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Filtered Search Results
Medchemexpress LLC 2-(2-chlorophenyl)-2-(5,7-dichloro-3-(hydroxymethyl)-4,6-dimethyl-1H-indol-2-yl)-N-((4-methylphenyl)su | 2244452-09-1 | 99.6% | 499.36 g/mol | C21H20Cl2N2O6S | 1MG
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BI-4924 is a potent, selective small-molecule inhibitor of phosphoglycerate dehydrogenase (PHGDH) used in biochemical and cellular research to probe serine biosynthesis and PHGDH-dependent metabolism. The compound is a hydroxymethylene-bearing carboxylic acid derivative (CAS 2244452-09-1) with characterized physicochemical and solubility properties.
- Potent PHGDH inhibition: IC50 = 3 nM.
- Disrupts serine biosynthesis in cells (IC50 ≈ 2.2 μM at 72 h).
- Chemical formula C21H20Cl2N2O6S; molecular weight 499.36 g/mol.
- High purity: 99.6% (reported by supplier).
- Form: powder; suitable for DMSO stock solutions.
- Solubility in vitro: DMSO 125 mg/mL (≈250 mM; ultrasonic recommended).
- In vivo formulations documented for multiple vehicles at ≥2.08 mg/mL.
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![eMolecules 2135683-42-8 | [(3S)-1-tert-butoxycarbonylpyrrolidin-3-yl]methylzinc iodide, 0.5M in THF | Synthonix - Stock376.540 | C10H18INO2Zn | 0.000 | [I-].CC(C)(C)OC(=O)N1CC[C@H](C[Zn+])C1 | 50ml | 353003199](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697882.jpg-250.jpg)
eMolecules 2135683-42-8 | [(3S)-1-tert-butoxycarbonylpyrrolidin-3-yl]methylzinc iodide, 0.5M in THF | Synthonix - Stock376.540 | C10H18INO2Zn | 0.000 | [I-].CC(C)(C)OC(=O)N1CC[C@H](C[Zn+])C1 | 50ml | 353003199
[(3S)-1-tert-butoxycarbonylpyrrolidin-3-yl]methylzinc iodide, 0.5M in THF | Synthonix - Stock | 2135683-42-8376.540 | C10H18INO2Zn | 0.000 | [I-].CC(C)(C)OC(=O)N1CC[C@H](C[Zn+])C1 | 50ml | 353003199
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![eMolecules 328000-16-4 | 2-(Benzyloxy)phenylmagnesium bromide, 0.50 M in THF | Synthonix | MFCD08705262 | 287.439 | C13H11BrMgO | 0.000 | [Br-].[Mg+]c1ccccc1OCc1ccccc1 | 100ml | 702445862](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695035.jpg-250.jpg)
eMolecules 328000-16-4 | 2-(Benzyloxy)phenylmagnesium bromide, 0.50 M in THF | Synthonix | MFCD08705262 | 287.439 | C13H11BrMgO | 0.000 | [Br-].[Mg+]c1ccccc1OCc1ccccc1 | 100ml | 702445862
2-(Benzyloxy)phenylmagnesium bromide, 0.50 M in THF | Synthonix | 328000-16-4 | MFCD08705262 | 287.439 | C13H11BrMgO | 0.000 | [Br-].[Mg+]c1ccccc1OCc1ccccc1 | 100ml | 702445862
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![eMolecules 63746-81-6 | 5-Bromo-2-thienylmagnesium bromide, 0.50 M in THF | Synthonix | MFCD22684738 | 266.230 | C4H2Br2MgS | 0.000 | [Br-].[Mg+]c1ccc(Br)s1 | 100ml | 702445858](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695039.jpg-250.jpg)
eMolecules 63746-81-6 | 5-Bromo-2-thienylmagnesium bromide, 0.50 M in THF | Synthonix | MFCD22684738 | 266.230 | C4H2Br2MgS | 0.000 | [Br-].[Mg+]c1ccc(Br)s1 | 100ml | 702445858
5-Bromo-2-thienylmagnesium bromide, 0.50 M in THF | Synthonix | 63746-81-6 | MFCD22684738 | 266.230 | C4H2Br2MgS | 0.000 | [Br-].[Mg+]c1ccc(Br)s1 | 100ml | 702445858
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![eMolecules 1610475-27-8 | 4-Chloro-2,6-dimethylphenylmagnesium bromide, 0.50 M in THF | Synthonix243.810 | C8H8BrClMg | 95.000 | [Br-].Cc1cc(Cl)cc(C)c1[Mg+] | 100ml | 649431011](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695143.jpg-250.jpg)
eMolecules 1610475-27-8 | 4-Chloro-2,6-dimethylphenylmagnesium bromide, 0.50 M in THF | Synthonix243.810 | C8H8BrClMg | 95.000 | [Br-].Cc1cc(Cl)cc(C)c1[Mg+] | 100ml | 649431011
4-Chloro-2,6-dimethylphenylmagnesium bromide, 0.50 M in THF | Synthonix | 1610475-27-8243.810 | C8H8BrClMg | 95.000 | [Br-].Cc1cc(Cl)cc(C)c1[Mg+] | 100ml | 649431011
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![eMolecules 2186693-92-3 | 2-chloropyridin-4-ylzinc iodide, 0.50 M in THF | Synthonix304.820 | C5H3ClINZn | 0.000 | [I-].Clc1cc([Zn+])ccn1 | 100ml | 532652673](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696310.jpg-250.jpg)
eMolecules 2186693-92-3 | 2-chloropyridin-4-ylzinc iodide, 0.50 M in THF | Synthonix304.820 | C5H3ClINZn | 0.000 | [I-].Clc1cc([Zn+])ccn1 | 100ml | 532652673
2-chloropyridin-4-ylzinc iodide, 0.50 M in THF | Synthonix | 2186693-92-3304.820 | C5H3ClINZn | 0.000 | [I-].Clc1cc([Zn+])ccn1 | 100ml | 532652673
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![eMolecules 89980-69-8 | 3,4-Dimethoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD01311476 | 241.367 | C8H9BrMgO2 | 0.000 | [Br-].COc1ccc([Mg+])cc1OC | 100ml | 437237133](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697676.jpg-250.jpg)
eMolecules 89980-69-8 | 3,4-Dimethoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD01311476 | 241.367 | C8H9BrMgO2 | 0.000 | [Br-].COc1ccc([Mg+])cc1OC | 100ml | 437237133
3,4-Dimethoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 89980-69-8 | MFCD01311476 | 241.367 | C8H9BrMgO2 | 0.000 | [Br-].COc1ccc([Mg+])cc1OC | 100ml | 437237133
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![eMolecules 352525-65-6 | (4-bromo-3-fluorophenyl)zinc iodide, 0.50 M in THF | Synthonix366.280 | C6H3BrFIZn | 0.000 | [I-].Fc1cc([Zn+])ccc1Br | 100ml | 532652603](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696368.jpg-250.jpg)
eMolecules 352525-65-6 | (4-bromo-3-fluorophenyl)zinc iodide, 0.50 M in THF | Synthonix366.280 | C6H3BrFIZn | 0.000 | [I-].Fc1cc([Zn+])ccc1Br | 100ml | 532652603
(4-bromo-3-fluorophenyl)zinc iodide, 0.50 M in THF | Synthonix | 352525-65-6366.280 | C6H3BrFIZn | 0.000 | [I-].Fc1cc([Zn+])ccc1Br | 100ml | 532652603
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Medchemexpress LLC Cevimeline hydrochloride (synonyms: AF102B hydrochloride) | 107220-28-0 | 98.7% | C10H18ClNOS | 1 ML
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Cevimeline hydrochloride is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist. It stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia. It can also cross the blood-brain barrier.
- Quinuclidine derivative of acetylcholine
- Selective and orally active muscarinic M1 and M3 receptor agonist
- Stimulates secretion by salivary glands
- Used as a sialogogue for xerostomia
- Can cross the blood-brain barrier
- For research use only
- Molecular weight: 235.77
- Appearance: white to off-white solid
- Soluble in H2O at concentrations ≥ 50 mg/mL
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![eMolecules 737797-48-7 | 4-tert-Butylbenzylzinc bromide, 0.50 M in THF | Synthonix292.530 | C11H15BrZn | 0.000 | [Br-].CC(C)(C)c1ccc(C[Zn+])cc1 | 25ml | 627353508](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695433.jpg-250.jpg)
eMolecules 737797-48-7 | 4-tert-Butylbenzylzinc bromide, 0.50 M in THF | Synthonix292.530 | C11H15BrZn | 0.000 | [Br-].CC(C)(C)c1ccc(C[Zn+])cc1 | 25ml | 627353508
4-tert-Butylbenzylzinc bromide, 0.50 M in THF | Synthonix | 737797-48-7292.530 | C11H15BrZn | 0.000 | [Br-].CC(C)(C)c1ccc(C[Zn+])cc1 | 25ml | 627353508
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Medchemexpress LLC BI-847325 | 1207293-36-4 | 98.2% | 464.56 | 25 MG
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BI-847325 | 1207293-36-4 | 98.2% | 464.56 | 25 MG
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![eMolecules 26905-40-8 | 3-Methoxybenzylmagnesium chloride, 0.25 M in 2-MeTHF | Synthonix | MFCD01319896 | 180.910 | C8H9ClMgO | 0.000 | [Cl-].COc1cccc(C[Mg+])c1 | 25ml | 627353681](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695296.jpg-250.jpg)
eMolecules 26905-40-8 | 3-Methoxybenzylmagnesium chloride, 0.25 M in 2-MeTHF | Synthonix | MFCD01319896 | 180.910 | C8H9ClMgO | 0.000 | [Cl-].COc1cccc(C[Mg+])c1 | 25ml | 627353681
3-Methoxybenzylmagnesium chloride, 0.25 M in 2-MeTHF | Synthonix | 26905-40-8 | MFCD01319896 | 180.910 | C8H9ClMgO | 0.000 | [Cl-].COc1cccc(C[Mg+])c1 | 25ml | 627353681
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![eMolecules 78078-50-9 | [2-(1,3-dioxan-2-yl)ethyl]magnesium bromide, 0.5M in THF | Synthonix - Stock | MFCD00061518 | 219.361 | C6H11BrMgO2 | 0.000 | [Br-].[Mg+]CCC1OCCCO1 | 100ml | 437237092](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697717.jpg-250.jpg)
eMolecules 78078-50-9 | [2-(1,3-dioxan-2-yl)ethyl]magnesium bromide, 0.5M in THF | Synthonix - Stock | MFCD00061518 | 219.361 | C6H11BrMgO2 | 0.000 | [Br-].[Mg+]CCC1OCCCO1 | 100ml | 437237092
[2-(1,3-dioxan-2-yl)ethyl]magnesium bromide, 0.5M in THF | Synthonix - Stock | 78078-50-9 | MFCD00061518 | 219.361 | C6H11BrMgO2 | 0.000 | [Br-].[Mg+]CCC1OCCCO1 | 100ml | 437237092
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![eMolecules 126403-67-6 | Isobutylzinc bromide, 0.50 M in THF | Synthonix202.400 | C4H9BrZn | 0.000 | [Br-].CC(C)C[Zn+] | 100ml | 627353815](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695208.jpg-250.jpg)
eMolecules 126403-67-6 | Isobutylzinc bromide, 0.50 M in THF | Synthonix202.400 | C4H9BrZn | 0.000 | [Br-].CC(C)C[Zn+] | 100ml | 627353815
Isobutylzinc bromide, 0.50 M in THF | Synthonix | 126403-67-6202.400 | C4H9BrZn | 0.000 | [Br-].CC(C)C[Zn+] | 100ml | 627353815
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![eMolecules 352525-66-7 | 3-Chloro-4-methylphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01311461 | 317.860 | C7H6ClIZn | 0.000 | [I-].Cc1ccc([Zn+])cc1Cl | 50ml | 532652686](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696297.jpg-250.jpg)
eMolecules 352525-66-7 | 3-Chloro-4-methylphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01311461 | 317.860 | C7H6ClIZn | 0.000 | [I-].Cc1ccc([Zn+])cc1Cl | 50ml | 532652686
3-Chloro-4-methylphenylzinc iodide, 0.50 M in THF | Synthonix | 352525-66-7 | MFCD01311461 | 317.860 | C7H6ClIZn | 0.000 | [I-].Cc1ccc([Zn+])cc1Cl | 50ml | 532652686
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