Cycloheptathiophenes
Apexbio Technology LLC Quetiapine Fumarate 111974-72-2 100mg
Quetiapine Fumarate (CAS 111974-72-2) is a small-molecule atypical antipsychotic with antagonistic activity at dopamine (D1 D2) serotonin (5-HT1A 5-HT2) and adrenergic ( 1 2) receptors In vitro it exhibits affinity for multiple neurotransmitter receptors with dopamine-2 binding characteristics similar to clozapine Preclinical in vivo studies demonstrate antipsychotic effects minimal extrapyramidal side effects and a lower propensity for sustained prolactin elevation Quetiapine has been shown to modulate neurotrophin expression and restore hippocampal neurogenesis following chronic stress in animal models supporting its value in neuropsychiatric and neuropharmacological research
Medchemexpress LLC Fesoterodine (fumarate) | 286930-03-8 | MFCD09835695 | ≥98% | 574.67 | 10 MG
Fesoterodine fumarate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist. It is used for the overactive bladder (OAB).
- Orally active
- Nonsubtype selective
- Competitive muscarinic receptor (mAChR) antagonist
- Targets mAChR
- Used for overactive bladder (OAB)
- Research areas include neurological disease, metabolic disease, and cancer
Medchemexpress LLC Vonoprazan Fumarate (TAK-438) | 881681-01-2 | MFCD18633280 | C21H20FN3O6S | 1 ML
Vonoprazan Fumarate (TAK-438) is a potent and orally active potassium-competitive acid blocker (P-CAB) developed for research into acid-related diseases such as gastroesophageal reflux disease and peptic ulcer disease. It functions as a proton pump inhibitor (PPI) and exhibits antisecretory activity.
- Potent and orally active potassium-competitive acid blocker (P-CAB)
- Proton pump inhibitor (PPI)
- Antisecretory activity
- Inhibits H+,K+-ATPase activity with an IC50 of 19 nM at pH 6.5
Medchemexpress LLC Monoethyl fumarate | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 | C6H8O4 | 5 G
Monoethyl fumarate is the monoethyl ester of fumaric acid used primarily in research as an activator of the Nrf2 pathway and as a preservative and polymerization agent for macromolecular materials. It is provided as a high-purity solid suitable for biochemical and materials applications.
- Activates the Nrf2 signaling pathway relevant for redox research.
- High purity (≈99.6%), suitable for analytical and research use.
- Solid form with defined storage stability under recommended conditions.
- Useful as a preservative and polymerization agent for macromolecular materials.
- Available in multiple pack sizes and solution formats for flexible use.
Apexbio Technology LLC Fesoterodine Fumarate 286930-03-8 50mg
Fesoterodine Fumarate (CAS 286930-03-8) is a synthetic antimuscarinic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors particularly the M3 subtype in the bladder detrusor muscle By inhibiting these receptors the compound modulates involuntary bladder contractions reducing symptoms associated with overactive bladder syndrome such as urgency and frequency Fesoterodine Fumarate is utilized in biomedical research to study cholinergic signaling mechanisms involved in urinary function and to explore pharmacological interventions targeting muscarinic pathways in urological disorders
![Medchemexpress LLC 3aH-indole-3a-carboxylic acid, 1-([1,1'-biphenyl]-4-ylmethyl)-hexahydro-3-substituted, sodium salt | 2070009-45-7 | 98.7% | 440.47 g/mol | C25H25N2NaO4 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000215663.png-250.jpg)
Medchemexpress LLC 3aH-indole-3a-carboxylic acid, 1-([1,1'-biphenyl]-4-ylmethyl)-hexahydro-3-substituted, sodium salt | 2070009-45-7 | 98.7% | 440.47 g/mol | C25H25N2NaO4 | 10 MG
Fumarate hydratase-IN-2 sodium salt is a cell-permeable, competitive inhibitor of fumarate hydratase (Ki = 4.5 μM). Supplied as the sodium salt as a white to off-white solid, it is intended for biochemical and cell-based research, including studies of metabolic regulation and nutrient-dependent cytotoxicity.
- Cell-permeable competitive inhibitor of fumarate hydratase (Ki = 4.5 μM).
- Sodium salt form for improved solubility in aqueous and polar solvents.
- High purity (98.7%) appropriate for research use.
- Soluble in DMSO (10.66 mg/mL) and water (6.25 mg/mL) with warming and sonication.
- Stable when stored sealed away from moisture; follow solvent storage recommendations.
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 1 ML
Monoethyl fumarate is the monoethyl ester of fumaric acid used as a research reagent. It acts as an activator of Nrf2 and is employed as a preservative and polymerization agent for macromolecular materials. The compound is available as a ready-to-use 10 mM solution in DMSO or as a bulk solid and is provided with analytical documentation confirming high purity.
TARGETMOL CHEMICALS INC Org-13011 fumarate 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Org-13011 fumarate1 is an agonist of the 5-HT1A receptor and can be used to study neurological disorders. Purity 98.61%
Selleck Chemical LLC Ensitrelvir fumarate-10MM/1ML
S-217622 (Ensitrelvir fumarate) is the first orally active non-covalent non-peptidic SARS-CoV-2 3CL protease inhibitor with IC50 of 13 nM
Medchemexpress LLC Ibutilide (fumarate) | 122647-32-9 | 99.7% | 100 MG
Ibutilide fumarate is an action potential-prolonging antiarrhythmic agent. It is a potent blocker of the rapidly activating delayed rectifier K+ current (IKr) in AT-1 cells, playing a role in cardiac repolarization. This product is suitable for research applications in cardiac physiology and pharmacology.
- Potent IKr blocker
- Prolongs cardiac repolarization
- Relevant for studies on atrial tumor myocytes
- Useful in research related to congestive heart failure models
Medchemexpress LLC 2-butenedioic acid (2e)-, 1-[2-(diethylamino)-2-oxoethyl] 4-methyl ester | 1208229-58-6 | 99.8% | 243.26 | 1 ML
Tepilamide fumarate is an oral fumaric acid ester that acts as a proagent of Monomethyl fumarate. It is used in the research of moderate to severe chronic plaque psoriasis and can enhance the effectiveness of oncolytic viruses. In vitro studies show that it makes 786-0 cancer cells more susceptible to infection by VSV∆51, leading to increased virus replication, and selectively promotes oncolytic virus infection in cancer cells without affecting healthy tissues.
- Oral fumaric acid ester
- Acts as a proagent of monomethyl fumarate
- Used in research of moderate to severe chronic plaque psoriasis
- Enhances the effectiveness of oncolytic viruses
- Increases susceptibility of cancer cells to viral infection
- Selectively promotes oncolytic virus infection in cancer cells
Apexbio Technology LLC Quetiapine Fumarate 111974-72-2 50mg
Quetiapine Fumarate (CAS 111974-72-2) is a small-molecule atypical antipsychotic with antagonistic activity at dopamine (D1 D2) serotonin (5-HT1A 5-HT2) and adrenergic ( 1 2) receptors In vitro it exhibits affinity for multiple neurotransmitter receptors with dopamine-2 binding characteristics similar to clozapine Preclinical in vivo studies demonstrate antipsychotic effects minimal extrapyramidal side effects and a lower propensity for sustained prolactin elevation Quetiapine has been shown to modulate neurotrophin expression and restore hippocampal neurogenesis following chronic stress in animal models supporting its value in neuropsychiatric and neuropharmacological research
Medchemexpress LLC Ketotifen | 34580-13-7 | 99.7% | 50 MG
Ketotifen is an orally active, second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. It can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Additionally, it exhibits antiviral activity against SARS-CoV-2 and Influenza virus. It is used in the research of autoimmune encephalomyelitis (EAE) and for asthma attack prevention.
- Orally active, second-generation noncompetitive histamine 1 (H1) receptor blocker
- Mast cell stabilizer
- Blocks 6-phosphogluconate dehydrogenase (PGD) in vitro
- Antiviral activity against SARS-CoV-2 and Influenza virus
- Used in research of autoimmune encephalomyelitis (EAE)
- Used for asthma attack prevention
Medchemexpress LLC Pirepemat fumarate (IRL752 fumarate) | 2251806-70-7 | 98.3% | 329.30 | 1 ML
Pirepemat (IRL752) fumarate is a cognition-promoting agent that preferentially acts on the cortex, affecting catecholamine transmission. It is currently being investigated for its potential use in the treatment of Parkinson's disease.
- A cortical-preferring cognition-promoting agent.
- Used for the study of Parkinson's disease.
- Displays highest in vitro affinities for 5-HT and NA-related targets.