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Filtered Search Results
Medchemexpress LLC Lobenzarit | 63329-53-3 | MFCD00866065 | 99.4% | 291.69 | C14H10ClNO4 | 10MG
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Lobenzarit is a small-molecule immunomodulator provided for laboratory research. It exhibits antioxidative activity and is intended for use in in vitro and preclinical studies; consult the supplier COA and SDS for handling, storage, and purity information.
- Immunomodulatory activity
- Antioxidative properties
- High purity: 99.4%
- Available in small mass quantities suitable for research
- Documentation provided: COA and SDS
- Intended for in vitro and preclinical applications
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Medchemexpress LLC 2,4-imidazolidinedione, 1-amino-, hydrochloride (1:1) | 2827-56-7 | MFCD02181047 | 98.0% | 151.55 | C3H6ClN3O2 | 10g
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1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
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Medchemexpress LLC Cobomarsen | 1848257-52-2 | C148H177N52O77P13S13 | 10MG
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Cobomarsen is a locked nucleic acid (LNA)-based antisense oligonucleotide that selectively inhibits microRNA-155 (miR-155). Supplied as a solid (white to off-white) research reagent, it is used in preclinical studies to modulate miR-155-driven signaling and investigate oncology models by affecting pathways such as JAK/STAT, MAPK/ERK, and PI3K/AKT. The sodium salt form offers improved stability; the compound is highly water soluble and requires sealed, moisture-free storage.
- Selective inhibition of miR-155 and related survival pathways
- Suitable for preclinical oncology and lymphoma research
- High aqueous solubility; may require ultrasonication
- Improved stability as the sodium salt compared with the free acid
- Store sealed and protected from moisture; long-term storage in solution at -80 °C
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Medchemexpress LLC Etiocholanolone (5β-Androsterone) | 53-42-9 | 99.5% | 290.44 | 50 MG
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Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity. Etiocholanolone is a less potent neurosteroid positive allosteric modulator (PAM) of the GABAA receptor than its enantiomer form.
- It is the excreted metabolite of testosterone.
- It has anticonvulsant activity.
- It is a less potent neurosteroid positive allosteric modulator of the GABAA receptor than its enantiomer form.
- It exhibits ED50 values of 57.6 and 109.1 mg/kg in the 6-Hz and PTZ tests, respectively.
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Medchemexpress LLC Pyribencarb | 799247-52-2 | MFCD22200855 | ≥95.0% | 361.83 | C18H20ClN3O3 | 50 MG
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Pyribencarb is a benzylcarbamate-class fungicide supplied as a research-grade standard. It acts as a Qo inhibitor of cytochrome b (complex III) in the mitochondrial electron transport chain and shows activity against a broad range of plant pathogenic fungi. The compound is intended for analytical, in vitro antifungal, and mode-of-action studies.
- Inhibits cytochrome b (complex III) via the Qo site, enabling mechanism-of-action research.
- Active against common plant pathogens such as Botrytis cinerea and Sclerotinia sclerotiorum.
- Provided as a solid reference material suitable for analytical assays and standards.
- Storage stability as powder at low temperatures supports long-term archiving.
- Applicable to in vitro antifungal testing and comparative potency studies.
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Medchemexpress LLC SID7970631 | 868224-75-3 | 98.3% | 50 MG
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SID7970631, an isoquinolinone analog, is a potent and selective submicromolar SF-1 inhibitor with an IC50 of 255 nM. It is used for cancer research.
- Potent and selective submicromolar SF-1 inhibitor (IC50 of 255 nM)
- Used for cancer research
- Exhibits a half-maximal cytotoxic effect in CHO-K1 cells
- Dose-dependently inhibits luciferase expression in the SF-1 assay
- Shows cytotoxic effects on H295R/TR SF-1 cells and SW-13 cells
- Molecular weight is 452.46 with the formula C24H24N2O7
- Appears as a white to off-white solid
- Soluble in DMSO at 100 mg/mL
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Medchemexpress LLC LY-3381916 (IDO1-IN-5) | 2166616-75-5 | 99.9% | 396.45 | 1 ML
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LY-3381916 (IDO1-IN-5) is a potent, selective, and brain-penetrated inhibitor of IDO1 activity. It binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. This product is for research use only and not sold to patients.
- Potent, selective, and brain-penetrated inhibitor of IDO1 activity.
- Binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
- No obvious agonism of aryl hydrocarbon receptor (AHR) up to 100 μM.
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eMolecules 959236-79-4 | 8-Iodoquinazoline-2,4(1H,3H)-dione | MFCD09954831 | 100mg
Ambeed | 8-Iodoquinazoline-2,4(1H,3H)-dione | 100mg | 552627626 | A185660 | 959236-79-4 | MFCD09954831 | 288.044 | C8H5IN2O2
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Medchemexpress LLC 1-aminohydantoin hydrochloride | 2827-56-7 | MFCD02181047 | ≥98.0% | 151.55 | C3H6ClN3O2 | 50mg
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1-Aminohydantoin hydrochloride (Standard) is the analytical standard of 1-Aminohydantoin hydrochloride (HY-Y0469) This product is intended for research and analytical applications 1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
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Medchemexpress LLC 1-Aminohydantoin | 6301-02-6 | 115.09 | 100 MG
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1-Aminohydantoin is a Furagin derivative with a molecular weight of 115.09 and a chemical formula of C3H5N3O2. Its CAS number is 6301-02-6. This product is intended for research use only and is not for human use.
- For research use only, not intended for human use.
- Molecular weight of 115.09.
- Chemical formula of C3H5N3O2.
- CAS number 6301-02-6.
- Ships at room temperature in continental US.
- Store under recommended conditions in the Certificate of Analysis.
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Medchemexpress LLC 2-isopropylphenyl N-(2-naphthalen-2-yl)ethyl carbamate | 1354359-53-7 | MFCD20926355 | 99.5% | 333.42 g/mol | C22H23NO2 | 10 MG
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JW480 is a potent, selective carbamate inhibitor of the serine hydrolase KIAA1363 (AADACL1). It is used as a research reagent to probe KIAA1363 function in lipid metabolism and cancer-relevant cellular pathways, and is supplied with characterization data appropriate for biochemical and cellular studies.
- Selective inhibitor of the serine hydrolase KIAA1363.
- Suitable for biochemical and cell-based assays.
- Carbamate-based small-molecule structure for target engagement studies.
- High purity and defined molecular properties for reproducible results.
- Provided with catalog and registry identifiers for traceability.
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Medchemexpress LLC 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt | 150849-52-8 | MFCD01075079 | 98.0% | C19H11IN5NaO8S2 | 10MG
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WST-1 is a water-soluble tetrazolium salt used as a chromogenic reagent to assess cell proliferation and cytotoxicity. It is reduced by cellular mitochondrial dehydrogenases in an NAD(P)H-dependent reaction to form a water-soluble formazan product that can be measured colorimetrically, enabling straightforward viability assays without additional solubilization steps. Handle and store according to supplier SDS and COA recommendations.
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Medchemexpress LLC 1-[(3-methoxyphenyl)methyl]-N-(4-methyl-3-morpholin-4-ylsulfonylphenyl)-3-(4-methylphenyl)pyrazole | 1609564-75-1 | 99.3% | 560.66 | C30H32N4O5S | 5 MG
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DY268 is a research compound that functions as a potent farnesoid X receptor (FXR) antagonist used in biochemical and cell-based studies of FXR signaling and drug-induced liver injury. Analytical data and supplier listings report defined composition, high purity, and suitability for in vitro assays.
- Potent farnesoid X receptor antagonist (IC50 = 7.5 nM).
- Inhibits FXR transactivation in cell-based assays (IC50 = 468 nM).
- High reported purity (~99.3% by HPLC).
- Defined chemical formula C30H32N4O5S and molecular weight 560.66 Da.
- Soluble in DMSO for in vitro use.
- Available in small research quantities suitable for assay development.
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Medchemexpress LLC AZ10606120 dihydrochloride | 607378-18-7 | 99.9% | 495.48 | 100 MG
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AZ10606120 dihydrochloride is a selective, high-affinity antagonist for the P2X7 receptor (P2X7R) in human and rat, with an IC50 of approximately 10 nM. It shows minimal to no effect on other P2XR subtypes. This compound demonstrates anti-depressant properties and has been observed to reduce tumor growth.
- Selective, high-affinity antagonist for P2X7 receptor
- Minimal cross-reactivity with other P2XR subtypes
- Exhibits anti-depressant effects
- Reduces tumor growth in various models
- Depletes tumor cells in patient-derived glioblastoma samples
- Increases lactate dehydrogenase levels in human glioblastoma cultures
- Reduces proliferation, cell migration, and invasion in PDAC cell lines
- Reverses streptozotocin-induced VEGF and IL-6 expression in rat retinae
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Medchemexpress LLC Nitrofurantoin | 67-20-9 | MFCD00003224 | 99.7% | C8H6N4O5 | 1 ML
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Nitrofurantoin is a potent, orally active, broad-spectrum beta-lactamase antimicrobial agent. It functions as an antibiotic, making it suitable for research into urinary tract infections (UTIs), including cystitis and kidney infections.
- Potent broad-spectrum antimicrobial agent
- Antibiotic for urinary tract infection research
- Purity of 99.7%
- Soluble in DMSO (100 mg/mL)
- Light yellow to yellow solid appearance
- For research use only
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