Cycloheptathiophenes
Medchemexpress LLC Ro60-0175 fumarate | 169675-09-6 | MFCD06798313 | 99.5% | 342.75 g/mol | C15H16ClFN2O4 | 1 ML
Ro60-0175 fumarate is a selective agonist of the serotonin 5-HT2C receptor used in neuroscience and pharmacology research. It is provided as a ready-to-use 10 mM solution in DMSO (1 mL) and in solid quantities; reported purity is 99.47%, with molecular formula C15H16ClFN2O4 and molecular weight 342.75 g/mol.
- Selective 5-HT2C receptor agonist for pharmacology studies.
- Available as 10 mM solution in DMSO (1 mL) and as solids (5, 10, 50 mg).
- High purity (~99.5%) suitable for research applications.
- Soluble in DMSO; in vitro solubility approximately 100 mg/mL.
- Storage guidance provided for powder and solutions to preserve stability.
Medchemexpress LLC Fumarate hydratase-IN-2 (sodium salt) | 2070009-45-7 | 98.7% | 440.47 | C25H25N2NaO4 | 100 MG
Fumarate hydratase-IN-2 (sodium salt) is a cell-permeable, competitive inhibitor of fumarate hydratase with a reported Ki of 4.5 μM and nutrient-dependent cytotoxicity. Supplied as a sodium salt, it is intended for biochemical and cell-based studies probing fumarate hydratase activity and related metabolic pathways.
- Cell-permeable, competitive inhibitor of fumarate hydratase (Ki = 4.5 μM).
- Reported nutrient-dependent cytotoxicity in cell assays.
- High purity suitable for research use (LCMS 98.7%).
- Molecular weight 440.47; formula C25H25N2NaO4.
- Available in small-scale solid quantities for assay preparation (for example, 100 mg).
Medchemexpress LLC Ocifisertib (fumarate) | 1616420-30-4 | 99.3% | 650.72 g/mol | C37H38N4O7 | 100MG
Ocifisertib (fumarate) is the fumarate salt form of a potent and selective ATP-competitive inhibitor of polo-like kinase 4 (PLK4) supplied for laboratory research. It is provided as a solid research reagent with molecular formula C37H38N4O7 and molecular weight 650.72 g/mol.
Medchemexpress LLC Ketotifen (fumarate) | 34580-14-8 | 99.9% | 1 ML
Ketotifen fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. It can block 6-phosphogluconate dehydrogenase (PGD) in vitro and has antiviral activity against SARS-CoV-2 and Influenza virus. It can be used for the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention.
- Orally active second-generation noncompetitive H1 receptor blocker
- Mast cell stabilizer
- Blocks 6-phosphogluconate dehydrogenase (PGD) in vitro
- Exhibits antiviral activity against SARS-CoV-2 and influenza virus
- Reduces end organ damage and mortality in mice infected with influenza virus
- Reduces encephalomyelitis (EAE) prevalence and severity
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1,4-diethyl ester | 623-91-6 | 99.0% | 172.18 | 10 MM/ML
Diethyl fumarate (Standard) is the analytical standard of Diethyl fumarate. This product is intended for research and analytical applications. It is a decomposition product of Malathion 9 (a pesticide) and a reactant in the Diels-Alder reaction. It is a reputed skin irritant and can cause non-immunologic contact urticaria on skin. Diethyl fumarate and Curcumin hybridize to exert neuroprotective effects.
- Serves as an analytical standard and reference standard supplied assay.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Reactant in the Diels-Alder reaction.
- Exerts neuroprotective effects when hybridized with Curcumin.
Medchemexpress LLC Ketotifen | 34580-13-7 | 99.7% | 100 MG
Ketotifen (HC 20-511) is an orally active, second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. It can block 6-phosphogluconate dehydrogenase (PGD) in vitro and demonstrates antiviral activity against SARS-CoV-2 and Influenza virus, making it suitable for various research applications.
- Orally active compound
- Functions as a second-generation noncompetitive histamine 1 (H1) receptor blocker
- Acts as a mast cell stabilizer
- Blocks 6-phosphogluconate dehydrogenase (PGD) in vitro
- Demonstrates antiviral activity against SARS-CoV-2
- Demonstrates antiviral activity against Influenza virus
- Used in research for autoimmune encephalomyelitis (EAE)
- Used in research for asthma attack prevention
Medchemexpress LLC Clemastine fumarate | 14976-57-9 | 99.96% | 1 ML
Clemastine fumarate is an orally active, blood-brain barrier-permeable H1 histamine receptor antagonist with potent antiallergic effects. It also antagonizes muscarinic acetylcholine receptors (mAChR), particularly the M1 and M4 subtypes. Beyond antihistamine effects, Clemastine fumarate shows various pharmacological activities.
- Promoting remyelination in the central nervous system
- Activating autophagy and pyroptosis
- Exerting anti-apoptotic and neuroprotective effects
- Suppressing inflammation