Cycloheptathiophenes
Medchemexpress LLC Fumarate hydratase-IN-2 (sodium salt) | 2070009-45-7 | 98.7% | 440.47 | C25H25N2NaO4 | 100 MG
Fumarate hydratase-IN-2 (sodium salt) is a cell-permeable, competitive inhibitor of fumarate hydratase with a reported Ki of 4.5 μM and nutrient-dependent cytotoxicity. Supplied as a sodium salt, it is intended for biochemical and cell-based studies probing fumarate hydratase activity and related metabolic pathways.
- Cell-permeable, competitive inhibitor of fumarate hydratase (Ki = 4.5 μM).
- Reported nutrient-dependent cytotoxicity in cell assays.
- High purity suitable for research use (LCMS 98.7%).
- Molecular weight 440.47; formula C25H25N2NaO4.
- Available in small-scale solid quantities for assay preparation (for example, 100 mg).
Selleck Chemical LLC Ibutilide Fumarate S2118-10mg
Ibutilide Fumarate (U-70226E Corvert Fumarate) is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current which prolongs action potential and refractory period of myocardial cells
TARGETMOL CHEMICALS INC TENOFOVIR DISOPROXIL FUM 100MG
Also available in 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug fumaric acid salt form of tenofovir a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is prescribed to treat HIV and chronic hepatitis B virus (HBV) in adults. purity: 99%
Apexbio Technology LLC Clemastine Fumarate 14976-57-9 500mg
Clemastine Fumarate (CAS 14976-57-9) is a small molecule that functions as a selective antagonist of the histamine H1 receptor It demonstrates high affinity for the receptor with an inhibitory concentration (IC50) of 3 nM By blocking histamine H1 receptor-mediated signaling clemastine fumarate is utilized in research to study histaminergic pathways and allergic responses It is also employed to investigate the pharmacological modulation of H1 receptor activity in various cellular and in vivo models
Medchemexpress LLC Ensitrelvir fumarate | 2757470-18-9 | 99.99% | C26H21ClF3N9O6 | 25 MG
Ensitrelvir fumarate is an orally active, non-covalent, and non-peptidic SARS-CoV-2 3CL protease inhibitor. It demonstrates significant inhibitory activity against various SARS-CoV-2 variants and has shown to inhibit intrapulmonary replication of SARS-CoV-2 in mice.
- First orally active non-covalent, non-peptidic SARS-CoV-2 3CL protease inhibitor
- Shows EC50 values of approximately 0.4 μM for wild-type and Alpha, Beta, Gamma, and Delta SARS-CoV-2 variants
- Inhibits intrapulmonary replication of SARS-CoV-2 in mice
- For research use only
Apexbio Technology LLC Formoterol fumarate 43229-80-7 50mg
Formoterol fumarate (CAS 43229-80-7) is a long-acting 2-adrenergic receptor agonist that selectively binds to 2-adrenergic receptors on bronchial smooth muscle inducing relaxation and bronchodilation Through this mechanism it modulates airway smooth muscle tone leading to sustained improvement in airflow This compound is widely utilized in research exploring pathways of bronchoconstriction receptor signaling and the pharmacological management of obstructive airway diseases such as asthma and chronic obstructive pulmonary disease (COPD)
Medchemexpress LLC Ibutilide (fumarate) | 122647-32-9 | 99.7% | 5 MG
Ibutilide fumarate (U70226E) is an action potential-prolonging antiarrhythmic agent. It acts as a potent blocker of the rapidly activating delayed rectifier K⁺ current (IKr) in AT-1 cells. This compound is intended for research use only.
- Potent IKr blocker with an EC50 value of 20 nM in AT-1 cells.
- Blocks IKr in cells expressing HERG+MDR1*1 to the same extent as HERG alone.
- Prolongs cardiac repolarization in vitro and in vivo.
- Appears as a white to off-white solid.
- Recommended storage for solid: 4°C, sealed, away from moisture.
- Recommended storage in solvent: -80°C for 6 months, or -20°C for 1 month.
Medchemexpress LLC Ocifisertib (fumarate) | 1616420-30-4 | 99.6% | 650.7 g/mol | C37H38N4O7 | 10MM 1ML
Ocifisertib (CFI-400945) fumarate is a potent, selective inhibitor of polo-like kinase 4 (PLK4) used in preclinical and in vitro research. It exhibits subnanomolar binding affinity (Ki ≈ 0.26 nM) and low-nanomolar cellular potency (PLK4 IC50 ≈ 2.8 nM), and has demonstrated antiproliferative activity in multiple cancer cell models.
- Potent PLK4 inhibition with Ki ≈ 0.26 nM and PLK4 IC50 ≈ 2.8 nM.
- Suitable for biochemical kinase assays and cell-based proliferation studies.
- Provided as a 10 mM solution in 1 mL aliquots for convenient screening use.
- Fumarate salt form to support handling and solubility.
- Molecular formula C37H38N4O7; molecular weight 650.7 g/mol.
- High reported purity from third-party suppliers; verify lot certificate before use.
Medchemexpress LLC Monomethyl fumarate-d2 | 253122-44-0 | MFCD00063174 | 98.2% | 132.11 | C5H4D2O4 | 1 MG
Monomethyl fumarate-d2 is the deuterium-labeled form of monomethyl fumarate, provided as a high-purity research chemical and isotopically labeled standard for metabolic, pharmacological, and analytical studies.
- Deuterium-labeled analog for isotope tracing and mass spectrometry.
- High purity suitable for research applications.
- Supplied in milligram quantities for small-scale experiments.
- Useful as a metabolic standard and mechanistic probe.
Apexbio Technology LLC Formoterol fumarate 43229-80-7 10mg
Formoterol fumarate (CAS 43229-80-7) is a long-acting 2-adrenergic receptor agonist that selectively binds to 2-adrenergic receptors on bronchial smooth muscle inducing relaxation and bronchodilation Through this mechanism it modulates airway smooth muscle tone leading to sustained improvement in airflow This compound is widely utilized in research exploring pathways of bronchoconstriction receptor signaling and the pharmacological management of obstructive airway diseases such as asthma and chronic obstructive pulmonary disease (COPD)
Apexbio Technology LLC Fesoterodine Fumarate 286930-03-8 5mg
Fesoterodine Fumarate (CAS 286930-03-8) is a synthetic antimuscarinic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors particularly the M3 subtype in the bladder detrusor muscle By inhibiting these receptors the compound modulates involuntary bladder contractions reducing symptoms associated with overactive bladder syndrome such as urgency and frequency Fesoterodine Fumarate is utilized in biomedical research to study cholinergic signaling mechanisms involved in urinary function and to explore pharmacological interventions targeting muscarinic pathways in urological disorders
Apexbio Technology LLC GR 89696 fumarate 126766-32-3 10mg
GR 89696 fumarate (CAS 126766-32-3) is a selective agonist of the 2-opioid receptor By specifically activating 2 subtypes this small molecule modulates neural signaling pathways implicated in sensory processing particularly pain and pruritus Experimental studies have demonstrated that GR 89696 fumarate induces physiological effects in the nervous system through 2-opioid receptor activation This compound has been widely utilized as a pharmacological tool in the investigation of neurocutaneous disorders and the underlying mechanisms of opioid receptor-mediated modulation of somatosensory functions