Tetrahydrofuran
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran contains 2
Tetrahydrofuran (THf) is a widely used organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. The effect of THf on the biological systems has been studied.
Medchemexpress LLC Zectivimod | 1623066-63-6 | 99.4% | C28H31Cl2N3O3 | 10MG
Zectivimod is a sphingosine-1-phosphate (S1P) receptor agonist supplied for preclinical research into immune modulation, autoimmune disorders, and chronic inflammatory disease models. It is provided as a solid research chemical with solubility and formulation guidance for in vitro and in vivo studies.
- Acts as a sphingosine-1-phosphate receptor agonist for immunomodulation studies.
- High purity (≈99.4%) suitable for preclinical research.
- Available in multiple small-scale pack sizes for dosing and formulation work.
- Soluble in DMSO with explicit in vivo formulation protocols available.
- Storage and stability guidance provided for solid and solvent conditions.
Medchemexpress LLC GW406108X 100mg | 1644443-92-4 | 100 MG
GW406108X is a small-molecule research inhibitor that targets Kif15 (Kinesin-12) and ULK1, reported to inhibit autophagy via ATP-competitive inhibition of ULK1. Supplied as a solid, light yellow to yellow powder for laboratory research use only.
- Potent autophagy inhibitor: ULK1 pIC50 6.37 (≈427 nM); Kif15 ATPase IC50 0.82 μM.
- Specified purity: 98.0%.
- Molecular weight: 400.21 and formula C20H11Cl2NO4.
- Appearance: light yellow to yellow solid.
- Recommended storage: powder at -20°C for long term; in solvent, -80°C for up to 6 months.
- Available in multiple pack sizes including 100 mg.
Medchemexpress LLC Dalpiciclib 25mg | 1637781-04-4 | 25 MG
Dalpiciclib is a selective, orally active inhibitor of cyclin-dependent kinases 4 and 6 used in preclinical research to study cell-cycle regulation and anticancer activity. It is supplied as an off-white to light yellow solid with recommended storage and solubility handling for laboratory use.
- High purity for research applications.
- Molecular weight 446.54 g/mol and formula C25H30N6O2.
- Soluble in DMSO with recommended handling and warming.
- Stable when stored as powder at -20°C for long-term storage.
- For research use only; not for human or clinical use.
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran ReagentPlu
Tetrahydrofuran (THf) is a saturated cyclic ether mainly used as an organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. THf constitutes the key fragment of various natural products (polyether antibiotics). THf can form a double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1 4-diol is formed as an intermediate during the synthesis of THf. Hot THf is useful for the disSOLUTIONon of polyvinylidene chloride (PVDV).
Medchemexpress LLC Vebicorvir (ABI-H0731) | 2090064-66-5 | 99.7% | 467.44 g·mol^-1 | C19H12F3N3O4S2 | 5 MG
Vebicorvir (ABI-H0731) is a research-grade small-molecule inhibitor of the hepatitis B virus (HBV) core protein. It functions as a core protein allosteric modulator that suppresses formation of covalently closed circular DNA (cccDNA) in cellular infection models. For research use only.
- Inhibits HBV core protein via allosteric modulation.
- Suppresses cccDNA formation in cellular models (reported EC50 1.84-7.3 μM).
- High chemical purity suitable for biochemical and cellular assays.
- Molecular formula C19H12F3N3O4S2; molecular weight 467.44 g·mol^-1.
- Supplied as a solid, soluble in common organic solvents.
- For research use only; not for human or clinical use.
Medchemexpress LLC Erk1/2 inhibitor 2 (ASTX-029) | 2095719-92-7 | >98.0% | 584.04 g/mol | C29H31ClFN5O5 | 25MG
ASTX029 is a dual-mechanism extracellular signal-regulated kinase (ERK) 1/2 inhibitor developed as a clinical candidate. It inhibits ERK catalytic activity and ERK phosphorylation, with reported ERK2 IC50 ≈ 2.7 nM, and has demonstrated antineoplastic activity in preclinical models and early clinical evaluation. Supplied as a crystalline solid for research use, typical vendor-reported purity is ≥98% (CAS 2095719-92-7).
- Potent dual-mechanism ERK inhibitor with low-nanomolar potency.
- Inhibits both catalytic activity and phosphorylation of ERK.
- Demonstrated antineoplastic activity in preclinical and early clinical studies.
- Supplied as a crystalline solid suitable for in vitro and in vivo formulation.
- Typical purity ≥98% by vendor testing.
- CAS number 2095719-92-7 and molecular weight ≈584.04 g/mol.
- For research use only; not for human therapeutic use.
Medchemexpress LLC Liensinine perchlorate | 2385-63-9 | MFCD09953798 | 99.7% | 711.20 g/mol | C37H42N2O6·xHClO4 | 10 MG
Liensinine perchlorate is the perchlorate salt of liensinine, an alkaloid from Nelumbo nucifera supplied as a research reagent. It is used in vitro for biological studies and has reported anti-hypertensive and anti-cancer activities, including induction of apoptosis in colorectal cancer cells. Sold for research use only.
- High purity (99.67%).
- Available in small milligram quantities for screening and mechanistic studies.
- Perchlorate salt form improves solubility for biological assays.
- Identified by CAS number 2385-63-9 for unambiguous chemical reference.
- Handle with appropriate laboratory safety precautions; not for clinical use.
Medchemexpress LLC D-α-tocopherylquinone | 7559-04-8 | MFCD00135657 | 98.9% | 446.71 | C29H50O3 | 10 MG
- Oxidation product of α-tocopherol with quinone structure.
- Exhibits antioxidant and anticoagulant activity.
- Reduces oxidative damage from oxidized lipids.
- Interacts with glutathione-S-transferase (GST).
- Used in reactive oxygen species (ROS) and lipid peroxidation research.
- Molecular formula C29H50O3; MW 446.71 Da.
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran inhibitor-free, suitable for HPLC | 109-99-9 | MFCD00005356 | 4l
Tetrahydrofuran inhibitor-free, suitable for HPLC | Purity: 99.9% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 4l
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran | 109-99-9 | MFCD00005356 | 6x1l
Tetrahydrofuran | Purity: 99% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 6x1l
Medchemexpress LLC N'-(4-(diethylamino)-2-hydroxybenzylidene)isonicotinohydrazide | 140405-36-3 | MFCD00542031 | 99.7% | 312.37 | C17H20N4O2 | 100 MG
RSVA405 is a small-molecule activator of AMP-activated protein kinase (AMPK) that promotes CaMKKβ-dependent AMPK activation, inhibits mTOR signaling, enhances autophagy and Aβ degradation, and exhibits anti-inflammatory activity via STAT3 inhibition. It is used in metabolic, neurodegenerative, and obesity research.
- Potent AMPK activation and mTOR inhibition.
- Promotes autophagy and Aβ degradation.
- Reported anti-inflammatory activity through STAT3 inhibition.
- High purity (99.72%) suitable for research applications.
- Available as solid and as 10 mM solution in DMSO; multiple package sizes.
- Stable when stored as powder at -20°C and in solvent under recommended conditions.