Furans
Medchemexpress LLC BMS-911172 10mg | 1644248-18-9 | 339.34 | C16H19F2N3O3 | 10 MG
BMS-911172 is a small-molecule inhibitor of adaptor-associated kinase 1 (AAK1) provided for laboratory research. It has reported nanomolar potency and is offered at high purity for biochemical and cellular studies.
- Selective AAK1 inhibition with nanomolar potency (IC50 ≈ 35 nM).
- High reported purity (≈99.5%).
- Molecular weight 339.34; formula C16H19F2N3O3.
- Soluble in DMSO; solution format available.
- Available in small-scale quantities suitable for research workflows.
- For research use only; not for clinical or human use.
Medchemexpress LLC BMS-911172 5mg | 1644248-18-9 | 5 MG
BMS-911172 is a small-molecule inhibitor of adaptor protein 2-associated kinase 1 (AAK1) supplied as a solid for laboratory research. It is brain-penetrant and reported to have low-nanomolar potency in biochemical and cellular assays (reported IC50 values ≈12-35 nM). For research use only.
- Potent AAK1 inhibitor with low-nanomolar activity.
- Brain-penetrant small molecule suitable for CNS-targeted studies.
- High purity (~99.5%) solid form for analytical and biological work.
- Supplied in a small quantity suitable for pilot or mechanistic studies.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC PF-06456384 trihydrochloride | 1834610-75-1 | 99.4% | 829.18 g/mol | C35H35Cl3F3N7O3S2 | 100 MG
PF-06456384 trihydrochloride is a potent, selective small-molecule inhibitor of the voltage-gated sodium channel NaV1.7 for laboratory research use. Provided as the trihydrochloride salt, it appears as a white to off-white solid with high listed purity and is used in preclinical pain-model studies. Available in solid and solution formats for flexible assay setup.
- Potent NaV1.7 inhibition (IC50 = 0.01 nM), enabling high-sensitivity pharmacology studies.
- Trihydrochloride salt form for improved solubility and handling.
- High listed purity for reproducible experimental results.
- Available in multiple pack sizes and as a 10 mM DMSO solution for assay flexibility.
- Intended for laboratory research use only; not for human or veterinary use.
Medchemexpress LLC C-021 | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 5 MG
C-021 is a small-molecule antagonist of the CC chemokine receptor 4 (CCR4) used for research into GPCR signaling and immunology. It inhibits CCR4-mediated chemotaxis in human and mouse systems and is supplied as a solid for laboratory studies.
- Target CCR4.
- Molecular formula C27H41N5O2.
- Molecular weight 467.65 g/mol.
- Purity 99.95%.
- Appearance solid, off-white to light yellow.
- Storage powder: -20°C (up to 3 years); in solvent: -80°C (short-term).
- Supplied in small research quantities.
Medchemexpress LLC Trovafloxacin mesylate | 147059-75-4 | MFCD00913361 | 99.6% | 512.46 g·mol⁻¹ | C21H19F3N4O6S | 50 MG
Trovafloxacin mesylate is the methanesulfonate (mesylate) salt of trovafloxacin, a broad-spectrum fluoroquinolone antibiotic supplied for research use. It inhibits bacterial DNA gyrase and topoisomerase IV and has been reported to block pannexin 1 (PANX1) channels in cellular assays.
- Broad-spectrum fluoroquinolone antibiotic and research reagent.
- Inhibits DNA gyrase and topoisomerase IV.
- Reported PANX1 inhibitor in cellular assays.
- Molecular formula C21H19F3N4O6S; molecular weight 512.46 g·mol⁻¹.
- Salt form: mesylate (methanesulfonate).
- Packaged as 50 mg for research use.
- CAS number 147059-75-4.
Medchemexpress LLC 3-(4-nitrophenyl)-1-phenyl-2-pyrazolin-5-one | 34320-83-7 | 99.7% | 281.27 g/mol | C15H11N3O3 | 5 MG
TCS PrP Inhibitor 13 is a small-molecule antiprion compound that inhibits accumulation of protease-resistant prion protein in cellular assays. It has been reported to show potent cellular activity and is used as a research reagent for studies of prion biology and for screening antiprion compounds.
- Potent antiprion activity with reported cellular IC50 ~3 nM.
- High chemical purity (99.7%).
- Chemical formula C15H11N3O3 and molecular weight 281.27 g/mol.
- Suitable for prion biology research and antiprion compound screening.
- Provided in milligram quantities for laboratory studies.
Medchemexpress LLC TCS PrP Inhibitor 13 25mg | 34320-83-7 | 25MG
TCS PrP Inhibitor 13 an antiprion agent is a cellular prion protein (PrPC) inhibitor TCS PrP Inhibitor 13 as a protease-resistant form of prion protein (PrP-res) accumulation inhibitor shows an IC50 value of 3 nM in both ScN2a and F3 cell lines TCS PrP Inhibitor 13 induces Schwannoma cells apoptosis[1
Medchemexpress LLC Pf-06456384 trihydrochloride | 1834610-75-1 | 99.4% | 829.18 g/mol | C35H35Cl3F3N7O3S2 | 5 MG
PF-06456384 trihydrochloride is a research-grade small-molecule trihydrochloride salt and a highly potent, selective NaV1.7 inhibitor (reported IC50 = 0.01 nM) provided for preclinical pharmacology and pain-model studies.
- High potency and selectivity toward NaV1.7 for target validation and pharmacology studies.
- Trihydrochloride salt form improves compound handling and solubility for assays.
- High purity (reported ~99.38%) suitable for research applications.
- Molecular weight 829.18 g/mol; white to off-white solid.
- Supplied in small research quantities for assay development and in vivo pilot studies.
Research Products International Corp Nitrofurantoin, 1 Gram
Nitrofurantoin works by inhibiting bacterial enzymes involved in the metabolism of certain compounds, leading to the disruption of bacterial DNA, RNA, and protein synthesis.
Researchers may use nitrofurantoin as a selective agent by incorporating it into culture media to promote the growth of cells or organisms that have been genetically engineered to express resistance to this antibiotic. It may have applications in microbiology and cell culture experiments, particularly in the context of antibiotic selection.
WARNING! This product can expose you to Nitrofurantoin, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
![Medchemexpress LLC 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1h-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine | 873551-53-2 | 99.3% | 358.41 g·mol⁻¹ | C18H23FN6O | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1h-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine | 873551-53-2 | 99.3% | 358.41 g·mol⁻¹ | C18H23FN6O | 5 MG
FTIDC is an orally active, noncompetitive, selective allosteric antagonist of the metabotropic glutamate receptor 1 (mGluR1). It shows potent antagonistic activity and similar pharmacology across human, mouse, and rat recombinant receptors. Supplied for research use only, it is intended for in vitro and in vivo pharmacology and signaling studies.
- Selective allosteric mGluR1 antagonist
- Potent activity (IC50 5.8 nM for human mGluR1a)
- Cross-species activity (human, mouse, and rat)
- High purity (99.3%)
- Supplied as small solid quantities or 10 mM solution in DMSO
- Suitable for in vitro and in vivo pharmacology studies
Medchemexpress LLC Epoxiconazole | 133855-98-8 | 99.0% | 50 MG
Epoxiconazole (Standard) is an analytical reference standard of the fungicide epoxiconazole, intended for research and analytical applications such as qualitative and quantitative methods by HPLC, GC, and MS.
- Analytical standard for HPLC, GC, and MS methods.
- Used as a reference for qualitative and quantitative analyses.
- Molecular formula C17H13ClFN3O and molecular weight 329.76 g/mol.
- Available in small pack sizes suitable for laboratory reference use.
Medchemexpress LLC Camelliaside A | 135095-52-2 | MFCD28988581 | 99.7% | 756.66 | C33H40O20 | 10 MG
Camelliaside A is a flavonoid isolated from Camellia oleifera seed pomace and supplied as a high-purity research standard for in vitro and in vivo studies.
- Flavonoid compound with CAS number 135095-52-2.
- Molecular formula C33H40O20 and molecular weight 756.66.
- High purity: 99.65% (manufacturer reported).
- Soluble in DMSO (100 mg/mL); ultrasonic assistance recommended.
- Multiple in vivo formulations documented with ≥2.5 mg/mL solubility.
- Storage: product at 4°C protected from light; in solvent: -80°C (6 months) or -20°C (1 month).
- Intended for research use only.
Medchemexpress LLC PDE4B-IN-2 5mg | 915082-52-9 | 387.88 | C19H18ClN3O2S | 5 MG
An orally active, selective phosphodiesterase 4B (PDE4B) inhibitor with potent anti-inflammatory activity; shows an IC50 of 15 nM for PDE4B and 1.7 μM for PDE4D. Supplied as a white to off-white solid with high purity and provided with storage recommendations for long-term stability.
- Selective PDE4B inhibition (IC50 15 nM).
- Lower activity against PDE4D (IC50 1.7 μM), supporting selectivity.
- High purity research grade material for in vitro and in vivo studies.
- Stable solid form with defined storage conditions for extended shelf life.
- Demonstrated anti-inflammatory effects in cellular and mouse models.
Apexbio Technology LLC Menadiol Diacetate 573-20-6 200mg
Menadiol Diacetate (CAS 573-20-6) is a synthetic derivative of vitamin K investigated for its regulatory effects on cellular signaling pathways and enzyme activities In experimental studies Menadiol Diacetate has been shown to induce S phase arrest in the cell cycle leading to apoptotic cell death This compound is utilized in research focused on cancer and related diseases providing a tool for exploring mechanisms of cell proliferation and apoptosis in vitro
Apexbio Technology LLC PYR-41,10mg CAS# 418805-02-4
Ubiquitylation is catalyzed by the sequential action of ubiquitinactivating enzyme (E1), a ubiquitin-conjugating enzyme (E2) and a ubiquitin protein ligase (E3). Ubiquitylation is essential to numerous cellular and developmental processes, including protein quality control, growth, apoptosis, antigen presentation, DNA repair, and signal transduction. PYR-41, 4[4-(5-nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester, is a selective inhibitor of Ubiquitin-Activating Enzyme (E1).In vitro: In addition to blocking ubiquitylation, PYR-41 was found to increase total sumoylation in cells. PYR-41 could attenuate cytokine-mediated nuclear factor-KBactivation. This correlated with inhibition of nonproteasomal ubiquitylation of TRAF6, which is important to IKBkinase activation. Other sizes are also available. Please inqury us for quote.