Hydrochlorides
Medchemexpress LLC Kari 201 hydrochloride | 2376132-24-8 | 320.86 | 5 MG
KARI 201 hydrochloride is a selective, brain penetrant pan-competitive acid sphingomyelinase (ASM) inhibitor with an IC50 of 338.3 nM. It also acts as a ghrelin receptor agonist.
- Selective, brain penetrant pan-competitive acid sphingomyelinase (ASM) inhibitor
- Ghrelin receptor agonist
- Improves neuropathological features of Alzheimer's disease
Medchemexpress LLC Azd-7762 hydrochloride | 1246094-78-9 | 99.58% | 398.88 | 50 MG
Azd-7762 hydrochloride | 1246094-78-9 | 99.58% | 398.88 | 50 MG
Apexbio Technology LLC Dapoxetine HCl 129938-20-1 50mg
Dapoxetine hydrochloride (CAS 129938-20-1) is a short-acting selective serotonin reuptake inhibitor (SSRI) It exerts its pharmacological effect by inhibiting the reuptake of serotonin (5-HT) at the presynaptic membrane thereby increasing serotonin activity in the synaptic cleft This modulation of serotonergic neurotransmission has been shown to delay ejaculation latency making dapoxetine hydrochloride an established model compound for investigating serotonergic regulation of ejaculatory control It is widely used in research on the neurobiology and therapeutic approaches to premature ejaculation and related disorders
Medchemexpress LLC Mln120b dihydrochloride | 1782573-78-7 | C19H17Cl3N4O2 | 50 MG
MLN120B dihydrochloride is a potent, orally active IKKβ inhibitor (IC50 60 nM) that inhibits multiple myeloma cell growth in vitro and in vivo. It is also used for rheumatoid arthritis research. In vitro, it blocks IκB phosphorylation/degradation and TNF-a-induced p65 NF-κB phosphorylation, reducing proliferation in various multiple myeloma cell lines. In vivo, oral administration reduces tumor growth markers and protects against bone and cartilage destruction in rheumatoid arthritis models.
- Potent, ATP competitive, orally active IKKβ inhibitor.
- Inhibits IκB phosphorylation and degradation.
- Blocks TNF-a-induced p65 NF-κB phosphorylation.
- Reduces proliferation of multiple myeloma cells.
- Inhibits IL-6 secretion from BMSCs.
- Protects against bone and cartilage destruction in rheumatoid arthritis models.
- Prolongs survival in treated animals.
Medchemexpress LLC MRT68921 dihydrochloride | 2080306-21-2 | 99.7% | 507.50 g·mol^-1 | C25H36Cl2N6O | 1 MG
MRT68921 dihydrochloride is a potent dual NUAK1/ULK1 kinase inhibitor used in cancer and autophagy research. It inhibits ULK1 and ULK2 at low nanomolar concentrations, disrupts autophagy, and promotes apoptosis; the compound is supplied as a solid with documented solubility and storage recommendations for research use.
- Inhibits ULK1 and ULK2 at low nanomolar potency.
- Blocks cellular autophagy and promotes apoptosis.
- High reported purity suitable for biochemical assays.
- Soluble in water and DMSO with specified preparation conditions.
- Stable when stored sealed at recommended temperatures.
- Supplied in small solid package sizes for research use.
Medchemexpress LLC 2-iminothiolane hydrochloride | 4781-83-3 | MFCD00039013 | 99.9% | 137.63 | C4H8ClNS | 1 G
2-Iminothiolane hydrochloride is a thiolating reagent used to introduce sulfhydryl (-SH) groups onto primary amines of proteins, peptides, and oligosaccharides, facilitating labeling, conjugation, and modification workflows.
- Converts primary amines to free sulfhydryl groups for downstream conjugation.
- Reacts efficiently at pH 7-10 to form amidine linkages while introducing thiol functionality.
- High purity minimizes side reactions and contaminants.
- Solid powder; store sealed at 4°C; in solution store -80°C (6 months) or -20°C (1 month).
- Available in lab-scale sizes suitable for research, including 1 g.
Medchemexpress LLC Prodipine hydrochloride | 31314-39-3 | 99.8% | 315.9 g/mol | C20H26ClN | 10 MG
Prodipine hydrochloride is a diphenyl-phosphonate derivative used as a research DPP-IV inhibitor. It has been characterized in vitro and in vivo for inhibition of dipeptidyl peptidase IV and is supplied for laboratory research use.
- Inhibits dipeptidyl peptidase IV (DPP-IV) in vitro and in vivo.
- Reported IC50 values: purified rabbit DPP-IV 4.5 μM; rabbit plasma DPP-IV 30 μM.
- High reported purity (99.8%).
- Molecular formula C20H26ClN; molecular weight 315.9 g/mol.
- Intended for biochemical and pharmacological research use only.
- Available in small research pack sizes suitable for assay work.
![Medchemexpress LLC Acetamide, N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]- | 893990-34-6 | MFCD05957363 | 99.7% | 342.44 | C16H14N4OS2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000289016.png-250.jpg)
Medchemexpress LLC Acetamide, N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]- | 893990-34-6 | MFCD05957363 | 99.7% | 342.44 | C16H14N4OS2 | 10 MG
VU 0240551 is a small-molecule research compound that acts as a potent neuronal K+-Cl- cotransporter 2 (KCC2) inhibitor and is used in in vitro pharmacology and preclinical studies. It shows submicromolar activity at KCC2 and selectivity versus NKCC1.
- Potent KCC2 inhibitor (IC50 ≈ 560 nM).
- Selective versus NKCC1 (IC50 > 50 μM).
- High purity (99.7%).
- Molecular weight 342.44; formula C16H14N4OS2.
- White to off-white solid with high solubility in DMSO (≥ 50 mg/mL).
- Recommended storage: powder -20 °C (long-term) or 4 °C (shorter term); solvent storage at -80 °C.
- Supplied in small pack sizes suitable for research (5 mg-100 mg).