5mg | 335407467
Ruxolitinib | Target Molecule | 941678-49-5 | MFCD12031592 | 306.373 | C17H18N6 | 0.000 | N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12 | 5mg | 335407467
Apexbio Technology LLC Spironolactone 52-01-7 1g
Spironolactone (52-01-7) is a small-molecule antagonist targeting mineralocorticoid (aldosterone) and androgen receptors It is designed to block receptor-mediated signaling thereby affecting sodium and potassium balance and pathways related to androgen signaling Spironolactone exerts its biological activity primarily through competitive inhibition of mineralocorticoid and androgen receptors In in vitro studies spironolactone demonstrates antagonistic activity with an IC50 value of 24 nM for mineralocorticoid receptors and 77 nM for androgen receptors Based on these pharmacological properties spironolactone holds research potential in studies of hormone signaling sodium homeostasis and androgen receptor-mediated gene expression in endocrine or cancer research
Medchemexpress LLC Ethacrynic acid | 58-54-8 | 99.98% | 100 MG
Ethacrynic acid is an orally active diuretic with anti-inflammatory and anticancer activity. It is an inhibitor of glutathione S-transferase (GSTs) and Wnt signaling pathways, and also functions as a radiosensitizer. Ethacrynic acid can inhibit airway smooth muscle (ASM) contraction in mice and can increase the outflow of aqueous humor from the eye for the study of glaucoma.
- Anti-inflammatory activity
- Anticancer activity
- Orally active diuretic
- Inhibitor of glutathione S-transferase (GSTs) and Wnt signaling pathways
- Radiosensitizer
- Can inhibit airway smooth muscle (ASM) contraction in mice
- Can increase the outflow of aqueous humor from the eye for the study of glaucoma
Medchemexpress LLC Cinacase impurity 12 | 1229224-93-4 | 98.5% | 361.44 | C22H26F3N | 10 MG
Cinacase impurity 12 is an identified impurity of cinacase provided for laboratory research and analytical use. It is supplied as a high-purity liquid suitable as an analytical reference and for stability testing.
- Purity 98.48%
- CAS number 1229224-93-4
- Molecular weight 361.44
- Chemical formula C22H26F3N
- Appearance liquid
- Storage: pure form -20°C (3 years) or 4°C (2 years)
- In solvent: -80°C (6 months) or -20°C (1 month)
- Available sizes include 5 mg, 10 mg, 25 mg, 50 mg, 100 mg
Medchemexpress LLC Mogroside IV | 89590-95-4 | 98.6% | 1125.29 | 5 MG
Mogroside IV is a triterpenoid glycoside isolated from Luo Han Guo extracts. It serves as a nonsugar sweetener, known to be sweeter than sucrose, and is derived from the plant Siraitia grosvenorii. This compound, along with other mogrosides, demonstrates various biological activities including antioxidant, antidiabetic, and anticancer properties.
- Triterpenoid glycoside structure
- Derived from Siraitia grosvenorii (Luo Han Guo)
- Functions as a nonsugar sweetener
- Sweeter than sucrose
- Exhibits antioxidant properties
- Demonstrates antidiabetic effects
- Possesses anticancer activities
- Appears as a white to off-white solid
Echelon Biosciences Research Labs Ins(1,3,4)P3 100 ug
Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1,3,4-trisphosphate (Ins(1,3,4)P3) is an intermediate in the inositol phosphate pathway. Ins(1,3,4)P3 inhibits Ins(3,4,5,6)P4 1-kinase which regulates Ins(3,4,5,6)P4 levels. Ins(3,4,5,6)P4 in turn is responsible for inhibiting calcium-activated chloride channels. Ins(1,3,4)P3 is produced by dephosphorylation of Ins(1,3,4,5)P4 by a 5-phosphatase. Ins(1,3,4)P3 is a substrate for phosphatases yielding Ins(1,3)P2 and Ins(3,4)P2. This item is non returnable
