Tetrahydrofuran
Medchemexpress LLC CIL62 | 117593-36-9 | 97.0% | 382.45 | 50 MG
CIL62 is a caspase-3/7-independent cell death inducer that operates via Necrostatin-1 dependent mechanisms. It exhibits antiproliferative activity against human COLO205, IMR32, and K562 cells.
- Caspase-3/7-independent cell death inducer
- Necrostatin-1 dependent mechanism of action
- Antiproliferative activity against COLO205, IMR32, and K562 cells
Medchemexpress LLC N'-(4-(diethylamino)-2-hydroxybenzylidene)isonicotinohydrazide | 140405-36-3 | MFCD00542031 | 99.7% | 312.37 g/mol | C17H20N4O2 | 10 MG
RSVA405 (CAS 140405-36-3) is a small-molecule activator of AMP-activated protein kinase (AMPK) used in cellular and biochemical research. It promotes CaMKKβ-dependent AMPK activation, inhibits mTOR signaling, and can induce autophagy; supplied at high purity for research applications.
- Potent AMPK activator; reported EC50 = 1 μM.
- High purity (~99.7%).
- Molecular formula C17H20N4O2; molecular weight 312.37 g/mol.
- Soluble in DMSO; available as solid or DMSO solution.
- For research use only; not for human consumption.
Medchemexpress LLC Broflanilide (Standard) | 1207727-04-5 | 98% | 663.28 | 50 MG
Broflanilide (Standard) | 1207727-04-5 | 98% | 663.28 | 50 MG
Chemscene ChemScene | (R)-Tetrahydrofuran-2-yl-methylamine | 10G | CS-W011317 | 0.98 | 7202-43-9| MFCD00192476 | 101.15
ChemScene | (R)-Tetrahydrofuran-2-yl-methylamine | 10G | CS-W011317 | 0.98 | 7202-43-9| MFCD00192476 | 101.15
Medchemexpress LLC Cleistanthin B | 30021-77-3 | 98.2% | 542.49 | 1 MG
Cleistanthin B is an orally active arylnaphthalene lignan lactone glycoside that demonstrates anti-SARS-CoV-2 effects in Vero cells and exhibits antitumor, diuretic, and antihypertensive properties in vivo.
- Exhibits anti-SARS-CoV-2 effects in Vero cells with an EC50 of 6.51 μM
- Shows no cytotoxicity to Vero cells in concentrations up to 100 μM
- Demonstrates antitumor activity against EAC and DAL tumor mice
- Also shows diuretic and antihypertensive effects
Medchemexpress LLC Rhamnocitrin | 569-92-6 | 300.26 | 5 MG
Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3, and MAPK pathways. It selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons by regulating miR-185, STIM-1, NFATc3, and ERK/p38 MAPK pathways. It can be used in the study of endothelial-related inflammatory diseases and neuroprotection.
- Functions as an anti-inflammatory and antioxidant agent.
- Targets STIM-1, NFATc3, and MAPK pathways.
- Inhibits oxidative stress and inflammatory responses.
- Useful for studying endothelial-related inflammatory diseases.
- Useful for neuroprotection research.
Medchemexpress LLC Tabersonine | 4429-63-4 | MFCD28140545 | 336.43 | 50 MG
Tabersonine | 4429-63-4 | MFCD28140545 | 336.43 | 50 MG
Medchemexpress LLC Ro5-3335 | 30195-30-3 | 99.5% | 259.69 | 10 MG
Ro5-3335 | 30195-30-3 | 99.5% | 259.69 | 10 MG
Medchemexpress LLC Tienilic acid (Ticrynafen) | 40180-04-9 | 99.7% | 331.18 | 5 MG
Tienilic acid (Ticrynafen; ANP 3624) acts as a diuretic hypotensive agent, but it induces hepatotoxicity. It is converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro.
- Functions as a diuretic hypotensive agent.
- Known to induce hepatotoxicity.
- Converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro.
Medchemexpress LLC Metsulfuron-methyl (Standard) | 74223-64-6 | 50 MG
Metsulfuron-methyl (Standard) is the analytical standard of Metsulfuron-methyl. This product is intended for research and analytical applications. Metsulfuron-methyl is a systemic sulfonylurea herbicide that has been widely used to control broadleaf weeds and annual grasses in rice, corn, wheat, and barley. Metsulfuron-methyl exhibits high herbicidal activity and low mammalian toxicity, with an LD50 for rats exceeding 5000 mg/kg.
- The compound is the grade of analytical standard, which is the reference standard supplied assay.
- It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
eMolecules Medchem Express / (-)-Epiafzelechin / 5mg / 713705081 / HY-N0943 / / 24808-04-6 / MFCD20260428 / 274.272 / C15H14O5
Medchem Express / (-)-Epiafzelechin / 5mg / 713705081 / HY-N0943 / / 24808-04-6 / MFCD20260428 / 274.272 / C15H14O5
Medchemexpress LLC Kinase, Natto fermentation | 133876-92-3 | 27728 Da | 10 MG
Kinase, Natto fermentation is a potent fibrinolytic enzyme that breaks down blood clots by directly hydrolyzing fibrin and plasmin substrate. It is primarily used for cardiovascular disease research.
- Breaks down blood clots by directly hydrolyzing fibrin and plasmin substrate.
- Dissolves 94% of blood clots within ten minutes in vitro.
- Degrades fibrin clots after two hours of incubation in vitro.
- Exhibits fibrinolytic activity and dissolves blood clots in vivo.
- Stable in neutral or alkaline environments (pH 7.0-12.0).
- Stability improved when mixed with boiled rice extract, broth, serum protein, or gastric juice protein.
- Retains enzyme activity under acidic conditions with stabilizing agents.
- Better stability below 37°C.
- Retains 95% of original activity after 5 freeze-thaw cycles.
Medchemexpress LLC CIL62 | 117593-36-9 | 97.0% | 382.45 | 100 MG
CIL62 is a caspase-3/7-independent cell death inducer. Its mechanism of action is Necrostatin-1 dependent cell death.
- COLO 205: IC50 28 μM (Compound: 3f) for antiproliferative activity after 24 hrs by MTT assay.
- IMR-32: IC50 41 μM (Compound: 3f) for antiproliferative activity after 24 hrs by MTT assay.
- K562: IC50 36 μM (Compound: 3f) for antiproliferative activity after 24 hrs by MTT assay.
- Necrostatin-1 suppresses CIL62 at 19 μM (5 μg/mL).
Medchemexpress LLC (R)-Tetrahydrofuran-2-yl-methylamine | 7202-43-9 | ≥97.0% | 101.15 | 1 G
(R)-Tetrahydrofuran-2-yl-methylamine is a synthetic intermediate useful for pharmaceutical synthesis. It appears as a liquid, colorless to light yellow.
- Useful for pharmaceutical synthesis.
- Liquid appearance.
- Colorless to light yellow.
- For research use only.