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Filtered Search Results
eMolecules 91469-55-5 | 1-AMINO-3-CYCLOPENTENE HCL | AstaTech | MFCD01630740 | 119.590 | C5H10ClN | 98.000 | Cl.NC1CC=CC1 | 5g | 112529258
1-AMINO-3-CYCLOPENTENE HCL | AstaTech | 91469-55-5 | MFCD01630740 | 119.590 | C5H10ClN | 98.000 | Cl.NC1CC=CC1 | 5g | 112529258
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Medchemexpress LLC VE-821 | 1232410-49-9 | 99.7% | 368.41 | 50 MG
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VE-821 is a potent ATP-competitive inhibitor of ATR, with Ki/IC50 values of 13 nM/26 nM. It demonstrates excellent selectivity for ATR, showing minimal cross-reactivity against related PIKKs such as ATM, DNA-PK, mTOR, and PI3Kγ.
- Shows minimal cross-reactivity against related PIKKs ATM, DNA-PK, mTOR, and PI3Kγ
- Significantly enhances the sensitivity of PSN-1, MiaPaCa-2, and primary PancM pancreatic cancer cells to radiation and Gemcitabine
- ATR inhibition by VE-821 leads to inhibition of radiation-induced G2/M arrest in cancer cells
- Inhibits phosphorylation of Chk1 (Ser 345) in PSN-1 and MiaPaCa-2 cells after treatment with Gemcitabine, radiation, or both
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Medchemexpress LLC Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate | 1049004-32-1 | 280.17 | 5 G
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Bpin-Cyclohexene-COOEt, also known as Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate, is a PROTAC linker belonging to the PEG class. It is designed for use in the synthesis of PROTAC molecules. This compound is a colorless to light yellow liquid.
- Intended for research use only.
- Unstable in solutions, requiring freshly prepared solutions for optimal use.
- Molecular weight of 280.17.
- Purity of 97.0%.
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Medchemexpress LLC 5-phenyl-1-pentyne | 1823-14-9 | MFCD00039813 | 98.0% | 144.21 g/mol | C11H12 | 250 MG
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5-Phenyl-1-pentyne is an aromatic alkyne used as an intermediate in organic synthesis and is reported to have antibacterial and antitumor activity. It is commonly used to assemble more complex molecules and to support medicinal chemistry research and structure-activity relationship studies.
- High purity suitable for research applications.
- Available in multiple pack sizes for lab use.
- Used as a reaction intermediate in synthetic chemistry.
- Supportive for medicinal chemistry and SAR studies.
- Identified by CAS and molecular data for clear substance identification.
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Medchemexpress LLC Ethyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enyl)acetate | 1166829-70-4 | >97.0% | 294.19 | C16H27BO4 | 500 MG
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Bpin-Cyclohexene-C-COOEt is a boron-pinacol substituted cyclohexene ethyl acetate used as a PROTAC linker in medicinal chemistry and targeted protein degradation research. The compound is supplied for research use only and is reported to have high purity and defined molecular characteristics.
- used as a PROtac linker in targeted protein degradation research.
- molecular formula: C16H27BO4.
- molecular weight: 294.19 g/mol.
- high purity (>97.0%).
- suitable for synthesis of SMARCA2/4 degrader scaffolds and related intermediates.
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Medchemexpress LLC Bay 65-1942 hydrochloride | 600734-06-3 | 99.4% | C22H26ClN3O4 | 25 MG
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Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor, appearing as a white to off-white solid. It has demonstrated efficacy in reducing left ventricular infarct size and attenuating CK-MB levels in vitro. In vivo studies show synergistic inhibition of cell viability when combined with AZD6244, and it induces caspase 3/7 activation, making it a valuable tool for research in cancer, inflammation, and immune system diseases.
- ATP-competitive and selective IKKβ inhibitor
- White to off-white solid appearance
- Soluble in DMSO (50 mg/mL) and H2O (2.17 mg/mL)
- Inhibits IKKβ activity
- Decreases left ventricular infarct size in vitro
- Attenuates CK-MB levels in vitro
- Demonstrates synergistic inhibition of cell viability with AZD6244 in vivo
- Induces caspase 3/7 activation in vivo
- Relevant for research in cancer, inflammation, and immune system diseases
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Medchemexpress LLC Tau protein (592-597), human TFA | 2703746-44-3 | 95.17% | 868.94 | 5 MG
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Tau protein (592-597), human TFA is a peptide fragment of human Tau protein. The dysfunction of Tau protein is involved in neurodegeneration and dementia. It is a white to off-white solid with a molecular weight of 868.94 and a chemical formula of C36H63F3N10O11. This product is for research use only.
- Purity of 95.17%
- Sequence is Ac-Val-Gln-Ile-Ile-Asn-Lys-NH2 (Ac-VQIINK-NH2)
- Solubility of ≥ 2 mg/mL (2.30 mM) in H2O
- Recommended storage for powder at -80°C for 2 years or -20°C for 1 year
- Recommended storage for solutions at -80°C for 6 months or -20°C for 1 month (sealed, away from moisture)
- Associated with Neuronal Signaling, Tau Protein, neurological disease, and neurodegenerative disease
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eMolecules 7-Tetradecene | 10374-74-0 | MFCD00009550 | 1g
Oakwood Chemicals | 7-Tetradecene | 1g | 480151123 | 099796 | | 10374-74-0 | MFCD00009550 | 196.378 | C14H28
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Medchemexpress LLC 1-dodecene | 112-41-4 | MFCD00008961 | 96.9% | 168.32 g/mol | C12H24 | 100 G
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1-Dodecene is a linear alpha-olefin (C12H24) used as a reagent and chemical intermediate in organic synthesis and in the manufacture of surfactants and lubricants. It is supplied as a colorless to light yellow liquid with a GC-reported purity of 96.9% and a molecular weight of 168.32 g/mol.
- Linear alpha-olefin reagent for organic synthesis and intermediates.
- High GC purity (96.9%).
- Colorless to light yellow liquid, easy to handle in standard laboratory conditions.
- Molecular formula C12H24; molecular weight 168.32 g/mol.
- Suitable for use in surfactant and lubricant production.
- Certificate of analysis and safety data sheet available for quality and safety verification.
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Strem, An Ascensus Company Manganocene 98% 1g
CAS# 73138-26-8. 1g. Bis(cyclopentadienyl)manganese, 98+% (Manganocene). MFCD00045468. Molecular Weight: 185.13. Molecular Formula: (C5H5)2Mn. Color/form: brown xtl. Strem# 25-0200. http://www.strem.com/catalog/v/25-0200/
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Medchemexpress LLC Tau protein (592-597), human TFA | 2703746-44-3 | 95.17% | 868.94 | 10 MG
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Tau protein (592-597), human TFA is a peptide fragment of human Tau protein. The dysfunction of Tau protein is involved in neurodegeneration and dementia.
- Peptide fragment of human Tau protein.
- Target: Tau protein.
- Involved in neuronal signaling pathway.
- Appearance: White to off-white solid.
- Purity: 95.17%.
- Soluble in H2O: ≥ 2 mg/mL (2.30 mM).
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Cayman Chemical cis-10-Nonadecenoic Acid, Purity: ≥98%, CAS: 73033-09-7, 250 mg
A monounsaturated long chain fatty acid with potential antitumor and p53 inhibitory activity
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Medchemexpress LLC Cis/trans-nepetalactol | 109215-55-6 | 95.0% | 168.23 g/mol | C10H16O2 | 5 MG
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Cis/trans-nepetalactol is an iridoid natural product found in Actinidia polygama (silver vine). It is reported to be a major cat attractant and to exhibit mosquito-repellent activity. Supplied for research use, the compound is typically provided as a purified solid useful for behavioral, ecological, and chemical studies.
- Natural iridoid compound from silver vine.
- Acts as a cat attractant and insect repellent.
- Provided as a purified research-grade material (95.0% purity).
- Available in small milligram pack sizes suitable for assays.
- Useful as a reference standard or reagent in behavioral and chemical ecology studies.
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Medchemexpress LLC N-(4,6-dimethyl-2-pyridinyl)-4-[[4-(trifluoromethyl)phenyl]methyl]piperazine-1-carbothioamide | 1916571-90-8 | 99.7% | 408.48 g/mol | C20H23F3N4S | 1 ML
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NCT-503 is a small-molecule inhibitor of phosphoglycerate dehydrogenase (PHGDH) used in biochemical and cellular research. It exhibits an in vitro IC50 of 2.5 μM and is provided as either a solid or a ready-to-use 10 mM solution in DMSO for cell-based and biochemical assays.
- Inhibits PHGDH with an IC50 of 2.5 μM.
- High purity (99.69%).
- Molecular weight 408.48 g/mol.
- Available as a 10 mM DMSO solution (1 mL) and multiple solid sizes.
- Soluble in DMSO (50 mg/mL) and ethanol (13.33 mg/mL) with recommended handling.
- Recommended storage: powder at -20°C (long term) or 4°C; solutions at -80°C or -20°C.
- Intended for research use only.
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Selleck Chemical LLC VE-821
VE-821(ATR inhibitor IV) is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM in cell-free assays shows inhibition of H2AX phosphorylation minimal activity against PIKKs ATM DNA-PK mTOR and PI3K
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