Cycloheptathiophenes
Apexbio Technology LLC Clemastine Fumarate 14976-57-9 500mg
Clemastine Fumarate (CAS 14976-57-9) is a small molecule that functions as a selective antagonist of the histamine H1 receptor It demonstrates high affinity for the receptor with an inhibitory concentration (IC50) of 3 nM By blocking histamine H1 receptor-mediated signaling clemastine fumarate is utilized in research to study histaminergic pathways and allergic responses It is also employed to investigate the pharmacological modulation of H1 receptor activity in various cellular and in vivo models
Medchemexpress LLC Fumarate hydratase-IN-2 (sodium salt) | 2070009-45-7 | 98.7% | 440.47 | C25H25N2NaO4 | 100 MG
Fumarate hydratase-IN-2 (sodium salt) is a cell-permeable, competitive inhibitor of fumarate hydratase with a reported Ki of 4.5 μM and nutrient-dependent cytotoxicity. Supplied as a sodium salt, it is intended for biochemical and cell-based studies probing fumarate hydratase activity and related metabolic pathways.
- Cell-permeable, competitive inhibitor of fumarate hydratase (Ki = 4.5 μM).
- Reported nutrient-dependent cytotoxicity in cell assays.
- High purity suitable for research use (LCMS 98.7%).
- Molecular weight 440.47; formula C25H25N2NaO4.
- Available in small-scale solid quantities for assay preparation (for example, 100 mg).
Apexbio Technology LLC Formoterol fumarate 43229-80-7 10mg
Formoterol fumarate (CAS 43229-80-7) is a long-acting 2-adrenergic receptor agonist that selectively binds to 2-adrenergic receptors on bronchial smooth muscle inducing relaxation and bronchodilation Through this mechanism it modulates airway smooth muscle tone leading to sustained improvement in airflow This compound is widely utilized in research exploring pathways of bronchoconstriction receptor signaling and the pharmacological management of obstructive airway diseases such as asthma and chronic obstructive pulmonary disease (COPD)
Medchemexpress LLC Tepilamide fumarate | 1208229-58-6 | 99.8% | 243.26 | 100 MG
Tepilamide fumarate is an oral fumaric acid ester that acts as a proagent of Monomethyl fumarate. It is used in the research of moderate to severe chronic plaque psoriasis and can enhance the effectiveness of oncolytic viruses.
- Oral fumaric acid ester
- Proagent of Monomethyl fumarate
- Enhances effectiveness of oncolytic viruses
- Selectively promotes oncolytic virus infection in cancer cells without affecting healthy tissues
- Used in research for moderate to severe chronic plaque psoriasis
- Potential to enhance virus-based therapy
- Solid, white to off-white appearance
Medchemexpress LLC Ketotifen (fumarate) | 34580-14-8 | 99.9% | 1 ML
Ketotifen fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. It can block 6-phosphogluconate dehydrogenase (PGD) in vitro and has antiviral activity against SARS-CoV-2 and Influenza virus. It can be used for the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention.
- Orally active second-generation noncompetitive H1 receptor blocker
- Mast cell stabilizer
- Blocks 6-phosphogluconate dehydrogenase (PGD) in vitro
- Exhibits antiviral activity against SARS-CoV-2 and influenza virus
- Reduces end organ damage and mortality in mice infected with influenza virus
- Reduces encephalomyelitis (EAE) prevalence and severity
TARGETMOL CHEMICALS INC APLINDORE FUMARATE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors and low affinity for dopamine D4 5-hydroxytryptophan (5-HT2) and (alpha)1-adrenergic receptors.Aplindore Fumarate is used in the study of Parkinson's disease and schizophrenia. Fumarate can be used to study Parkinson's and schizophrenia. purity: 100%
TARGETMOL CHEMICALS INC RUPATADINE FUMARATE 500MG
Also available in 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM. purity: 99%
TARGETMOL CHEMICALS INC KT-362 FUMARATE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels potassium channels and sodium channels.KT-362 fumarate causes vasodilation by affecting intracellular calcium mobilization in atrial muscle cells.KT-362 fumarate has a relaxing effect on femoral and basilar artery strips in rabbits. purity: 99%
Medchemexpress LLC VUF11207 fumarate | 1785665-61-3 | 99.9% | 586.65 | 25 MG
VUF11207 fumarate is a CXCR7 agonist that specifically binds to CXCR7. It reduces CXCL12-mediated osteoclastogenesis and bone resorption by inhibiting ERK phosphorylation. This product is for research use only.
- Specifically binds to CXCR7
- Reduces CXCL12-mediated osteoclastogenesis
- Inhibits bone resorption
- Suppresses phosphorylation of ERK
- Inhibits RANKL- and TNF-α-induced osteoclastogenesis
- Inhibits LPS-induced osteoclastogenesis and bone resorption
Medchemexpress LLC Tepilamide fumarate | 1208229-58-6 | 99.8% | 243.26 | 50 MG
Tepilamide fumarate is an oral fumaric acid ester that acts as a proagent of Monomethyl fumarate. It is used in the research of moderate to severe chronic plaque psoriasis and can enhance the effectiveness of oncolytic viruses.
- Acts as a proagent of Monomethyl fumarate
- Used in research for moderate to severe chronic plaque psoriasis
- Enhances the effectiveness of oncolytic viruses
- Increases susceptibility of cancer cells to VSV∆51 infection
TARGETMOL CHEMICALS INC TENOFOVIR DISOPROXIL FUM 100MG
Also available in 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug fumaric acid salt form of tenofovir a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is prescribed to treat HIV and chronic hepatitis B virus (HBV) in adults. purity: 99%
Cayman Chemical DImethyl fumarate 250g
A lipophilic electrophile that has profound effects on oxidative and immunological pathways; activates the transcription factor Nrf2, resulting in heme oxygenase-1 expression and increased glutathione levels; suppresses the expression of pro-inflammatory cytokines and inhibits angiogenesis
Medchemexpress LLC Ketotifen | 34580-13-7 | 99.7% | 100 MG
Ketotifen (HC 20-511) is an orally active, second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. It can block 6-phosphogluconate dehydrogenase (PGD) in vitro and demonstrates antiviral activity against SARS-CoV-2 and Influenza virus, making it suitable for various research applications.
- Orally active compound
- Functions as a second-generation noncompetitive histamine 1 (H1) receptor blocker
- Acts as a mast cell stabilizer
- Blocks 6-phosphogluconate dehydrogenase (PGD) in vitro
- Demonstrates antiviral activity against SARS-CoV-2
- Demonstrates antiviral activity against Influenza virus
- Used in research for autoimmune encephalomyelitis (EAE)
- Used in research for asthma attack prevention
Selleck Chemical LLC Zilurgisertib fumarate-25MG
Zilurgisertib fumarate(INCB-000928 fumarate NBU-928 fumarate) is a selective ALK 2 inhibitor It is under development for the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva