Furans
Medchemexpress LLC YH-306 | 1373764-75-0 | 98.3% | 5 MG
YH-306 is a small-molecule antitumor agent that inhibits focal adhesion kinase (FAK) signaling and reduces cancer cell migration, invasion, and metastasis in preclinical studies.
- Inhibits focal adhesion kinase (FAK) signaling and related pathways.
- Reduces expression of MMP2 and MMP9.
- Inhibits Arp2/3-mediated actin polymerization.
- Molecular formula: C19H18N2O2.
- Molecular weight: 306.36 g/mol.
- Purity: 98.3%.
- Appearance: light yellow to light brown solid.
- Storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
Apexbio Technology LLC 5-hydroxymethyl-2-furaldehyde 67-47-0 20mg
5-hydroxymethyl-2-furaldehyde (67-47-0) is a small-molecule inhibitor targeting yeast metabolic pathways It is designed to suppress yeast growth and fermentation thereby modulating microbial metabolism 5-hydroxymethyl-2-furaldehyde exerts its biological activity primarily through inhibition of yeast metabolic processes In cell-based studies 5-hydroxymethyl-2-furaldehyde demonstrates inhibitory activity with an IC50 value of approximately 2 5 5 0 mM depending on yeast strain and experimental conditions Based on these pharmacological properties 5-hydroxymethyl-2-furaldehyde holds research potential in studies of yeast biology fermentation inhibition mechanisms and microbial metabolism
![Medchemexpress LLC 4-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl]-2-methyl-1(2H)-isoquinolinone | 1706738-98-8 | >98.0% | C21H21NO4S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259395.png-250.jpg)
Medchemexpress LLC 4-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl]-2-methyl-1(2H)-isoquinolinone | 1706738-98-8 | >98.0% | C21H21NO4S | 10MG
Trotabresib is an oral, potent, reversible small-molecule inhibitor of bromodomain and extra-terminal (BET) proteins. It is used in preclinical and clinical oncology research for advanced solid tumors and glioma and is supplied as a research-grade solid for translational studies.
- Oral, reversible BET inhibitor suitable for epigenetic research.
- Demonstrates antitumor activity in cell lines and xenograft models.
- High purity (typically >98%) for reliable experimental results.
- Solid powder form, soluble in common organic solvents such as DMSO.
- Applicable to preclinical and clinical translational studies in oncology.
Medchemexpress LLC Camelliaside A | 135095-52-2 | 5 MG
Camelliaside A is a phytochemical that acts as a HER2 ligand. It has been shown to lack antifungal activity against *Rhizoctonia solani* and is applicable to breast cancer-related research.
- Phytochemical and HER2 ligand
- Shows no inhibitory effect on mycelial growth of *Rhizoctonia solani*
- Applicable to breast cancer-related research
- Off-white to light yellow solid appearance
- Purity of 99.65%
- Store at 4°C, protect from light. In solvent: -80°C for 6 months; -20°C for 1 month (protect from light).
- Soluble in DMSO (100 mg/mL)
Medchemexpress LLC Linperlisib | 1702816-75-8 | MFCD31544346 | 98.9% | 588.69 g·mol⁻¹ | C28H37FN6O5S | 25 MG
Linperlisib is a potent, orally bioavailable, and selective inhibitor of phosphoinositide 3-kinase delta (PI3Kδ) developed for research applications. It demonstrates an IC50 of approximately 6.4 nM against PI3Kδ and is supplied as a high-purity solid suitable for in vitro and preclinical studies.
- Potent, selective inhibitor of PI3Kδ (IC50 ≈ 6.4 nM).
- Orally bioavailable profile useful for in vivo studies.
- Supplied as a high-purity solid (≈98.9%).
- Suitable for in vitro and preclinical research applications.
- Available in multiple small-scale quantities for laboratory use.
- Recommended storage at low temperatures to preserve stability.
Medchemexpress LLC Tovinontrine (IMR-687) | 2062661-53-2 | 99.8% | 394.47 | 1 ML
Tovinontrine (IMR-687) | 2062661-53-2 | 99.8% | 394.47 | 1 ML
Medchemexpress LLC 2-isopropylphenyl (2-(naphthalen-2-yl)ethyl)carbamate | 1354359-53-7 | MFCD20926355 | 99.5% | 333.42 g/mol | C22H23NO2 | 50 MG
JW480 is a potent, selective small-molecule inhibitor of the serine hydrolase KIAA1363 (AADACL1) used in biochemical and cell-based research to probe enzyme function and related pathways. This compound is supplied for research use only.
- Potent, selective inhibitor of KIAA1363.
- Intended for research use only.
- High purity: 99.54%.
- Chemical formula: C22H23NO2.
- Molecular weight: 333.42 g/mol.
- CAS number: 1354359-53-7.
- Supplied as a 50 mg quantity.
Medchemexpress LLC ATH686 | 853299-52-2 | 99.54% | 515.53 | 5 MG
ATH686 is a potent, selective, and ATP-competitive FLT3 inhibitor that targets mutant FLT3 protein kinase activity. It inhibits the proliferation of cells harboring FLT3 mutants by inducing apoptosis and cell cycle inhibition, also exhibiting antileukemic effects.
- Potently inhibits cell proliferation (IC50 around 0.001 μM) in FLT3-ITD-Ba/F3 cells and D835Y-Ba/F3 cells
- Induces apoptosis
- Inhibits autophosphorylation of mutant FLT3
- Exhibits antileukemic effects
Medchemexpress LLC Batabulin sodium | 195533-98-3 | MFCD22380600 | 99.8% | C13H6F6NNaO3S | 10MG
Batabulin sodium is the sodium salt of batabulin, a tubulin-targeting antitumor research compound that covalently binds a subset of β-tubulin isotypes and disrupts microtubule dynamics, inducing apoptosis in cell models. It is supplied as a high-purity reagent for biochemical and cellular studies of microtubules, tubulin covalent modification, and related pharmacology.
- Covalently binds a subset of β-tubulin isotypes and disrupts microtubule dynamics.
- Used to study apoptosis, cell division, and tubulin-targeting pharmacology.
- Supplied as a high-purity research reagent (99.8%).
- Provided in multiple pack sizes and concentration formats for lab use.
- Sodium salt form suitable for biochemical and cell-based assays.
Medchemexpress LLC Khasianine | 32449-98-2 | 5 MG
Khasianine is a steroidal glycoalkaloid obtained from black nightshade (Solanum Nigrum L.). It displays antitumor activity.
- Derived from black nightshade (Solanum Nigrum L.)
- Exhibits antitumor activity
- Steroidal glycoalkaloid
Medchemexpress LLC PF-06456384 trihydrochloride | 1834610-75-1 | 99.4% | 829.18 g/mol | C35H35Cl3F3N7O3S2 | 100 MG
PF-06456384 trihydrochloride is a potent, selective small-molecule inhibitor of the voltage-gated sodium channel NaV1.7 for laboratory research use. Provided as the trihydrochloride salt, it appears as a white to off-white solid with high listed purity and is used in preclinical pain-model studies. Available in solid and solution formats for flexible assay setup.
- Potent NaV1.7 inhibition (IC50 = 0.01 nM), enabling high-sensitivity pharmacology studies.
- Trihydrochloride salt form for improved solubility and handling.
- High listed purity for reproducible experimental results.
- Available in multiple pack sizes and as a 10 mM DMSO solution for assay flexibility.
- Intended for laboratory research use only; not for human or veterinary use.
Medchemexpress LLC TCS PrP Inhibitor 13 25mg | 34320-83-7 | 25MG
TCS PrP Inhibitor 13 an antiprion agent is a cellular prion protein (PrPC) inhibitor TCS PrP Inhibitor 13 as a protease-resistant form of prion protein (PrP-res) accumulation inhibitor shows an IC50 value of 3 nM in both ScN2a and F3 cell lines TCS PrP Inhibitor 13 induces Schwannoma cells apoptosis[1