Tetrahydrofuran
Medchemexpress LLC Phosphatidylinositols, soya, sodium salts | 383907-36-6 | 99.2% | 1 MG
Phosphatidylinositols, soya, sodium salts, is a mixture of phosphatidylinositols. Phosphoinositides are lipids involved in the vesicular transport of proteins and lipids between the different compartments of eukaryotic cells. They function by recruiting and/or activating effector proteins.
- Involved in regulating various cellular functions
- Regulates vesicular budding
- Regulates membrane fusion
- Regulates cytoskeleton dynamics
Medchemexpress LLC Specnuezhenide ((8E)-Nuezhenide) | 39011-92-2 | 686.66 | 5 MG
Specnuezhenide ((8E)-Nuezhenide) is a compound isolated from the fruits of *Ligustrum lucidum*. It demonstrates the ability to inhibit IL-1β-induced inflammation in chondrocytes by suppressing NF-κB and wnt/β-catenin signaling pathways. Additionally, Specnuezhenide exhibits anti-inflammatory effects in a rat model of osteoarthritis (OA).
- Isolated from *Ligustrum lucidum* fruits.
- Inhibits IL-1β-induced inflammation in chondrocytes.
- Exerts anti-inflammatory effects in osteoarthritis rat models.
- For research use only.
- Purity of 99.52%.
- Appears as a solid.
- Color is white to off-white.
![Medchemexpress LLC N,N'-1,3-phenylenebis[2,3-dihydroxy-benzamide] | 368449-04-1 | 98.6% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232665.png-250.jpg)
Medchemexpress LLC N,N'-1,3-phenylenebis[2,3-dihydroxy-benzamide] | 368449-04-1 | 98.6% | 50 MG
MST-312 (Telomerase Inhibitor IX) is a small-molecule telomerase inhibitor derived from epigallocatechin gallate (EGCG). It is supplied as a white to off-white solid for laboratory research in oncology and telomerase studies.
- Telomerase inhibitor for cancer research.
- Chemically modified derivative of epigallocatechin gallate (EGCG).
- Molecular formula C20H16N2O6 and molecular weight 380.35 g·mol⁻1.
- Purity 98.6%.
- Supplied as a solid with common solubility in DMSO for solution preparation.
Medchemexpress LLC N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide | 2922283-38-1 | 98.0% | C93H177N3O3 | 100 MG
N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3 (HY-148049). TT3 is an ionizable lipid-like material used for mRNA delivery.
- Analogue of TT3, an ionizable lipid-like material for mRNA delivery.
- Available in various quantities.
- For research use only.
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran contains 2
The product is tetrahydrofuran (THf) and it contains 250ppm BHT (Butylated hydroxytoluene) as an inhibitor. THf is widely employed as a solvent. It constitutes the key fragment of various natural products (polyether antibiotics). THf forms double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1 4-diol is formed as an intermediate during the synthesis of THf. Hot THf is useful for the disSOLUTIONon of polyvinylidene chloride (PVDV).
Sigma Aldrich Fine Chemicals Biosciences 2-Methyltetrahydrofuran BioRenewable, ReagentPlus(R), >=99.5%, contains 150-400 ppm BHT as stabilizer | 96-47-9 | MFCD00005367 | 4X4L
2-Methyltetrahydrofuran BioRenewable, ReagentPlus(R), >=99.5%, contains 150-400 ppm BHT as stabilizer | Purity: >=99.5% | Mol Wt: 86.13 | 96-47-9 | MFCD00005367 | 4X4L
Medchemexpress LLC Ambroxide | 6790-58-5 | 236.39 | 100 MG
Ambroxide is a naturally occurring terpenoid, known as a key constituent of ambergris. This compound is widely utilized in the manufacture of high-end perfumes to enhance aroma quality and extend fragrance lasting time.
- Naturally occurring terpenoid
- Key constituent of ambergris
- Utilized in high-end perfumes
- Enhances aroma quality
- Extends fragrance lasting time
- High purity (98.0%)
- Appears as a white to off-white solid
- Molecular formula: C16H28O
Medchemexpress LLC PF-00446687 free base | 862281-92-3 | 98.0% | 470.59 g/mol | C28H36F2N2O2 | 50 MG
PF-00446687 free base is a non-peptide, brain-penetrant small-molecule agonist of the melanocortin-4 receptor (MC4R) used in research on melanocortin signaling and central nervous system pharmacology. It is supplied as a powder for in vitro and in vivo studies and demonstrates low-nanomolar potency and selectivity.
- Selective melanocortin-4 receptor agonist with EC50 12 ± 1 nM.
- Binding affinity (Ki) approximately 27 ± 4 nM.
- Brain-penetrant, suitable for central nervous system studies.
- Provided as a powder with solubility in DMSO 62.5 mg/mL (ultrasonic recommended).
- Molecular formula C28H36F2N2O2 and molecular weight 470.59 g/mol.
- High purity by HPLC (≈98.0% per COA).
- Storage: powder -20°C (long-term) or 4°C (short-term).
Medchemexpress LLC Tienilic acid (Ticrynafen) | 40180-04-9 | 99.7% | 331.18 | 5 MG
Tienilic acid (Ticrynafen; ANP 3624) acts as a diuretic hypotensive agent, but it induces hepatotoxicity. It is converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro.
- Functions as a diuretic hypotensive agent.
- Known to induce hepatotoxicity.
- Converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro.
![eMolecules 959704-59-7 | TERT-BUTYL (1-OXASPIRO[2.5]OCTAN-6-YL)CARBAMATE | MFCD22377855 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502179564.JPG-250.jpg)
eMolecules 959704-59-7 | TERT-BUTYL (1-OXASPIRO[2.5]OCTAN-6-YL)CARBAMATE | MFCD22377855 | 1g
AstaTech | TERT-BUTYL (1-OXASPIRO[2.5]OCTAN-6-YL)CARBAMATE | 1g | 603096395 | W19422 | 95.000 | 959704-59-7 | MFCD22377855 | 227.304 | C12H21NO3
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Medchemexpress LLC Tabersonine | 4429-63-4 | MFCD28140545 | 336.43 | 50 MG
Tabersonine | 4429-63-4 | MFCD28140545 | 336.43 | 50 MG
Medchemexpress LLC VPC-70619 | 2361742-30-3 | 99.93% | C16H8ClF3N4O | 100 MG
VPC-70619 is a potent N-Myc inhibitor that blocks the binding of the N-Myc-Max heterocomplex to the DNA E-box and shows strong inhibitory activity against N-Myc-dependent cell lines. It can partially reverse paclitaxel resistance in cells by reducing MYCN expression and can be used for cancer research, including neuroblastoma and thyroid cancer.
- Potent N-Myc inhibitor
- Blocks the binding of the N-Myc-Max heterocomplex to the DNA E-box
- Shows strong inhibitory activity against N-Myc-dependent cell lines
- Partially reverses paclitaxel resistance by reducing MYCN expression
- Can be used for cancer research, including neuroblastoma and thyroid cancer
- Demonstrates high inhibition rates in certain cell types
- Highly stable in liver microsomes
- Regulates MYCN signaling pathway
- Inhibits proliferation, migration, and aggressiveness of cancer cells
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran | 109-99-9 | MFCD00005356 | 1 L
Tetrahydrofuran | Purity: ≥99.9% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 1 L
Sigma Aldrich Fine Chemicals Biosciences 2-Methyltetrahydrofuran BioRenewable, anhydrous, >=99%, Inhibitor-free | 96-47-9 | MFCD00005367 | 100ML
2-Methyltetrahydrofuran BioRenewable, anhydrous, >=99%, Inhibitor-free | Purity: >=99% | Mol Wt: 86.13 | 96-47-9 | MFCD00005367 | 100ML
Medchemexpress LLC Broflanilide | 1207727-04-5 | 99.0% | 663.28 | 100 MG
Broflanilide is an insecticide that converts into Desmethyl-Broflanilide, a powerful antagonist at the insect RDL GABA Receptor. This mechanism inhibits *S. litura* RDL GABAR with an IC50 of 1.3 nM. Desmethyl-Broflanilide shows limited activity against human GABAA α1β2γ2 receptor, mammalian GABAA α1β3γ2 receptor, and human glycine receptor (GlyR) α1β with IC50s greater than 3 μM, and less potent inhibition of GlyR α1-A288Gβ and GlyR α1-A288G (IC50s, 0.706, 0.149 μM).
- Acts as a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor.
- Inhibits *S. litura* RDL GABAR.
- Exhibits weak activity against human and mammalian GABAA receptors.
- Less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G.