Diterpenoids
Medchemexpress LLC Phytol (Standard) | 150-86-7 | 250 MG
Phytol (Standard) is a highly pure analytical standard, identified by CAS number 150-86-7, specifically developed for research and analytical applications. This orally active diterpenoid alcohol is naturally extracted from chlorophyll and presented as a yellow liquid. It is known for its diverse biological activities, including antioxidant, anti-inflammatory, anti-schistosomiasis, and antibacterial properties.
- Analytical standard for research and analytical applications
- Extracted from chlorophyll
- Orally active diterpenoid alcohol
- Exhibits antioxidant activity
- Exhibits anti-inflammatory activity
- Exhibits anti-schistosomiasis activity
- Exhibits antibacterial activity
- Purity of 99.87% (HPLC)
- Supplied as a yellow liquid
Medchemexpress LLC Phytol (Standard) | 150-86-7 | 100 MG
Phytol (Standard) is an analytical standard of Phytol, derived from chlorophyll, and is suitable for research and analytical applications. This orally active diterpenoid alcohol exhibits antioxidant, anti-inflammatory, anti-schistosomiasis, and antibacterial properties.
- Analytical standard for qualitative, quantitative, and methodological research
- Used in HPLC, GC, and MS experiments
- Possesses antioxidant, anti-inflammatory, anti-schistosomiasis, and antibacterial activities
TARGETMOL CHEMICALS INC Cryptotanshinone 50MG
Also available in 1 mL, 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. Cryptotanshinone (Cryptotanshinon), a STAT3 inhibitor (IC50 4.6 uM) in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a little effect on STAT3 Ser727, but no inhibition for STAT1 nor STAT5. Purity 98.1%
Medchemexpress LLC Tanshinone IIA anhydride | 61077-78-9 | 310.34 | 1 MG
Tanshinone IIA anhydride is a potent and irreversible human carboxylesterase (CE) inhibitor. It has Ki values of 1.9 nM for human CE1 and 1.4 nM for human intestinal CE (hiCE).
- Potent and irreversible human carboxylesterase (CE) inhibitor
- Ki values of 1.9 nM for human CE1
- Ki values of 1.4 nM for human intestinal CE (hiCE)
Medchemexpress LLC Tanshinone IIA sulfonate sodium | 69659-80-9 | 396.39 | 500 MG
Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA. This compound acts as an inhibitor of store-operated Ca2+ entry (SOCE) and is primarily used in the treatment of cardiovascular disorders. It is intended for research purposes only.
- Inhibits hypoxia-induced PKG and PPAR-γ downregulation in PASMCs.
- Suppresses TRPC1 and TRPC6 expression.
- Inhibits basal calcium concentration and SOCE.
- Primarily inhibits CYP3A4 activities in vitro.
- Shows protective effects against Aβ-induced cell toxicity in SH-SY5Y cells.
- Alleviates hypoxia-induced characteristic changes in chronic hypoxia PH rat models.
- Effectively prevents peritoneal adhesion in rats.
Medchemexpress LLC Cucurbitacin IIa | 58546-34-2 | 562.73 | 1 MG
Cucurbitacin IIa, also known as Hemslecin A, is an orally active EGFR inhibitor capable of permeating the blood-brain barrier. It demonstrates an IC50 of 1.455 nM against human EGFR and exhibits anti-inflammatory activity by inhibiting the EGFR-MAPK signaling pathway.
Features and Benefits:
- Induces caspase-3-dependent apoptosis.
- Downregulates survivin expression.
- Enhances autophagy levels.
- Disrupts the actin cytoskeleton via actin aggregation.
- Arrests the cell cycle at the G2/M phase.
- Supports research into inflammation-related diseases.
- Useful in studies on depression and cancers like non-small cell lung cancer.
Medchemexpress LLC TANSHINONE IIA, 50 MG
MedChemExpress LLC| Tanshinone IIA | 50 mg | HY-N0135 | Purity 99.74% | 568-72-9 | MW: 294.34
Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 97.0% | 278.32 g/mol | C14H14O4S | 5 MG
This bisphenol-derived small-molecule inhibits DNA topoisomerase II alpha and is intended for research use. It demonstrates topo II inhibitory activity and in vitro cell growth inhibition, making it suitable for biochemical and anticancer studies.
- Small-molecule inhibitor of DNA topoisomerase II alpha.
- Bisphenol-derived structure; formula C14H14O4S.
- Documented in vitro topo II inhibitory activity and cell growth IC50 values.
- Supplied in small quantities for research use (5 mg pack).
- Intended for biochemical and anticancer research applications.
Selleck Chemical LLC Tanshinone IIA 50mg 568-72-9 Tanshinone B
Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
eMolecules Tanshinone IIA | 568-72-9 | MFCD00238692 | 100mg
Ambeed | Tanshinone IIA | 100mg | 552521161 | A104838 | | 568-72-9 | MFCD00238692 | 294.350 | C19H18O3
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Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 97.0% | 278.32 g·mol-1 | C14H14O4S | 25 MG
Topoisomerase IIα-IN-9 is a bisphenol-derived small-molecule inhibitor of human DNA topoisomerase IIα intended for research use. Reported biochemical activity includes Topo II inhibition (IC50 ≈ 571 μM) and cell growth inhibitory activity in K562 and CHO cells (IC50 ≈ 117 μM and 218 μM, respectively). Molecular formula C14H14O4S and molecular weight 278.32 g·mol-1 are provided; consult the Certificate of Analysis for purity and storage conditions.
- Moderate inhibitor of DNA topoisomerase IIα.
- Exhibits cell growth inhibition in selected cell lines.
- Provided as a characterized small molecule with formula and molecular weight.
- Suitable for biochemical assays and cell-based research applications.
- Certificate of Analysis available for purity and handling details.
Apexbio Technology LLC Tanshinone IIA 568-72-9 10mM (in 1mL DMSO)
Tanshinone IIA (CAS 568-72-9) is a diterpene quinone extracted from the medicinal plant Salvia miltiorrhiza (Danshen) It modulates cellular signaling by inhibiting the binding of transcription factors NF- B and AP-1 to DNA thereby regulating gene expression associated with inflammation and proliferation Tanshinone IIA has demonstrated the capacity to suppress -amyloid aggregation and protect neuronal PC12 cells against -amyloid-induced apoptosis It exhibits both antioxidant and anti-inflammatory properties supporting its use in studies related to oncology neurodegeneration and inflammation
Apexbio Technology LLC Tanshinone IIA 568-72-9 20mg
Tanshinone IIA (CAS 568-72-9) is a diterpene quinone extracted from the medicinal plant Salvia miltiorrhiza (Danshen) It modulates cellular signaling by inhibiting the binding of transcription factors NF- B and AP-1 to DNA thereby regulating gene expression associated with inflammation and proliferation Tanshinone IIA has demonstrated the capacity to suppress -amyloid aggregation and protect neuronal PC12 cells against -amyloid-induced apoptosis It exhibits both antioxidant and anti-inflammatory properties supporting its use in studies related to oncology neurodegeneration and inflammation