Organic Acids
Medchemexpress LLC Guangxitoxin 1E TFA | ≥95.0% | 3948.61 | 100 UG
Guangxitoxin 1E TFA is the trifluoroacetate salt form of Guangxitoxin 1E, a peptide toxin. It functions as a potent and selective blocker of voltage-gated potassium channels KV2.1 and KV2.2, with an IC50 of 1-3 nM. This compound is intended for research purposes only and is not for human therapeutic use.
- Potent and selective blocker of KV2.1 and KV2.2 channels (IC50 of 1-3 nM)
- Inhibits KV4.3 channels (IC50 of 24-54 nM)
- Inhibits 90% of IDR in mouse β-cells
- Shifts voltage dependence of channel activation to more depolarized potentials
- Broadens β-cell action potential
- Enhances glucose-stimulated intracellular calcium oscillations
- Increases insulin secretion from mouse pancreatic islets in a glucose-dependent manner
eMolecules 2743-14-8 | Medchem Express | 11-Methoxyyangonin | 1mg | 536984971 | HY-N7207 | MFCD30544608 | 288.299 | C16H16O5
Medchem Express | 7-TFA-ap-7-Deaza-dG | 5mg | 719835964 | HY-138589 | 666847-77-4 | 415.329 | C16H16F3N5O5
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Medchemexpress LLC Mp6 (TFA) | 98.5% | 5 MG
mP6 (Myr-FEEERA-OH) is a myristoylated peptide and an integrin β3 inhibitor. It prevents the interaction of Gα13 with integrin β3 while preserving talin-dependent integrin function. This peptide also blocks the GTP usage of Rac1, Rap1, and Rab7, which effectively inhibits the infection of CHO-A24 cells.
- Myristoylated peptide
- Inhibits Gα13-integrin β3 interaction
- Preserves talin-dependent integrin function
- Blocks GTP usage of Rac1, Rap1, and Rab7
- Inhibits infection of CHO-A24 cells
- For research use only
Selleck Chemical LLC OT-82-5mg
OT-82 is a novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with average IC50s of 13.03 nM in non-HP cancer cells and 2.89 nM in HP cancer cells, respectively.
Medchemexpress LLC DPC-AJ1951 TFA | 99.4% | 1666.99 (free base) | 5 MG
This 14 amino acid peptide acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). Its activity has been characterized in ex vivo and in vivo assays of bone resorption.
- Potent agonist of parathyroid hormone (PTH)/PTH-related peptide receptor (PPR)
- Activity characterized in ex vivo and in vivo bone resorption assays
- Induces intracellular Ca2+ mobilization in HEK 293 cells transfected with human PPR
Medchemexpress LLC Peptide5 TFA | 98.9% | 1509.60 | 1 MG
A connexin 43 mimetic peptide, it reduces animal swelling, astrogliosis, and neuronal cell death after spinal cord injury. It also inhibits NLRP3 inflammasome, and is an anti-inflammatory agent.
- Reduces animal swelling after spinal cord injury.
- Reduces astrogliosis after spinal cord injury.
- Reduces neuronal cell death after spinal cord injury.
- Inhibits NLRP3 inflammasome.
- Acts as an anti-inflammatory agent.
Medchemexpress LLC Ala-MPSD TFA | 98.02% | 3016.76 | 5 MG
Ala-MPSD TFA is a control peptide for MPSD (HY-P10471). In Ala-MPSD TFA, the four serine residues of MPSD are substituted by alanines.
- Control peptide for MPSD (HY-P10471)
- Four serine residues of MPSD are substituted by alanines
- Molecular formula: C147H243N41O27.XC2HF3O2
- Sequence: Lys-Lys-Lys-Lys-Lys-Arg-Phe-Ala-Phe-Lys-Lys-Ala-Phe-Lys-Leu-Ala-Gly-Phe-Ala-Phe-Lys-Lys-Asn-Lys-Lys
- Purity: 98.02% (HPLC)
- Appearance: White to off-white (solid)
- MS consistent with structure
Medchemexpress LLC Wrwyar-NH2 TFA | 70.8% | 936.07 | 5 MG
Wrwyar-NH2 TFA is a control peptide primarily targeting DNA/RNA synthesis. It plays a role in the Cell Cycle/DNA Damage pathway. This product is intended for research use only and has not been fully validated for medical applications.
- Control peptide
- Targets DNA/RNA synthesis
- Involved in cell cycle/DNA damage pathway
- For research use only
Medchemexpress LLC Siivfekl (Tfa) | 99.9% | 948.16 | 5 MG
SIIVFEKL TFA is a variant of the major MHC class I-restricted epitope SIINFEKL. It is an antigenic peptide used in experimental settings to stimulate specific T cells and study competitive interactions. This peptide exhibits low affinity for the OT-I T cell receptor (TCR) and is suitable for CD8+ T cell detection.
- Antigenic peptide.
- Stimulates specific T cells.
- Exhibits low affinity for OT-I T cell receptor (TCR).
- Used for detection of CD8+ T cells.
- Soluble in H2O at ≥ 2 mg/mL.
eMolecules 16948-10-0 | Ambeed | 3-((tert-Butoxycarbonyl)amino)-2-methylpropanoic acid | 250mg | 531647313 | A185931 | MFCD02094137 | 203.238 | C9H17NO4
AstaTech | CEPHAPIRIN SODIUM | 1g | 443841839 | C74249 | 97.000 | 24356-60-3 | MFCD07793329 | 445.440 | C17H16N3NaO6S2
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Medchemexpress LLC ω-Agatoxin IVA TFA | 99.1% | 5316.27 | 100 UG
ω-Agatoxin IVA TFA is a potent, selective P/Q type Ca2+ (Cav2.1) channel blocker. It has IC50s of 2 nM for P-type and 90 nM for Q-type Ca2+ channels. It inhibits glutamate exocytosis and calcium influx elicited by high potassium (IC50, 30-225 nM), and blocks the high potassium-induced release of serotonin and norepinephrine. It has no effect on L-type or N-type calcium channels.
- Potent and selective P/Q type Ca2+ (Cav2.1) channel blocker
- Inhibits glutamate exocytosis and calcium influx
- Blocks high potassium-induced release of serotonin and norepinephrine
- Does not affect L-type or N-type calcium channels
Medchemexpress LLC JTP10-△-TATi TFA | 99.7% | 2833.28 | 5 MG
JTP10-△-TATi TFA is a selective JNK2 peptide inhibitor that exhibits 10-fold selectivity for JNK2 over JNK1 and JNK3. It has an IC50 of 92 nM for JNK2 and can inhibit the migration of PyVMTjnk2+/+ cells.
- Selective JNK2 peptide inhibitor
- IC50 of 92 nM for JNK2
- 10-fold selectivity over JNK1 and JNK3
- Inhibits migration of PyVMTjnk2+/+ cells