Azepines
Apexbio Technology LLC Oxcarbazepine 28721-07-5 10mM (in 1mL DMSO)
Oxcarbazepine (CAS 28721-07-5) is a small molecule that modulates voltage-gated sodium channels a critical target in neuronal excitability studies It impedes the association of [3H]batrachotoxin ([3H]BTX) with sodium channels demonstrating an IC50 of 160 M and restricts sodium ion influx as indicated by inhibition of 22Na uptake into rat brain synaptosomes with an IC50 of approximately 100 M These properties make oxcarbazepine valuable for investigating sodium channel function and regulation in neuropharmacology and for exploring mechanisms underlying neuronal signaling and excitotoxicity
Apexbio Technology LLC Oxcarbazepine 28721-07-5 50mg
Oxcarbazepine (CAS 28721-07-5) is a small molecule that modulates voltage-gated sodium channels a critical target in neuronal excitability studies It impedes the association of [3H]batrachotoxin ([3H]BTX) with sodium channels demonstrating an IC50 of 160 M and restricts sodium ion influx as indicated by inhibition of 22Na uptake into rat brain synaptosomes with an IC50 of approximately 100 M These properties make oxcarbazepine valuable for investigating sodium channel function and regulation in neuropharmacology and for exploring mechanisms underlying neuronal signaling and excitotoxicity
Medchemexpress LLC Carbamazepine | 298-46-4 | MFCD00005073 | 99.95% | 1 ML
Carbamazepine is an orally active sodium ion channel blocker and HDAC inhibitor. It is used for research related to epilepsy and neuropathic pain, blocking voltage-gated Na+, Ca2+, and K+ channels. Its anticonvulsant properties make it suitable for various neurological studies.
- Orally active sodium ion channel blocker
- HDAC inhibitor with IC50 of 2 μM
- Blocks voltage-gated Na+, Ca2+, and K+ channels
- Used in epilepsy and neuropathic pain research
- Anticonvulsant properties
Medchemexpress LLC Carbamazepine | 298-46-4 | 99.95% | 236.27 | 100 MG
Carbamazepine is an orally active pressure-sensitive sodium ion channel blocker with an IC50 of 131 μM. It blocks voltage-gated Na+, Ca2+, and K+ channels and is also a HDAC inhibitor (IC50: 2 μM). Carbamazepine is an anticonvulsant and can be used for research of epilepsy and neuropathic pain.
- Orally active pressure-sensitive sodium ion channel blocker
- Blocks voltage-gated Na+, Ca2+, and K+ channels
- Acts as a HDAC inhibitor
- Anticonvulsant properties
- Useful for research into epilepsy
- Useful for research into neuropathic pain
Apexbio Technology LLC Carbamazepine 298-46-4 10mM (in 1mL DMSO)
Carbamazepine (CAS 298-46-4) is a tricyclic compound that functions primarily as a voltage-gated sodium channel blocker By stabilizing the inactivated state of sodium channels it reduces neuronal excitability and inhibits repetitive firing of action potentials Carbamazepine is widely utilized in research to model and investigate mechanisms of anticonvulsant activity synaptic transmission modulation and ion channel pharmacology Its established action on sodium channels makes it a valuable tool for studies involving neuronal hyperexcitability and related neurological disorders
Apexbio Technology LLC Carbamazepine 298-46-4 50mg
Carbamazepine (CAS 298-46-4) is a tricyclic compound that functions primarily as a voltage-gated sodium channel blocker By stabilizing the inactivated state of sodium channels it reduces neuronal excitability and inhibits repetitive firing of action potentials Carbamazepine is widely utilized in research to model and investigate mechanisms of anticonvulsant activity synaptic transmission modulation and ion channel pharmacology Its established action on sodium channels makes it a valuable tool for studies involving neuronal hyperexcitability and related neurological disorders
Medchemexpress LLC Carbamazepine (Standard) | 298-46-4 | 100.0% | 100 MG
Carbamazepine (Standard) is the analytical standard of Carbamazepine, intended for research and analytical applications. It is an orally active pressure-sensitive sodium ion channel blocker, blocking voltage gated Na+, Ca2+, and K+ channels, and also acts as an HDAC inhibitor. It is an anticonvulsant used for research of epilepsy and neuropathic pain, commonly utilized in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard for Carbamazepine
- Intended for research and analytical applications
- Orally active pressure-sensitive sodium ion channel blocker
- Blocks voltage gated Na+, Ca2+, and K+ channels
- Acts as an HDAC inhibitor
- Anticonvulsant for epilepsy and neuropathic pain research
- Used in HPLC, GC, and MS experiments
Selleck Chemical LLC Carbamazepine S1693-1g
Carbamazepine (Carbatrol NSC 169864) is a sodium channel blocker with IC50 of 131 M in rat brain synaptosomes
Selleck Chemical LLC Carbamazepine-50mg
Carbamazepine (Carbatrol, NSC 169864) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.
Selleck Chemical LLC Eslicarbazepine Acetate S4657-100mg
Eslicarbazepine Acetate (BIA 2093 Zebinix Exalief Stedesa Aptiom) an antiepileptic drug is a dual a dual Inhibitor of -Secretase and voltage-gated sodium channel
Medchemexpress LLC Carbamazepine (standard) | 298-46-4 | 99.97% | 50 MG
Carbamazepine (Standard) is an orally active, pressure-sensitive sodium ion channel blocker, demonstrating an IC50 of 131 μM. This compound also blocks voltage-gated Na+, Ca2+, and K+ channels, and acts as a histone deacetylase (HDAC) inhibitor with an IC50 of 2 μM. It is primarily used as an anticonvulsant in research settings. This analytical standard is suitable for qualitative, quantitative, and methodological research experiments, including applications in HPLC, GC, and MS.
- Functions as an anticonvulsant for epilepsy and neuropathic pain research.
- Blocks voltage-gated sodium, calcium, and potassium channels.
- Inhibits histone deacetylase (HDAC).
- Supplied as an analytical standard for various research applications.
Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | C15H12N2O2 | 50 MG
Oxcarbazepine is a sodium channel blocker that significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits anti-cancer and anticonvulsant effects.
- Sodium channel blocker
- Significantly inhibits glioblastoma cell growth
- Induces apoptosis or G2/M arrest in glioblastoma cell lines
- Anti-cancer effects
- Anticonvulsant effects
Medchemexpress LLC Carbamazepine (Standard) | 298-46-4 | 99.9% | 25 MG
Carbamazepine (Standard) is the analytical standard of Carbamazepine, intended for research and analytical applications. It is an orally active pressure-sensitive sodium ion channel blocker with an IC50 of 131 μM. This anticonvulsant can be used for research related to epilepsy and neuropathic pain.
- Analytical standard of Carbamazepine
- Orally active pressure-sensitive sodium ion channel blocker (IC50: 131 μM)
- Blocks voltage-gated Na+, Ca2+, and K+ channels
- Acts as an HDAC inhibitor (IC50: 2 μM)
- Can be used for research related to epilepsy and neuropathic pain
- Commonly used in qualitative, quantitative, and methodological research experiments (HPLC, GC, MS)
Medchemexpress LLC Eslicarbazepine acetate | 236395-14-5 | 99.9% | 500 MG
Eslicarbazepine acetate (BIA 2-093) is an antiepileptic agent that functions as a dual inhibitor of β-Secretase and voltage-gated sodium channels. It is a prodrug that is converted to eslicarbazepine, an active metabolite of oxcarbazepine, sharing an identical mechanism of action. This compound may offer improved tolerability compared to oxcarbazepine by not producing as high peak levels of (S)-(+)-licarbazepine immediately after dosing.
- Functions as an antiepileptic agent
- Dual inhibitor of β-Secretase and voltage-gated sodium channels
- Prodrug activated to eslicarbazepine
- Mechanism of action identical to oxcarbazepine
- May improve tolerability over oxcarbazepine
- Targets beta-secretase and sodium channel pathways
- Involved in neuronal signaling and membrane transporter/ion channel pathways
Selleck Chemical LLC Oxcarbazepine S1391-10mg
Oxcarbazepine (GP47680) inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 M and also inhibits the influx of 22Na into rat brain synaptosomes with IC50 about 100 M
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