Furans
Medchemexpress LLC BMS-986202 | 1771691-34-9 | 99.3% | C22H18D3FN6O3 | 10MG
BMS-986202 is a deuterated, orally active TYK2 inhibitor used in research to interrogate TYK2-mediated inflammatory signaling. It binds the TYK2 JH2 pseudokinase domain with very high potency (reported IC50 = 0.19 nM; Ki = 0.02 nM) and has been characterized in preclinical and clinical studies. Supplied as a high-purity research compound for biochemical and cell-based assays; not for human therapeutic use.
- Deuterated analogue designed for improved metabolic stability.
- High potency against TYK2 JH2, enabling sensitive biochemical assays.
- Marked selectivity over related kinases, reducing off-target effects.
- High purity (99.3%), supporting reproducible experimental results.
- Available in multiple solid and solution pack sizes for assay flexibility.
- Suitable for both in vitro and in vivo research applications.
- Intended for research use only; not for clinical or human therapeutic use.
Medchemexpress LLC Cct365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 | C18H18ClNO4S3 | 10MG
CCT365623 hydrochloride is the hydrochloride salt of a small-molecule lysyl oxidase (LOX) inhibitor used for preclinical research. It suppresses EGFR (pY1068) and AKT phosphorylation, is orally active in models, and has demonstrated favorable tolerability and pharmacokinetic properties.
- Orally active LOX inhibitor (IC50 = 0.89 μM).
- High purity (98.1%) suitable for biological studies.
- Available in small research pack sizes for in vitro and in vivo use.
- Soluble in DMSO (250 mg/mL); in vivo formulation protocols provided.
- Storage guidance included for solid and solution stability.
- Intended for research use only; not for human administration.
Medchemexpress LLC Lobenzarit | 63329-53-3 | MFCD00866065 | 99.4% | 291.69 | C14H10ClNO4 | 10MG
Lobenzarit is a small-molecule immunomodulator provided for laboratory research. It exhibits antioxidative activity and is intended for use in in vitro and preclinical studies; consult the supplier COA and SDS for handling, storage, and purity information.
- Immunomodulatory activity
- Antioxidative properties
- High purity: 99.4%
- Available in small mass quantities suitable for research
- Documentation provided: COA and SDS
- Intended for in vitro and preclinical applications
Medchemexpress LLC 2,4-imidazolidinedione, 1-amino-, hydrochloride (1:1) | 2827-56-7 | MFCD02181047 | 98.0% | 151.55 | C3H6ClN3O2 | 10g
1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
Medchemexpress LLC Cobomarsen | 1848257-52-2 | C148H177N52O77P13S13 | 10MG
Cobomarsen is a locked nucleic acid (LNA)-based antisense oligonucleotide that selectively inhibits microRNA-155 (miR-155). Supplied as a solid (white to off-white) research reagent, it is used in preclinical studies to modulate miR-155-driven signaling and investigate oncology models by affecting pathways such as JAK/STAT, MAPK/ERK, and PI3K/AKT. The sodium salt form offers improved stability; the compound is highly water soluble and requires sealed, moisture-free storage.
- Selective inhibition of miR-155 and related survival pathways
- Suitable for preclinical oncology and lymphoma research
- High aqueous solubility; may require ultrasonication
- Improved stability as the sodium salt compared with the free acid
- Store sealed and protected from moisture; long-term storage in solution at -80 °C
Medchemexpress LLC Etiocholanolone (5β-Androsterone) | 53-42-9 | 99.5% | 290.44 | 50 MG
Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity. Etiocholanolone is a less potent neurosteroid positive allosteric modulator (PAM) of the GABAA receptor than its enantiomer form.
- It is the excreted metabolite of testosterone.
- It has anticonvulsant activity.
- It is a less potent neurosteroid positive allosteric modulator of the GABAA receptor than its enantiomer form.
- It exhibits ED50 values of 57.6 and 109.1 mg/kg in the 6-Hz and PTZ tests, respectively.
Medchemexpress LLC Nitrofurantoin | 67-20-9 | 238.16 | 5 G
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. It acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
- Potent and orally active broad-spectrum beta-lactamase antimicrobial agent
- Acts as an antibiotic
- Used for the study of urinary tract infections (UTIs), including cystitis and kidney infections
- Targets bacteria
- Melting/freezing point of 268°C
Medchemexpress LLC Opiranserin hydrochloride | 1440796-75-7 | 99.6% | 430.97 | 10 MG
Opiranserin hydrochloride is a non-opioid and non-NSAID analgesic candidate. It functions as a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A). It also exhibits antagonistic activity on rP2X3. Opiranserin hydrochloride is being developed as an injectable agent for the treatment of postoperative pain.
- Functions as a dual antagonist of GlyT2 and 5HT2A.
- Exhibits antagonistic activity on rP2X3.
- Effectively reduces mechanical allodynia and pain-related behaviors.
- Involved in clinical trials for postoperative pain, healthy, and radiculopathy/sciatica.
Medchemexpress LLC Pyribencarb | 799247-52-2 | MFCD22200855 | ≥95.0% | 361.83 | C18H20ClN3O3 | 50 MG
Pyribencarb is a benzylcarbamate-class fungicide supplied as a research-grade standard. It acts as a Qo inhibitor of cytochrome b (complex III) in the mitochondrial electron transport chain and shows activity against a broad range of plant pathogenic fungi. The compound is intended for analytical, in vitro antifungal, and mode-of-action studies.
- Inhibits cytochrome b (complex III) via the Qo site, enabling mechanism-of-action research.
- Active against common plant pathogens such as Botrytis cinerea and Sclerotinia sclerotiorum.
- Provided as a solid reference material suitable for analytical assays and standards.
- Storage stability as powder at low temperatures supports long-term archiving.
- Applicable to in vitro antifungal testing and comparative potency studies.
Medchemexpress LLC SID7970631 | 868224-75-3 | 98.3% | 50 MG
SID7970631, an isoquinolinone analog, is a potent and selective submicromolar SF-1 inhibitor with an IC50 of 255 nM. It is used for cancer research.
- Potent and selective submicromolar SF-1 inhibitor (IC50 of 255 nM)
- Used for cancer research
- Exhibits a half-maximal cytotoxic effect in CHO-K1 cells
- Dose-dependently inhibits luciferase expression in the SF-1 assay
- Shows cytotoxic effects on H295R/TR SF-1 cells and SW-13 cells
- Molecular weight is 452.46 with the formula C24H24N2O7
- Appears as a white to off-white solid
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC LY-3381916 (IDO1-IN-5) | 2166616-75-5 | 99.9% | 396.45 | 1 ML
LY-3381916 (IDO1-IN-5) is a potent, selective, and brain-penetrated inhibitor of IDO1 activity. It binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. This product is for research use only and not sold to patients.
- Potent, selective, and brain-penetrated inhibitor of IDO1 activity.
- Binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
- No obvious agonism of aryl hydrocarbon receptor (AHR) up to 100 μM.
eMolecules 959236-79-4 | 8-Iodoquinazoline-2,4(1H,3H)-dione | MFCD09954831 | 100mg
Ambeed | 8-Iodoquinazoline-2,4(1H,3H)-dione | 100mg | 552627626 | A185660 | 959236-79-4 | MFCD09954831 | 288.044 | C8H5IN2O2
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Medchemexpress LLC 1-aminohydantoin hydrochloride | 2827-56-7 | MFCD02181047 | ≥98.0% | 151.55 | C3H6ClN3O2 | 50mg
1-Aminohydantoin hydrochloride (Standard) is the analytical standard of 1-Aminohydantoin hydrochloride (HY-Y0469) This product is intended for research and analytical applications 1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
Medchemexpress LLC 1-Aminohydantoin | 6301-02-6 | 115.09 | 100 MG
1-Aminohydantoin is a Furagin derivative with a molecular weight of 115.09 and a chemical formula of C3H5N3O2. Its CAS number is 6301-02-6. This product is intended for research use only and is not for human use.
- For research use only, not intended for human use.
- Molecular weight of 115.09.
- Chemical formula of C3H5N3O2.
- CAS number 6301-02-6.
- Ships at room temperature in continental US.
- Store under recommended conditions in the Certificate of Analysis.
Medchemexpress LLC 2-isopropylphenyl N-(2-naphthalen-2-yl)ethyl carbamate | 1354359-53-7 | MFCD20926355 | 99.5% | 333.42 g/mol | C22H23NO2 | 10 MG
JW480 is a potent, selective carbamate inhibitor of the serine hydrolase KIAA1363 (AADACL1). It is used as a research reagent to probe KIAA1363 function in lipid metabolism and cancer-relevant cellular pathways, and is supplied with characterization data appropriate for biochemical and cellular studies.
- Selective inhibitor of the serine hydrolase KIAA1363.
- Suitable for biochemical and cell-based assays.
- Carbamate-based small-molecule structure for target engagement studies.
- High purity and defined molecular properties for reproducible results.
- Provided with catalog and registry identifiers for traceability.