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Filtered Search Results
Medchemexpress LLC Dalpiciclib 10mg | 1637781-04-4 | 10 MG
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Dalpiciclib is an orally active, selective cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor supplied for research use in a 10 mg vial. It is intended for preclinical and in vitro studies of cell-cycle regulation and anti-tumor activity.
- Selective CDK4/6 inhibitor used in preclinical research.
- Cas 1637781-04-4; molecular formula C25H30N6O2.
- Molecular weight 446.54 g/mol.
- Recommended storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent store at -80°C (6 months).
- Soluble in DMSO (50 mg/mL); manufacturer lists in vivo vehicle formulations for dosing.
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eMolecules 96-47-9 | 2-Methyltetrahydrofuran | Oakwood Chemicals | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 25g | 480143991
2-Methyltetrahydrofuran | Oakwood Chemicals | 96-47-9 | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 25g | 480143991
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Medchemexpress LLC Specnuezhenide ((8E)-Nuezhenide) | 39011-92-2 | 686.66 | 5 MG
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Specnuezhenide ((8E)-Nuezhenide) is a compound isolated from the fruits of *Ligustrum lucidum*. It demonstrates the ability to inhibit IL-1β-induced inflammation in chondrocytes by suppressing NF-κB and wnt/β-catenin signaling pathways. Additionally, Specnuezhenide exhibits anti-inflammatory effects in a rat model of osteoarthritis (OA).
- Isolated from *Ligustrum lucidum* fruits.
- Inhibits IL-1β-induced inflammation in chondrocytes.
- Exerts anti-inflammatory effects in osteoarthritis rat models.
- For research use only.
- Purity of 99.52%.
- Appears as a solid.
- Color is white to off-white.
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Medchemexpress LLC Methyl 3-{[(4-methylphenyl)sulfonyl]amino}benzoate | 173436-66-3 | 99.8% | 100MG
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Methyl 3-{[(4-methylphenyl)sulfonyl]amino}benzoate | 173436-66-3 | 99.8% | 100MG
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Medchemexpress LLC GW406108X 50mg | 1644443-92-4 | 400.21 | C20H11Cl2NO4 | 50 MG
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GW406108X (GW108X) is a small-molecule research inhibitor of Kif15 and ULK1 used in cellular and biochemical studies of mitosis and autophagy. It is supplied as a high-purity research chemical (CAS 1644443-92-4) with molecular formula C20H11Cl2NO4 and molecular weight 400.21.
- High purity (98.0%) suitable for biochemical and cellular assays.
- Reported activity against Kif15 and ULK1 for mechanistic studies.
- Known molecular weight and formula to support compound characterization.
- Supplied as a solid with good solubility in DMSO for stock preparation.
- Available in small pack sizes appropriate for research-scale experiments.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380505 HNRNPK-IN-1 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380449 R -PIRTOBRUTINIB 100MG
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Medchemexpress LLC Drinidene | 53394-92-6 | 99.0% | 5MG
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Drinidene | 53394-92-6 | 99.0% | 5MG
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Medchemexpress LLC Sx-682 CXCR1/2 inhibitor | 1648843-04-2 | 98.7% | 50MG
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Sx-682 CXCR1/2 inhibitor | 1648843-04-2 | 98.7% | 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000379059 AZ14145845 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380617 THIOL-C2-PEG2-OH 50MG
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Medchemexpress LLC Morphiceptin | 74135-04-9 | 99.1% | 521.61 | 1 MG
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Morphiceptin is a potent and specific agonist for morphine (μ) receptors. It is a synthetic peptide, derived from β-casein. It exhibits morphinelike activities and shows high specificity for morphine (μ) receptors, inhibiting the binding of [3H]dihydromorphine, 125I-labeled FK33824, and [3H]naloxone to rat brain membrane preparations with an IC50 of about 20 nM.
- Potent and specific agonist for morphine (μ) receptors
- Synthetic peptide derived from β-casein
- White to off-white solid appearance
- Soluble in water and DMSO
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Medchemexpress LLC N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide | 2922283-38-1 | 98.0% | C93H177N3O3 | 100 MG
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N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3 (HY-148049). TT3 is an ionizable lipid-like material used for mRNA delivery.
- Analogue of TT3, an ionizable lipid-like material for mRNA delivery.
- Available in various quantities.
- For research use only.
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Medchemexpress LLC TMX-4100 | 2367619-63-2 | 98.2% | C11H10N4O2S | 100 MG
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TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader. It demonstrates a high degradation preference for PDE6D with DC50 values less than 200 nM in MOLT4, Jurkat, and MM.1S cells. This compound can be utilized for research into multiple myeloma.
- Demonstrates a high degradation preference for PDE6D in MOLT4 cells.
- Exhibits better proteome-wide degradation selectivity in MOLT4 cells.
- Does not hinder the growth of KRAS-dependent cell lines.
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Medchemexpress LLC Acrylodan | 86636-92-2 | 95.1% | 225.29 g/mol | C15H15NO | 5 MG
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Acrylodan is a thiol-reactive, environment-sensitive fluorescent dye that covalently labels cysteine residues and reports on local dipolarity and conformational dynamics within binding pockets such as Cys34.
- Reacts with thiols to form a covalent fluorescent adduct.
- Sensitive to local dipolarity and protein dynamics.
- Soluble in DMSO at approximately 50 mg/mL; ultrasonic agitation may be required.
- Purity approximately 95.1%; molecular weight 225.29 g/mol.
- Store protected from light; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month).
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