Heptane
Medchemexpress LLC Sappanchalcone | 94344-54-4 | 99.5% | C16H14O5 | 5 MG
Sappanchalcone is a flavonoid isolated from *Caesalpinia sappan L.*, which induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells. It is intended for research use only.
- Flavonoid isolated from *Caesalpinia sappan L.*
- Induces caspase-dependent and AIF-dependent apoptosis
- Shows statistically significant effect on HCT116 cells
- Reduces MMP with significant increase in ROS levels
- Triggers phosphorylation of p53
- Inhibits LPS stimulated TNF alpha production in Balb/c mouse peritoneal macrophages
Medchemexpress LLC 3'-Hydroxypuerarin | 117060-54-5 | 432.38 | 20 MG
3'-Hydroxypuerarin is an isoflavone isolated from the roots of Pueraria lobata (Willd.) Ohwi. It acts as an antioxidant, exhibiting marked ONOO(-), NO•, and total ROS scavenging activities.
- Isolated from Pueraria lobata (Willd.) Ohwi.
- Acts as an antioxidant.
- Exhibits marked ONOO(-) scavenging activity.
- Exhibits marked NO• scavenging activity.
- Exhibits marked total ROS scavenging activities.
Medchemexpress LLC 1h-isoindole-1,3(2h)-dione, 2-[2-(3,4-dihydro-2,2,4-trimethyl-1(2h)-quinolinyl)-2-oxoethyl]- | 332382-54-4 | 99.4% | 362.42 | 10 MG
ML-SA1 is a selective TRPML agonist that inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. It induces autophagy and can be used for research as a broad-spectrum antiviral.
- Selective TRPML agonist
- Inhibits dengue virus 2 (DENV2) and zika virus (ZIKV)
- Promotes lysosomal acidification and protease activity
- Induces autophagy
- Broad-spectrum antiviral research
Medchemexpress LLC Az506 | 2043321-54-4 | 99.7% | C33H40N6O | 10MG
AZ506 is a small-molecule inhibitor of the lysine methyltransferase SMYD2. It shows potent biochemical activity (SMYD2 IC50 = 17 nM) and reduces SMYD2-mediated p53 methylation in cells (cellular IC50 = 2.43 μM). The compound is supplied as solids in multiple sizes and as a 10 mM solution in DMSO for biochemical and cellular research applications.
- Potent SMYD2 inhibition with low nanomolar biochemical potency.
- Demonstrated cellular activity reducing p53 methylation.
- High purity suitable for research applications (99.7%).
- Available as solids in multiple sizes and as a ready-to-use DMSO solution.
- Provided with safety and data documentation for laboratory use.
Medchemexpress LLC MID-1 25mg | 312608-54-1 | 25 MG
MID-1 is a small-molecule research compound that disrupts the interaction between MG53 and IRS-1, preventing MG53-induced ubiquitination and degradation of IRS-1 and thereby increasing IRS-1 levels and insulin signaling in muscle cells. Supplied as an orange to red solid for laboratory research.
- Disrupts MG53-IRS-1 interaction
- Enhances IRS-1 expression and insulin signaling
- High purity for reliable assay performance
- Orange to red solid with good DMSO solubility
- Suitable for in vitro studies of insulin signaling and glucose uptake
![eMolecules 22767-50-6 | Sodium heptane-1-sulfonate | ChemScene204.260 | C7H17NaO3S | 97.000 | [NaH].CCCCCCCS(O)(=O)=O | 25g | 844789771](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000483339.jpg-250.jpg)
eMolecules 22767-50-6 | Sodium heptane-1-sulfonate | ChemScene204.260 | C7H17NaO3S | 97.000 | [NaH].CCCCCCCS(O)(=O)=O | 25g | 844789771
Sodium heptane-1-sulfonate | ChemScene | 22767-50-6204.260 | C7H17NaO3S | 97.000 | [NaH].CCCCCCCS(O)(=O)=O | 25g | 844789771
![Medchemexpress LLC Acetamide, N-[3-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl] | 1401731-54-1 | 99.8% | 266.30 g·mol⁻¹ | C15H14N4O | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000227822.png-250.jpg)
Medchemexpress LLC Acetamide, N-[3-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl] | 1401731-54-1 | 99.8% | 266.30 g·mol⁻¹ | C15H14N4O | 50 MG
N-(3-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl)acetamide is a research-grade small-molecule inhibitor of casein kinase 1 (CK1) and checkpoint kinase 1 (CHK1), supplied as a solid for laboratory research use. It has CAS 1401731-54-1, molecular formula C15H14N4O, molecular weight 266.30 g·mol⁻¹, and reported purity of 99.77%.
- High chemical purity suitable for biochemical and cellular assays.
- Solid form enables straightforward handling and storage.
- Targets CK1 and CHK1 for kinase pathway studies.
- Available in small research quantities for assay development.
Medchemexpress LLC C18H14Cl2F2N4O2S | 2505339-54-6 | MFCD34565708 | 99.8% | 459.30 | C18H14Cl2F2N4O2S | 5 MG
This selective small-molecule inhibitor targets fibroblast activation protein (FAP) and is intended for research use. It exhibits potent FAP inhibition in vitro (IC50 = 2 nM), shows dose-dependent activity in animal studies, and is supplied as a high-purity solid with defined storage recommendations.
- Selective fibroblast activation protein inhibitor with IC50 of 2 nM.
- Also inhibits prolyl oligopeptidase with lower potency (IC50 ≈ 49 μM).
- High purity, ≥99.82% by HPLC.
- Molecular weight 459.30 g/mol and formula C18H14Cl2F2N4O2S.
- Appearance: white to off-white solid.
- Storage: keep sealed, away from moisture and light; in solvent -80°C (6 months), -20°C (1 month).
- Supplied as a small quantity suitable for in vitro and in vivo research.
- For research use only; not for human or diagnostic use.
Medchemexpress LLC Cyclosomatostatin | 84211-54-1 | 99.8% | 779.97 | 1 MG
Cyclosomatostatin is a potent somatostatin (SST) receptor antagonist. It can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size, and sphere-formation in colorectal cancer (CRC) cells.
- Potent somatostatin (SST) receptor antagonist
- Inhibits somatostatin receptor type 1 (SSTR1) signaling
- Decreases cell proliferation
- Decreases ALDH+ cell population size
- Decreases sphere-formation in colorectal cancer (CRC) cells
- Target for somatostatin receptor
- Involved in GPCR/G protein and neuronal signaling pathways
![Medchemexpress LLC 2-cyano-N-{[(3,4-dichlorophenyl)carbamothioyl]amino}acetamide | 656222-54-7 | MFCD00119122 | 99.8% | 303.17 g/mol | C10H8Cl2N4OS | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235492.png-250.jpg)
Medchemexpress LLC 2-cyano-N-{[(3,4-dichlorophenyl)carbamothioyl]amino}acetamide | 656222-54-7 | MFCD00119122 | 99.8% | 303.17 g/mol | C10H8Cl2N4OS | 100MG
iKIX1 is an antifungal research compound that resensitizes drug-resistant Candida glabrata to azole antifungals by inhibiting the interaction between the KIX domain of mediator subunit CgGal11A and the activation domain of CgPdr1. It is used for in vitro studies of multidrug resistance and fungal infection models.
- Molecular formula: C10H8Cl2N4OS.
- Molecular weight: 303.17 g/mol.
- Purity: 99.8% (HPLC).
- Appearance: off-white to light yellow solid.
- Solubility: DMSO 83.33 mg/mL (≈274.9 mM); may require ultrasonic.
- Storage: powder -20°C (up to 3 years); in solution -80°C (6 months), -20°C (1 month).
- Available sizes: solid quantities from milligram to gram scale and 10 mM solutions in DMSO.
Medchemexpress LLC Zanzalintinib | 2367004-54-2 | 99.91% | 528.53 | 50 MG
Zanzalintinib (XL092) is an orally active, ATP-competitive inhibitor of multiple receptor tyrosine kinases (RTKs) including MET, VEGFR2, AXL, and MER. It exhibits anti-tumor activity and has potential for research in kinase-dependent diseases and conditions.
- Orally active, ATP-competitive inhibitor
- Targets MET, VEGFR2, AXL, and MER
- Exhibits anti-tumor activity
- Potential for kinase-dependent diseases and conditions research
Sigma Aldrich Fine Chemicals Biosciences Heptane suitable for HPLC
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. Heptane is an environmentally preferable solvent and greener alternative to hexane for chromatographic purification and thus has been enhanced for Safer Solvents and Auxiliaries. Click here for more information.Tools and techniques for solvent selection green solvent selection guides.Heptane (n-Heptane) is a linear hydrocarbon. Its cetane number has been reported to be 56.
Medchemexpress LLC Sodium heptane-1-sulfonate | 22767-50-6 | MFCD00007543 | 98.0% | 202.25 g·mol⁻¹ | C7H15NaO3S | 10 G
Sodium heptane-1-sulfonate is the sodium salt of heptane-1-sulfonic acid used as an ion-pairing reagent and buffer additive for biochemical research and reversed-phase HPLC separations. It is a water-soluble sulfonate that helps improve chromatographic retention and peak shape for ionic and polar analytes.