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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
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A polymethoxylated flavone isolated from citrus peels; inhibits signaling in cancer cells, reducing ERK signaling in T47D breast cancer cells (IC50 ~3 μM)
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Tangeretin (Tangeritin), a natural polymethoxylated flavone concentrated in the peel of citrus fruits, is known to have antiproliferative, antiinvasive, antimetastatic and antioxidant activities. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tangeretin (NSC-618905) a flavonoid from citrus fruit peels has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models and was also selected as a Notch-1 inhibitor. purity: 99%
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Myricetin, a natural flavonoid with antioxidant and anti tumor properties, is a novel inhibitor of MEK1 activity and transformation of JB6 P+ mouse epidermal cells. It also inhibits PI3K? with Kd of 0.17 ?M. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Kaempferol 3,7,4'-trimethyl ether is a flavonol aglycone isolated from the leaves of *Siparuna gigantotepala*. It exhibits antioxidant activity and is intended for research use only.
98.0% purity
Molecular weight: 328.32
Chemical formula: C18H16O6
Solid appearance
Light yellow to yellow color
Classified as a flavonoid, flavonol, phenol, and monophenol
Isolated from plants
Demonstrates cytotoxicity against human A549, HT-29, and HeLa cells
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Morin hydrate for microscopy (Fl.), for the determination of Al, Be, Zn, Ga, In, Sc, 1-2 mol/mol water | Purity: >=85% (HPLC) | 654055-01-3 | MFCD00017307 | 10G
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MW 491.7 Da. Microtubule-stabilizing agent. Epothilone A (ab143615) and B (ab141271) analog. Improves microtubule density and axonal integrity Shows antineoplastic and neuroprotective effects in vivo. Blood-brain barrier permeable.
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Epothilone D (189453-10-9) is a small-molecule microtubule-stabilizing agent It is designed to stabilize microtubules thereby disrupting essential cellular processes such as mitosis Epothilone D exerts its biological activity primarily through inhibition of microtubule depolymerization In in vitro assays Epothilone D demonstrates cytotoxic activity with IC50 values of 2 9 nM in MCF-7 cells 2 7 nM in KB-31 cells and 9 5 nM in CCRF-CEM cells Based on these pharmacological properties Epothilone D holds research potential in oncology and the study of drug resistance in cancer
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MW 507.7 Da, Purity >98%. Microtubule-stabilizing agent. Analog of Epothilone A and D (ab143615 and ab143616). Displays highest efficacy in class III β-tubulin overexpressing malignancies. Inhibits Paclitaxel (ab120143)-resistant cell lines. Shows antitumor effects in vivo. Orally active.
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Zearalenone is a resorcylic acid lactone mycotoxin produced by Fusarium species, supplied as an analytical standard for research into estrogenic activity and mycotoxin contamination. The material is provided as a measured solid and is accompanied by supporting documentation for research and analytical use.
High purity (98.85%) suitable for analytical applications.
Molecular formula C18H22O5 and molecular weight 318.36.
Provided as a 50 mg solid; other pack sizes and a 10 mM DMSO solution are available.
Includes certificate of analysis and safety data sheet for traceability.
Intended for research and analytical testing of mycotoxin contamination and estrogenic effects.
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