Phenylpropanoids and polyketides
Medchemexpress LLC Trans-chalcone | 614-47-1 | MFCD00003082 | 98.8% | 208.26 g/mol | C15H12O | 500g
trans-Chalcone isolated from Aronia melanocarpa skin is a biphenolic core structure of flavonoids precursor trans-Chalcone is a potent fatty acid synthase (FAS) and -amylase inhibitor trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7 trans-Chalcone has antifungal and anticancer activity[1][2][3]
Medchemexpress LLC 5,7-dimethoxyflavone | 21392-57-4 | MFCD00016943 | 282.29 g/mol | C17H14O4 | 10 MG
5,7-Dimethoxyflavone is a flavone derivative supplied as an analytical standard for research and analytical applications. It occurs naturally in Kaempferia parviflora and is used in studies of metabolic enzyme interactions, transporter inhibition, and biological activity profiling.
- Analytical standard suitable for assay and quantification.
- Natural flavone component used in phytochemical research.
- Documented inhibitor activity against cytochrome P450 enzymes and BCRP, useful in metabolism and transporter studies.
- Supplied in small mass quantities appropriate for analytical work.
- Molecular formula C17H14O4 and molecular weight 282.29 g/mol.
Medchemexpress LLC Cinnamyl-3,4-dihydroxy-α-cyanocinnamate | 132465-11-3 | 99.4% | 321.33 | 100 MG
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) is a potent inhibitor of 12/15-Lipoxygenases (LO) and has potential for research related to type 1 diabetes mellitus. The compound's efficacy in suppressing transendothelial dextran transport, particularly when increased by high glucose or 12(S)-HETE, has been observed in vitro. It has also been shown to mitigate the destruction of the endothelial cell barrier by antagonizing the effect of high glucose on protein phosphorylation, a finding further supported by mouse diabetes mellitus models.
- Potent 12/15-Lipoxygenases (LO) inhibitor
- Potential for research of type 1 diabetes mellitus
- Partially suppresses transendothelial dextran transport
- Mitigates destruction of the endothelial cell barrier
- Antagonizes effect of high glucose on protein phosphorylation
Medchemexpress LLC Catechin (Standard) | 154-23-4 | 290.27 | 100 MG
Catechin (Standard) is the analytical standard of Catechin, intended for research and analytical applications. It inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
- Used as an analytical reference standard.
- Commonly used in qualitative research experiments.
- Commonly used in quantitative research experiments.
- Commonly used in methodological research experiments.
- Suitable for HPLC.
- Suitable for GC.
- Suitable for MS.
eMolecules 332-04-7 | 4-(4-Fluorobenzyloxy)chlorobenzene | Oakwood Chemical | MFCD05105278 | 236.670 | C13H10ClFO | 98.000 | Fc1ccc(COc2ccc(Cl)cc2)cc1 | 1g | 537680719
4-(4-Fluorobenzyloxy)chlorobenzene | Oakwood Chemical | 332-04-7 | MFCD05105278 | 236.670 | C13H10ClFO | 98.000 | Fc1ccc(COc2ccc(Cl)cc2)cc1 | 1g | 537680719
Medchemexpress LLC Catechin | 154-23-4 | 290.27 | 10 MM 1 ML
Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. It exhibits potent inhibitory activity against COX-1 and can induce apoptosis in certain cancer cells. Catechin has also shown a dose-dependent reduction in cell viability and an increase in apoptosis markers in vitro. In animal studies, it has demonstrated the ability to prevent episodic memory deficits.
- Inhibits cyclooxygenase-1.
- Reduces cell viability in a dose-dependent manner.
- Increases the induction of apoptosis.
- Prevents time-induced episodic memory deficits.
eMolecules 2187435-45-4 | (4-(Ethylamino)-6-fluoropyridin-3-yl)methanol | Apollo Scientific | MFCD31536741 | 170.187 | C8H11FN2O | 95.000 | CCNc1cc(F)ncc1CO | 250mg | 562446440
(4-(Ethylamino)-6-fluoropyridin-3-yl)methanol | Apollo Scientific | 2187435-45-4 | MFCD31536741 | 170.187 | C8H11FN2O | 95.000 | CCNc1cc(F)ncc1CO | 250mg | 562446440
Medchemexpress LLC Gallocatechin gallate | 5127-64-0 | 5 MG
Gallocatechin gallate is a flavonoid product isolated from the herbs of Celastrus orbiculatus. This chemical compound is provided as a solid, typically white to off-white in appearance, with a purity of 98%.
- Molecular weight: 458.37
- Chemical formula: C22H18O11
- Recommended storage at -20°C, sealed, away from moisture and light
- In solvent storage at -80°C for 6 months or -20°C for 1 month
- For research use only
Medchemexpress LLC 6-Methoxyflavone 100mg
6-Methoxyflavone is an orally active methoxyflavone 6-Methoxyflavone suppresses neuroinflammation in microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF- B dependent pathways and the activation of HO-1/NQO-1 signaling 6-Methoxyflavone induces S-phase arrest through the CCNA2/CDK2/p21CIP1 signaling pathway and activates the PERK/EIF2a/ATF4/CHOP pathway in HeLa cells 6-Methoxyflavone acts as a Flumazenil (HY-B0009)-insensitive positive allosteric modulator at human recombinant 1 2 2L and 2 2 2L GABA receptors 6-Methoxyflavone inhibits NFAT Translocation into the nucleus and suppresses T cell activation 6-Methoxyflavone partially restores chronic ethanol-induced behavioral deficits in mice 6-Methoxyflavone antagonizes chronic constriction injury and diabetes associated neuropathic nociception expression 6-Methoxyflavone can be used for the study of cancer inflammation and neurological diseases[1][2][3][4][5][6][7][8]
TARGETMOL CHEMICALS INC PUERARIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Puerarin (Kakonein) also known as Kakonein is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist. purity: 99%