Hydrochlorides
Medchemexpress LLC Tirofiban | 144494-65-5 | 440.60 | 5 MG
Tirofiban is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist. It inhibits fibrinogen binding to this receptor, providing antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cells by stimulating VEGF production. It can significantly reduce myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.
- Selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist
- Inhibits fibrinogen binding
- Provides antithrombotic activity
- Induces endothelial cell proliferation and migration
- Stimulates vascular endothelial growth factor (VEGF) production
- Reduces myocardial no-reflow
- Alleviates myocardial microvascular structural and endothelial dysfunction
- Targets integrin
- Affects cytoskeleton pathway
Medchemexpress LLC Piperoxan hydrochloride | 135-87-5 | MFCD00079224 | 99.7% | 269.77 | C14H20ClNO2 | 5 MG
Piperoxan hydrochloride is a small-molecule research reagent described as an α2 adrenoceptor antagonist and a first-generation antihistamine. Supplied as the hydrochloride salt (CAS 135-87-5), it is used in pharmacology and receptor-binding studies to probe adrenergic and histaminergic mechanisms.
- High purity research-grade small molecule (molecular weight 269.77).
- Acts as an α2 adrenoceptor antagonist for receptor pharmacology studies.
- Exhibits first-generation antihistamine properties relevant to histamine assays.
- Available in milligram-scale quantities suitable for in vitro research.
- Provided with SDS and COA documentation for handling and quality assurance.
Medchemexpress LLC 3-Pyridylacetic acid hydrochloride | 6419-36-9 | 173.60 | 1 ML
3-Pyridylacetic acid hydrochloride is a high homolog of nicotinic acid and a decomposition product of nicotine (and other tobacco alkaloids). It can be used to synthesize anti-inflammatory agents or as a precursor for the preparation of herbicides.
- Used to synthesize anti-inflammatory agents
- Precursor for the preparation of herbicides
Medchemexpress LLC Prodipine hydrochloride | 31314-39-3 | 99.8% | 315.9 g/mol | C20H26ClN | 10 MG
Prodipine hydrochloride is a diphenyl-phosphonate derivative used as a research DPP-IV inhibitor. It has been characterized in vitro and in vivo for inhibition of dipeptidyl peptidase IV and is supplied for laboratory research use.
- Inhibits dipeptidyl peptidase IV (DPP-IV) in vitro and in vivo.
- Reported IC50 values: purified rabbit DPP-IV 4.5 μM; rabbit plasma DPP-IV 30 μM.
- High reported purity (99.8%).
- Molecular formula C20H26ClN; molecular weight 315.9 g/mol.
- Intended for biochemical and pharmacological research use only.
- Available in small research pack sizes suitable for assay work.
![Medchemexpress LLC Acetamide, N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]- | 893990-34-6 | MFCD05957363 | 99.7% | 342.44 | C16H14N4OS2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000289016.png-250.jpg)
Medchemexpress LLC Acetamide, N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]- | 893990-34-6 | MFCD05957363 | 99.7% | 342.44 | C16H14N4OS2 | 10 MG
VU 0240551 is a small-molecule research compound that acts as a potent neuronal K+-Cl- cotransporter 2 (KCC2) inhibitor and is used in in vitro pharmacology and preclinical studies. It shows submicromolar activity at KCC2 and selectivity versus NKCC1.
- Potent KCC2 inhibitor (IC50 ≈ 560 nM).
- Selective versus NKCC1 (IC50 > 50 μM).
- High purity (99.7%).
- Molecular weight 342.44; formula C16H14N4OS2.
- White to off-white solid with high solubility in DMSO (≥ 50 mg/mL).
- Recommended storage: powder -20 °C (long-term) or 4 °C (shorter term); solvent storage at -80 °C.
- Supplied in small pack sizes suitable for research (5 mg-100 mg).
Medchemexpress LLC Anabasine ((S)-Anabasine) | 494-52-0 | MFCD00006370 | 99.0% | 50 MG
Anabasine is an alkaloid found as a minor component in tobacco (Nicotiana). It is a botanical pesticide that acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM).
- Found in tobacco (Nicotiana)
- Acts as a full agonist of nicotinic acetylcholine receptors
- Induces depolarization of TE671 cells
- Molecular weight: 162.24
- Formula: C10H14N2
- Appearance: Liquid (Density: 1.0455 g/cm3)
- Colorless to light yellow liquid
- Storage: 4°C, protect from light
Medchemexpress LLC GSK-LSD1 dihydrochloride | 2102933-95-7 | 99.5% | 289.24 g·mol⁻1 | C14H22Cl2N2 | 50 MG
This dihydrochloride salt is a potent, selective, and irreversible inhibitor of lysine-specific demethylase 1 (LSD1), used as a research probe for epigenetic regulation and metabolic studies. It exhibits an IC50 of 16 nM and is supplied with high reported purity.
- Potent LSD1 inhibition with IC50 of 16 nM.
- High purity (≈99.5%).
- Supplied as a dihydrochloride salt in solid and DMSO solution formats.
- Suitable for epigenetic and metabolic research applications.
- Available in small research pack sizes including 50 MG.
Medchemexpress LLC Tirofiban (hydrochloride monohydrate) | 150915-40-5 | 99.9% | 495.07 | 1 ML
Tirofiban (hydrochloride monohydrate) | 150915-40-5 | 99.9% | 495.07 | 1 ML
Medchemexpress LLC Vu 0255035 | 1135243-19-4 | 99.8% | 432.52 g·mol⁻¹ | C18H20N6O3S2 | 1 ML
VU 0255035 is a selective, competitive antagonist of the muscarinic M1 receptor supplied for research use. It is available as a high-purity solid and as a ready-to-use 10 mM solution in DMSO, supporting receptor pharmacology experiments, selectivity profiling, and dose-response studies.
Medchemexpress LLC Rs-127445 hydrochloride | 199864-86-3 | 99.8% | 317.79 g·mol⁻¹ | C17H17ClFN3 | 10 MG
RS-127445 hydrochloride is a selective, high-affinity 5-HT2B receptor antagonist (pKi ≈ 9.5) provided as a research-grade chemical. It shows approximately 1,000-fold selectivity versus other receptors and is supplied as a solid (powder) or as a ready-to-use 10 mM solution in DMSO. Intended for research use only.
Medchemexpress LLC Anabasine ((S)-Anabasine) | 494-52-0 | 99.0% | 5 MG
Anabasine ((S)-Anabasine) is an alkaloid found as a minor component in tobacco (Nicotiana). It acts as a botanical pesticide nicotine and is a full agonist of nicotinic acetylcholine receptors (nAChRs). It induces depolarization of TE671 cells that endogenously express human fetal muscle-type nAChRs (EC50=0.7 μM).
- Found as a minor component in tobacco
- Acts as a botanical pesticide
- Full agonist of nicotinic acetylcholine receptors (nAChRs)
- Induces depolarization of TE671 cells
Medchemexpress LLC Vasicine hydrochloride | 7174-27-8 | 224.69 | 1 MG
Vasicine hydrochloride is a quinazoline alkaloid isolated from Justicia adhatoda. It activates the PI3K/Akt signaling pathway and demonstrates antioxidant, anti-inflammatory, and antibacterial activities. In vitro, it shows moderate inhibitory activity against H+/K+-ATPase and scavenges DPPH free radicals. In vivo studies indicate it improves cardiac function and alleviates myocardial necrosis in rat models of myocardial infarction.
- Activates PI3K/Akt signaling pathway.
- Exhibits antioxidant activity.
- Demonstrates anti-inflammatory effects.
- Possesses antibacterial properties.
- Inhibits H+/K+-ATPase.
- Scavenges DPPH free radicals.
- Reduces gastric acid secretion.
- Has anti-ulcer effects.
- Improves cardiac function in myocardial infarction models.
- Inhibits myocardial cell apoptosis.
![Medchemexpress LLC 1-[1-(4-methoxyphenyl)-2-(methylamino)ethyl]cyclohexan-1-ol hydrochloride | 93413-90-2 | 99.6% | 299.83 g/mol | C16H26ClNO2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000263991.png-250.jpg)
Medchemexpress LLC 1-[1-(4-methoxyphenyl)-2-(methylamino)ethyl]cyclohexan-1-ol hydrochloride | 93413-90-2 | 99.6% | 299.83 g/mol | C16H26ClNO2 | 5 MG
High-purity hydrochloride salt of N-desmethyl venlafaxine used as a reference standard for analytical chemistry, impurity profiling, and method development in research laboratories.
- Purity ~99.6%.
- Molecular weight 299.83 g/mol.
- Chemical formula C16H26ClNO2.
- CAS number 93413-90-2.
- Supplied in small-quantity vials suitable for reference standard use.
- Intended for analytical and impurity identification applications.
Medchemexpress LLC ASP-4058 hydrochloride | 952510-14-4 | 99.7% | 478.78 | 25 MG
ASP-4058 hydrochloride is a next-generation, selective, and orally active agonist for Sphingosine 1-Phosphate receptors 1 and 5 (S1P1 and S1P5). This compound has been shown to ameliorate rodent experimental autoimmune encephalomyelitis with a favorable safety profile.
- Next-generation S1P1 and S1P5 agonist
- Selective and orally active
- Ameliorates rodent experimental autoimmune encephalomyelitis
- Favorable safety profile
Medchemexpress LLC VU 0364439 | 1246086-78-1 | C18H13Cl2N3O3S | 1 MG
VU 0364439 is a mGlu4 positive allosteric modulator (PAM) with an EC50 of 19.8 nM. It is for research use only. The compound shows better stability in HLM (63% remaining) than RLM (2% remaining). It is a positive allosteric modulator of human mGlu4 receptor expressed in CHO cells, assessed as potentiation of glutamate-induced calcium mobilization. The appearance is a solid, white to off-white.
- Positive allosteric modulator of human mGlu4 receptor
- EC50 of 19.8 nM
- Better stability in HLM (63% remaining) than RLM (2% remaining)
- Appearance: Solid, white to off-white
- For research use only