Azepines
Oxcarbazepine 28721-07-5 10mM (in 1mL DMSO)
Oxcarbazepine (CAS 28721-07-5) is a small molecule that modulates voltage-gated sodium channels a critical target in neuronal excitability studies It impedes the association of [3H]batrachotoxin ([3H]BTX) with sodium channels demonstrating an IC50 of 160 M and restricts sodium ion influx as indicated by inhibition of 22Na uptake into rat brain synaptosomes with an IC50 of approximately 100 M These properties make oxcarbazepine valuable for investigating sodium channel function and regulation in neuropharmacology and for exploring mechanisms underlying neuronal signaling and excitotoxicity
Oxcarbazepine 28721-07-5 50mg
Oxcarbazepine (CAS 28721-07-5) is a small molecule that modulates voltage-gated sodium channels a critical target in neuronal excitability studies It impedes the association of [3H]batrachotoxin ([3H]BTX) with sodium channels demonstrating an IC50 of 160 M and restricts sodium ion influx as indicated by inhibition of 22Na uptake into rat brain synaptosomes with an IC50 of approximately 100 M These properties make oxcarbazepine valuable for investigating sodium channel function and regulation in neuropharmacology and for exploring mechanisms underlying neuronal signaling and excitotoxicity
Carbamazepine 298-46-4 10mM (in 1mL DMSO)
Carbamazepine (CAS 298-46-4) is a tricyclic compound that functions primarily as a voltage-gated sodium channel blocker By stabilizing the inactivated state of sodium channels it reduces neuronal excitability and inhibits repetitive firing of action potentials Carbamazepine is widely utilized in research to model and investigate mechanisms of anticonvulsant activity synaptic transmission modulation and ion channel pharmacology Its established action on sodium channels makes it a valuable tool for studies involving neuronal hyperexcitability and related neurological disorders
Carbamazepine 298-46-4 50mg
Carbamazepine (CAS 298-46-4) is a tricyclic compound that functions primarily as a voltage-gated sodium channel blocker By stabilizing the inactivated state of sodium channels it reduces neuronal excitability and inhibits repetitive firing of action potentials Carbamazepine is widely utilized in research to model and investigate mechanisms of anticonvulsant activity synaptic transmission modulation and ion channel pharmacology Its established action on sodium channels makes it a valuable tool for studies involving neuronal hyperexcitability and related neurological disorders
Selleck Chemical LLC Carbamazepine S1693-1g
Carbamazepine (Carbatrol NSC 169864) is a sodium channel blocker with IC50 of 131 M in rat brain synaptosomes
Selleck Chemical LLC Carbamazepine-50mg
Carbamazepine (Carbatrol, NSC 169864) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.
Selleck Chemical LLC Eslicarbazepine Acetate S4657-100mg
Eslicarbazepine Acetate (BIA 2093 Zebinix Exalief Stedesa Aptiom) an antiepileptic drug is a dual a dual Inhibitor of -Secretase and voltage-gated sodium channel
Selleck Chemical LLC Oxcarbazepine S1391-10mg
Oxcarbazepine (GP47680) inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 M and also inhibits the influx of 22Na into rat brain synaptosomes with IC50 about 100 M
Eslicarbazepine acetate 236395-14-5 100mg
Eslicarbazepine acetate (CAS 236395-14-5) is an orally administered anticonvulsant prodrug that undergoes rapid first-pass hydrolysis to yield eslicarbazepine its pharmacologically active metabolite Eslicarbazepine predominantly modulates neuronal excitability by stabilizing the inactivated state of voltage-gated sodium channels thereby reducing sustained repetitive neuronal firing associated with seizure activity While approved for adjunctive treatment in partial-onset seizures eslicarbazepine acetate is frequently utilized in research to investigate the pathophysiology of epileptic disorders and to study sodium channel-mediated neuronal signaling
Eslicarbazepine acetate 236395-14-5 10mM (in 1mL DMSO)
Eslicarbazepine acetate (CAS 236395-14-5) is an orally administered anticonvulsant prodrug that undergoes rapid first-pass hydrolysis to yield eslicarbazepine its pharmacologically active metabolite Eslicarbazepine predominantly modulates neuronal excitability by stabilizing the inactivated state of voltage-gated sodium channels thereby reducing sustained repetitive neuronal firing associated with seizure activity While approved for adjunctive treatment in partial-onset seizures eslicarbazepine acetate is frequently utilized in research to investigate the pathophysiology of epileptic disorders and to study sodium channel-mediated neuronal signaling