Furans
Sigma Aldrich 2-Furoic acid
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 1-Aminopyrene
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 3-(4-Piperidinyl)propanamide hydrochloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Furazolidone, G-Biosciences
Molecular Weight (g/mol): 225.16 g/mol
Medchemexpress LLC Sincalide (ammonium) | 70706-98-8 | 99.2% | 1160.30 | 10 MG
Sincalide ammonium is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. It is a major bioactive segment of CCK that retains most of its biological activities. CCK-8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders, increasing bile secretion, causing gallbladder contraction, and relaxing the sphincter of Oddi for bile drainage into the duodenum.
- Significant inhibitory effect on myocardial fibrosis in noninfarcted areas
- Positive role in fighting inflammation, apoptosis, and collagen deposition
- Protects H9c2 cardiomyoblasts from Ang II‐induced apoptosis
- Alleviates fibrosis in noninfarcted regions
- Delays left ventricular remodeling and the progress of heart failure in a MI rat model
Apexbio Technology LLC Dantrolene (sodium hemiheptahydrate) 24868-20-0 200mg
Dantrolene sodium hemiheptahydrate (CAS 24868-20-0) is an orally active noncompetitive inhibitor of glutathione reductase demonstrating inhibitory activity with a Ki of approximately 111 6 M and an IC50 of around 52 3 M In addition dantrolene inhibits ryanodine receptor calcium channels RyR1 and RyR3 thereby reducing intracellular calcium release This compound is utilized in studies investigating the dysregulation of calcium homeostasis such as those related to stroke ischemia-reperfusion injury and neurodegenerative disorders It is also explored in the contexts of muscle spasticity malignant hyperthermia analgesia anti-inflammatory responses and detoxification
Sigma Aldrich Fine Chemicals Biosciences Methyl 2-furoate >=98%, FG | 611-13-2 | MFCD00003236 | 5KG
Methyl 2-furoate >=98%, FG | Purity: >=98% | Mol Wt: 126.11 | 611-13-2 | MFCD00003236 | 5KG
Medchemexpress LLC Paederosidic acid | 18842-98-3 | MFCD28124366 | 5 MG
Paederosidic acid is isolated from *P. scandens* and exhibits anticancer and anti-inflammation activities. It inhibits lung cancer cells by inducing mitochondria-mediated apoptosis.
- Isolated from *Paederia scandens*
- Exhibits anticancer and anti-inflammation activities
- Inhibits lung cancer cells by inducing mitochondria-mediated apoptosis
- Molecular weight: 464.44
- Formula: C18H24O12S
- Appearance: Solid
- Color: White to light yellow
- Purity: 99.90%
- Relative density: 1.67 g/cm³
- Stable under recommended storage conditions
- Soluble in DMSO: 100 mg/mL (215.31 mM)
![Medchemexpress LLC 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-... | 873551-53-2 | 99.3% | 358.41 g/mol | C18H23FN6O | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000214055.png-250.jpg)
Medchemexpress LLC 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-... | 873551-53-2 | 99.3% | 358.41 g/mol | C18H23FN6O | 10 MG
FTIDC is a selective, noncompetitive allosteric antagonist of metabotropic glutamate receptor 1 (mGluR1) intended for research use. It is orally active and demonstrates potent antagonism against recombinant mGluR1, supporting pharmacology and neuroscience studies.
- Potent mGluR1 antagonism (IC50 5.8 nM for human mGluR1a).
- Selective noncompetitive allosteric mechanism.
- High chemical purity suitable for research applications.
- Defined physicochemical properties: C18H23FN6O; MW 358.41 g/mol; CAS 873551-53-2.
- Supplied in small-scale quantities appropriate for laboratory experiments.
Medchemexpress LLC SEW2871 | 256414-75-2 | 99.9% | 440.36 | 10 MG
SEW2871 is an orally active, potent, highly selective S1P1 (sphingosine-1-phosphate type 1 receptor) agonist, with an EC50 of 13.8 nM. It activates ERK, Akt, and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte numbers in blood and can be used for the research of diabetes, Alzheimer's disease, liver fibrosis, and inflammatory responses.
- Orally active, potent, highly selective S1P1 agonist.
- Activates ERK, Akt, and Rac signaling pathways.
- Induces S1P1 internalization and recycling.
- Reduces lymphocyte numbers in blood.
- Can be used for research of diabetes, Alzheimer's disease, liver fibrosis, and inflammatory responses.
Medchemexpress LLC Cct365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 | C18H18ClNO4S3 | 10MG
CCT365623 hydrochloride is the hydrochloride salt of a small-molecule lysyl oxidase (LOX) inhibitor used for preclinical research. It suppresses EGFR (pY1068) and AKT phosphorylation, is orally active in models, and has demonstrated favorable tolerability and pharmacokinetic properties.
- Orally active LOX inhibitor (IC50 = 0.89 μM).
- High purity (98.1%) suitable for biological studies.
- Available in small research pack sizes for in vitro and in vivo use.
- Soluble in DMSO (250 mg/mL); in vivo formulation protocols provided.
- Storage guidance included for solid and solution stability.
- Intended for research use only; not for human administration.
Medchemexpress LLC PF-06456384 trihydrochloride | 1834610-75-1 | ≥98.0% | 829.18 g·mol⁻¹ | C35H32F3N7O3S2 · 3HCl | 25 MG
The trihydrochloride salt is a small-molecule research compound described as a highly potent and selective inhibitor of the NaV1.7 voltage-gated sodium channel; it has reported sub-nanomolar activity and is used in preclinical pain model research.
- Highly potent and selective NaV1.7 inhibition (reported IC50 ≈ 0.01 nM).
- Used in preclinical pain models, including the formalin test.
- Supplied as a trihydrochloride salt in white to beige powder form.
- High purity (≥98% by HPLC reported by distributors).
- Solubility: readily soluble in DMSO (~125 mg/mL); limited aqueous solubility (~2 mg/mL reported).
Medchemexpress LLC Evixapodlin | 2374856-75-2 | 98.1% | C34H36Cl2N8O4 | 10MG
Evixapodlin is an orally bioavailable small-molecule inhibitor of programmed death-ligand 1 (PD-L1) used in research to modulate PD-1/PD-L1 protein-protein interactions. It has demonstrated potent activity in preclinical assays and has been evaluated in early clinical studies for advanced solid tumors.
- Chemical name: Evixapodlin.
- CAS number: 2374856-75-2.
- Molecular formula: C34H36Cl2N8O4.
- Molecular weight: 691.61.
- Reported IC50: 0.213 nM (PD-1/PD-L1 protein-protein interaction).
- Purity: 98.1% (HPLC).
- Physical form: powder for research use.
- Typical use: reagent for PD-1/PD-L1 pathway and oncology research.
Medchemexpress LLC CK2 inhibitor 2 | 2641079-92-5 | 98.5% | C21H17ClN4O2 | 10MG
CK2 inhibitor 2 is a potent, selective, orally active small-molecule inhibitor of casein kinase 2 (CK2) with sub-nanomolar enzymatic potency and documented cellular activity. Supplied as a solid for research use, it includes solubility data for DMSO and recommended storage conditions for powder and solutions.
- Potent CK2 inhibition (IC50 0.66 nM) for biochemical assays.
- Selectable kinase profile with measurable activity against Clk2.
- Cellular activity in multiple cancer cell lines at low micromolar concentrations.
- High purity suitable for biochemical and cell-based studies (98.5%).
- Documented solubility in DMSO and example in vivo formulation options.
- Defined storage recommendations for powder and solvent preparations.
Medchemexpress LLC Trovafloxacin (mesylate) | 147059-75-4 | MFCD00913361 | 99.6% | 512.46 g·mol⁻¹ | C21H19F3N4O6S | 100 MG
Trovafloxacin mesylate is the methanesulfonate (mesylate) salt of trovafloxacin, a fluoroquinolone antibiotic used as a research tool compound and analytical reference in microbiological and biochemical studies.
- Fluoroquinolone antibiotic salt suitable for research and analytical applications.
- Broad-spectrum activity against Gram-positive, Gram-negative, and anaerobic bacteria.
- Molecular formula C21H19F3N4O6S and molecular weight 512.46 g·mol⁻¹.
- CAS number 147059-75-4 for precise identification.
- Soluble in DMSO; commonly supplied as a dry powder for laboratory use.