Naphthalenes
- (2)
- (1)
- (185)
- (9)
- (1)
- (28)
- (1)
- (9)
- (103)
- (3)
- (35)
- (6)
- (2)
- (1)
- (1)
- (2)
- (5)
- (1)
- (1)
- (1)
- (7)
- (241)
- (2)
- (10)
- (31)
- (24)
- (2)
- (1)
- (1)
- (202)
- (1)
- (1)
- (1)
- (17)
- (1)
- (11)
- (81)
- (1)
- (10)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (17)
- (3)
- (13)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (5)
- (6)
- (9)
- (2)
- (8)
- (6)
- (28)
- (27)
- (1)
- (1)
- (10)
- (7)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (11)
- (24)
- (8)
- (6)
- (2)
- (5)
- (9)
- (2)
- (1)
- (2)
- (1)
- (1)
- (9)
- (2)
- (1)
- (1)
- (5)
- (3)
- (1)
- (1)
- (1)
- (1)
- (16)
- (5)
- (7)
- (3)
- (2)
- (2)
- (13)
- (15)
- (2)
- (6)
- (1)
- (2)
- (2)
- (2)
- (4)
- (1)
- (2)
- (1)
- (6)
- (2)
- (1)
- (1)
- (1)
- (8)
- (3)
- (4)
- (2)
- (10)
- (6)
- (3)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (7)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (8)
- (3)
- (1)
- (8)
- (2)
- (1)
- (2)
- (9)
- (2)
- (9)
- (12)
- (1)
- (1)
- (14)
- (13)
- (1)
- (1)
- (1)
- (1)
- (5)
- (2)
- (1)
- (8)
- (8)
- (6)
- (2)
- (2)
- (4)
- (1)
- (3)
- (1)
- (1)
- (13)
- (7)
- (1)
- (1)
- (1)
- (2)
- (1)
- (10)
- (2)
- (4)
- (9)
- (1)
- (1)
- (3)
- (3)
- (1)
- (4)
- (1)
- (13)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (4)
- (1)
- (1)
- (1)
- (4)
- (3)
- (2)
- (3)
- (4)
- (3)
- (1)
- (2)
- (3)
- (2)
- (2)
- (6)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (4)
- (4)
- (2)
- (1)
- (2)
- (7)
- (2)
- (20)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (9)
- (2)
- (1)
- (2)
- (3)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (5)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (1)
- (4)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (4)
- (1)
- (4)
- (2)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (2)
- (2)
- (1)
- (2)
- (4)
- (1)
- (1)
- (8)
- (3)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (14)
- (1)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (5)
- (2)
- (3)
- (5)
- (1)
- (1)
- (2)
- (4)
- (8)
- (2)
- (2)
- (1)
- (1)
- (1)
- (4)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (4)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (3)
- (7)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (2)
- (3)
- (1)
- (2)
- (1)
- (3)
- (2)
- (7)
- (2)
- (2)
- (8)
- (2)
- (1)
- (9)
- (2)
- (4)
- (3)
- (1)
- (2)
- (12)
- (1)
- (11)
- (14)
- (2)
- (1)
- (1)
- (15)
- (9)
- (7)
- (28)
- (2)
- (61)
- (58)
- (30)
- (1)
- (13)
- (54)
- (2)
- (1)
- (36)
- (2)
- (2)
- (1)
- (2)
- (4)
- (2)
- (15)
- (1)
- (1)
- (3)
- (1)
- (2)
- (10)
- (1)
- (3)
- (3)
- (3)
- (9)
- (11)
- (2)
- (3)
- (3)
- (29)
- (6)
- (94)
- (127)
- (3)
- (74)
- (12)
- (3)
- (3)
- (4)
- (440)
- (2)
- (8)
- (5)
- (1)
- (3)
- (4)
- (5)
- (6)
- (1)
- (1)
- (2)
- (28)
- (3)
- (6)
- (1)
- (97)
- (1)
- (1)
- (2)
- (2)
- (12)
- (5)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (5)
- (1)
- (2)
- (1)
- (2)
- (7)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (4)
- (4)
- (3)
- (5)
- (3)
- (1)
- (3)
- (6)
- (3)
- (3)
- (5)
- (8)
- (2)
- (4)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
Filtered Search Results
Medchemexpress LLC BI-4020 | 2664214-60-0 | 99.3% | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. It inhibits the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the double mutant EGFR del19 T790M, and primary mutant EGFR del19 (IC50=1 nM). It also shows activity against EGFR wt (IC50=190 nM). This product demonstrates high kinome selectivity and good DMPK properties and is for research use only.
- Fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor
- Inhibits triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM)
- Inhibits double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM)
- Shows activity against EGFR wt (IC50=190 nM)
- Demonstrates high kinome selectivity and good DMPK properties
- Leads to tumor regressions in human PC-9 triple mutant NSCLC xenograft model in mice
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Ambeed 1 6Dihydroxynaphthalene
1,6-Dihydroxynaphthalene, 575-44-0, 97%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 50525-27-4 | Ambeed | Tris(22-bipyridyl)ruthenium(II) chloride hexahydrate | 1g | 490493309 | A109916 | MFCD26940142 | 748.62 | C30H36Cl2N6O6Ru
Ambeed | Tris(22-bipyridyl)ruthenium(II) chloride hexahydrate | 1g | 490493309 | A109916 | 50525-27-4 | MFCD26940142 | 748.620 | C30H36Cl2N6O6Ru
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000290941 SR-BI/SCARB1 MOUSE 100UG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Chemscene CHEMSCENE
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000576283 6-BROMO-2-NAPHTHOL 500G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Ambeed AMBEED
5000847808 2 5-DICHLORO-1 8-NAPHTH 250MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Amiodarone hydrochloride (Standard) | 19774-82-4 | C25H30CII2NO3 | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Amiodarone hydrochloride (Standard) is an analytical standard intended for research and analytical applications. This benzofuran-based Class III antiarrhythmic agent inhibits WT outward IhERG tails with an IC50 of approximately 45 nM. It also induces cell proliferation and myofibroblast differentiation through ERK1/2 and p38 MAPK signaling in fibroblasts. Amiodarone hydrochloride is utilized in the research of both supraventricular and ventricular arrhythmias. Please store the product under the recommended conditions found in the Certificate of Analysis.
- Analytical standard
- Intended for research and analytical applications
- Benzofuran-based Class III antiarrhythmic agent
- Inhibits WT outward IhERG tails
- Induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts
- Used in research of supraventricular and ventricular arrhythmias
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000570322 BI-2865-5MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Tetrahydrofolic acid | 135-16-0 | C19H23N7O6 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Tetrahydrofolic acid is the biologically active vitamin B9 folate derivative. It acts as a donor of one-carbon groups for amino acids, nucleic acids, and lipids, and serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid.
- Functions as an endogenous metabolite
- Induces cytotoxicity in Adh5- and Fanconi anemia (FA)-deficient cells
- Promotes FANCD2 and ser139-H2AX focus formation in Adh5-/- cells
- Activates the DNA damage response
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC BI 2536(Synonyms: BI-2536, BI2536, Plk1 inhibitor BI 2536), 10mg, CAS: 755038-02-9.
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
BI 2536 (CAS number 755038-02-9) is an ATP-competitive inhibitor selectively targeting human polo-like kinase 1 (PLK1) exhibiting an IC50 value of approximately 0 83 nM Comparatively BI 2536 shows substantially less affinity towards other kinases In vitro studies demonstrate that BI 2536 inhibits proliferation of various human tumor cell lines (EC50 values ranging from 2 to 25 nM) and induces G2/M cell cycle arrest accompanied by apoptosis as evidenced in HeLa cervical cancer cells In vivo data from xenograft tumor models indicate that BI 2536 administered intravenously on a weekly or biweekly schedule possesses antitumor efficacy
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Chemscene CHEMSCENE
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000578289 4-FLUORO-1-NAPHTHALDEHYD 250MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Ambeed AMBEED
5000847763 3- 4-BROMOPHENYL -1-PHE 250MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
c1cccc2ccccc12 | 100g | 379190899](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000491765.jpg-250.jpg)
eMolecules 3886-70-2 | (1R)-1-(naphthalen-1-yl)ethan-1-amine | Pharmablock - Stock | MFCD00064114 | 171.243 | C12H13N | 97.000 | C[C@@H](N)c1cccc2ccccc12 | 100g | 379190899
(1R)-1-(naphthalen-1-yl)ethan-1-amine | Pharmablock - Stock | 3886-70-2 | MFCD00064114 | 171.243 | C12H13N | 97.000 | C[C@@H](N)c1cccc2ccccc12 | 100g | 379190899
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Chemscene CHEMSCENE
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000575822 6-BROMO-2-NAPHTHOL 100G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Mocravimod hydrochloride | 509088-69-1 | 99.99% | 480.45 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Mocravimod hydrochloride is an orally active sphingosine-1-phosphate receptor (S1PR) modulator. It works by blocking the signal required by T cells to egress from lymph nodes and other lymphoid organs, preferentially binding to S1PR1 over S1PR2 and S1PR3 in cardiomyocytes. This compound retains T cell effector function and is suitable for various research applications.
- Significantly lowers the concentration of reactive oxygen species (ROS).
- Prevents mitochondrial permeability transition pore opening.
- Boosts mitochondrial membrane potential (MMP).
- Increases phosphorylation of AKT, EKR, GSK-3β, JAK2, and STAT3.
- Retains T cell effector function.
- Used for the study of acute myelogenous leukemia, diabetes, and Myocardial Ischemia-Reperfusion Injury (MIRI).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More