Hydrochlorides
Medchemexpress LLC 4-hydroxy-L-proline methyl ester hydrochloride | 40216-83-9 | MFCD00080855 | >97.0% | 181.62 | C6H12ClNO3 | 1 KG
H-Hyp-OMe hydrochloride is the methyl ester hydrochloride of trans-4-hydroxy-L-proline, used as a building block and non-cleavable linker in organic synthesis and bioconjugation.
- Used as a linker or building block in antibody-drug conjugate and PROTAC synthesis.
- Methyl ester hydrochloride form facilitates coupling reactions in organic synthesis.
- Available in bulk quantities suitable for scale-up reactions.
- Stable when stored sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
- Reported purity meets typical requirements for synthetic applications.
Medchemexpress LLC Harmalol hydrochloride | 6028-07-5 | 99.9% | 236.70 g/mol | C12H13ClN2O | 10 MG
Harmalol hydrochloride is the hydrochloride salt of harmalol, a beta-carboline alkaloid supplied for research use. It is reported to inhibit dioxin-mediated induction of CYP1A1 and to exhibit antioxidant and hydroxyl radical-scavenging activity.
- High purity: 99.91%.
- Hydrochloride salt form, solid, suitable for biochemical and pharmacological studies.
- Molecular formula C12H13ClN2O; molecular weight 236.70 g/mol.
- Provided in small research quantities appropriate for assay development and analytical testing.
- Store sealed at 4°C, protected from moisture and light; in solution store at -80°C (6 months) or -20°C (1 month).
Sigma Aldrich Fine Chemicals Biosciences o-Phenylenediamine dihydrochloride tablet, 15 mg substrate per tablet | 615-28-1 | MFCD00012966 | 50TAB
o-Phenylenediamine dihydrochloride tablet, 15 mg substrate per tablet | Mol Wt: 181.06 | 615-28-1 | MFCD00012966 | 50TAB
Medchemexpress LLC Zt 52656a hydrochloride | 115730-24-0 | MFCD00673899 | 100.0% | 390.87 g·mol⁻¹ | C19H26ClF3N2O | 100 MG
ZT 52656A hydrochloride is the hydrochloride salt of a selective kappa opioid receptor agonist used in research to investigate kappa-mediated analgesia and the prevention or alleviation of ocular pain. Supplied as a white to off-white solid for laboratory applications, it is intended for research use only and not for clinical or human use.
- Selective kappa opioid receptor agonist.
- High reported purity (99.98%).
- Molecular weight 390.87 g·mol⁻¹.
- White to off-white solid suitable for analytical and in vivo studies.
- Recommended storage: 4°C sealed; in solvent: -80°C up to 6 months, -20°C up to 1 month.
- Available in multiple package sizes, including 100 mg.
Sigma Aldrich Fine Chemicals Biosciences O-Benzylhydroxylamine hydrochloride 99% | 2687-43-6 | MFCD00012952 | 5G
O-Benzylhydroxylamine hydrochloride 99% | Purity: 99% | Mol Wt: 159.61 | 2687-43-6 | MFCD00012952 | 5G
Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 99.9% | 260.72 g/mol | C11H17ClN2O3 | 100 MG
Nifenalol hydrochloride is a research-grade β-adrenergic receptor antagonist (hydrochloride salt) used in pharmacology and cardiac electrophysiology studies. It is provided as a high-purity solid for biochemical and cellular assays, with recommended storage and solvent stability guidance supplied by the manufacturer.
- Chemical identity: CAS number 5704-60-9; formula C11H17ClN2O3; molecular weight 260.72 g/mol.
- Primary activity: β-adrenergic receptor antagonist demonstrating early afterdepolarization effects.
- High purity: 99.9% as listed by manufacturer.
- Available formats: solid and solution stocks, sold in multiple sizes including 100 MG.
- Storage recommendation: sealed, away from moisture and light; solids refrigerated at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
Sigma Aldrich Fine Chemicals Biosciences 4-Methylmorpholine BioXtra, suitable for protein sequencing, >=99.5% (GC) | 109-02-4 | MFCD00006175 | 500ML
4-Methylmorpholine BioXtra, suitable for protein sequencing, >=99.5% (GC) | Purity: >=99.5% (GC) | Mol Wt: 101.15 | 109-02-4 | MFCD00006175 | 500ML
Medchemexpress LLC Vu 0365114 | 1208222-39-2 | 99.4% | 397.35 g·mol⁻1 | C22H14F3NO3 | 100 MG
VU 0365114 is a small-molecule selective positive allosteric modulator of the muscarinic acetylcholine receptor M5 for research use. It potentiates acetylcholine-stimulated responses in cellular assays and has been reported to increase insulin secretion in human β-cells. Reported potency is micromolar with minimal activity at M1-M4.
- Selective mAChR M5 positive allosteric modulator with EC50 ~1.6-2.7 μM.
- Demonstrated increase of acetylcholine-stimulated insulin secretion in human β-cells.
- High purity approximately 99.4%.
- Solid, light yellow to orange appearance.
- Molecular formula C22H14F3NO3; molecular weight 397.35 g·mol⁻1.
- Powder stable at -20°C for extended storage.
Medchemexpress LLC Lobeline hydrochloride | 134-63-4 | 99.9% | 5 MG
Lobeline (α-Lobeline) hydrochloride is a brain-penetrant nicotinic receptor agonist. It increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles and altering presynaptic DA storage. Lobeline hydrochloride is effective in smoking cessation.
- Evokes [3H]DA overflow calcium-independently
- Inhibits [3H]DA uptake into synaptosomes and vesicles
- Decreases d-methamphetamine self-administration in rats
- Increases tolerance development to d-methamphetamine
Medchemexpress LLC SB-399885 hydrochloride | 402713-81-9 | MFCD09970355 | 98.3% | 482.81 g·mol⁻¹ | C18H22Cl3N3O4S | 50 MG
SB-399885 hydrochloride is the hydrochloride salt of SB-399885, a selective 5-HT6 (serotonin 6) receptor antagonist supplied for research use. It is provided as a high-purity solid and is available as a ready-to-use solution in DMSO, for use in in vitro and in vivo pharmacological studies.
- Selective 5-HT6 receptor antagonist.
- High reported purity (~98.3%).
- Hydrochloride salt form for improved stability and solubility.
- Available as solid and 10 mM solution in DMSO.
- Suitable for in vitro and in vivo pharmacology studies.
Medchemexpress LLC SB 202190 hydrochloride | 350228-36-3 | MFCD17215958 | ≥98.0% | 367.8 g/mol | C20H15ClFN3O | 100 MG
SB 202190 hydrochloride is a selective inhibitor of p38 mitogen-activated protein kinases used in research to probe p38α/β signaling pathways. It is supplied as the monohydrochloride salt in crystalline form and is intended for research use only.
- Selective p38α and p38β inhibitor with IC50 values of 50 nM and 100 nM.
- High affinity binding to the p38 ATP pocket (Kd ≈ 38 nM).
- Molecular weight approximately 367.8 g/mol.
- Empirical formula: C20H15ClFN3O (hydrochloride salt).
- Physical form: crystalline solid; storage at -20°C; in solution store at -80°C for long-term.
- For research use only; not for human or veterinary use.
Selleck Chemical LLC Tirofiban S3085-25mg
Tirofiban (MK-383) is a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM
Medchemexpress LLC XE991 dihydrochloride | 122955-13-9 | 99.6% | 449.37 | 10 MG
XE991 dihydrochloride is a Kv7 (KCNQ) channels blocker. It potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current with IC50s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively. This compound is designed for research applications.
- Potent Kv7 (KCNQ) channels blocker
- Inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current
- Enhances [3H]ACh release from rat brain slices with an EC50 of 490 nM
- Demonstrates good in vivo potency and duration of action
- For research use only
Sigma Aldrich Fine Chemicals Biosciences 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride powder | 23007-85-4 | MFCD00012790 | 100MG
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride powder | Mol Wt: 209.72 | 23007-85-4 | MFCD00012790 | 100MG