Indoles and derivatives
Sigma Aldrich 1-BUTYLDIETHYLSILANE POLYMER-BOUND 50-100 MESH 1.25 MMOL SI/G
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
![9-Phenyl-3,6-bis[4-(1-phenylbenzimidazol-2-yl)phenyl]carbazole 98.0+%, TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-1258780-50-5.jpg-250.jpg)
9-Phenyl-3,6-bis[4-(1-phenylbenzimidazol-2-yl)phenyl]carbazole 98.0+%, TCI America™
CAS: 1258780-50-5 Molecular Formula: C56H37N5 Molecular Weight (g/mol): 779.947 InChI Key: CWUOZRFIMAVZLO-UHFFFAOYSA-N PubChem CID: 101525816 IUPAC Name: 9-phenyl-3,6-bis[4-(1-phenylbenzimidazol-2-yl)phenyl]carbazole SMILES: C1=CC=C(C=C1)N2C3=C(C=C(C=C3)C4=CC=C(C=C4)C5=NC6=CC=CC=C6N5C7=CC=CC=C7)C8=C2C=CC(=C8)C9=CC=C(C=C9)C1=NC2=CC=CC=C2N1C1=CC=CC=C1
Medchemexpress LLC Oncrasin-1 | 75629-57-1 | 98.16% | 269.73 | 50 MG
Oncrasin-1 | 75629-57-1 | 98.16% | 269.73 | 50 MG
Medchemexpress LLC 5-Bromoindole | 10075-50-0 | 99.97% | 196.05 | 1 ML
5-Bromoindole is an antibacterial agent with a MIC of 200 μg/mL. It inhibits biofilm and curli formation, and reduces swarming and swimming motility. This compound can be used for the research of enterohemorrhagic escherichia coli o157:h7 infection.
- Antibacterial agent
- Inhibits biofilm and curli formation
- Reduces swarming and swimming motility
- Useful for enterohemorrhagic escherichia coli o157:h7 infection research
Medchemexpress LLC Sodium carboxyl methylstarch | 9063-38-1 | C2H4O3·xNa·x | 50 G
Sodium carboxyl methylstarch is the sodium salt of carboxyl methylstarch, a modified starch used as a biochemical reagent and pharmaceutical excipient. It is supplied as a white to off-white solid intended for laboratory research use only and commonly formulated as a disintegrant or viscosity modifier in life science applications.
- White to off-white solid appearance.
- Sodium salt of carboxyl methylstarch.
- Used as a biochemical reagent and pharmaceutical excipient.
- Common applications include tablet disintegration and formulation testing.
- Available in laboratory pack sizes (25 g, 50 g, 100 g).
- CAS number 9063-38-1; for research use only.
Medchemexpress LLC 4-Hydroxyindole (Standard) | 2380-94-1 | 97% | 133.15 | 50 MG
4-Hydroxyindole (Standard) is the analytical standard of 4-Hydroxyindole, intended for research and analytical applications. It is a hydroxyindole that is 1H-indole substituted by a hydroxy group at position 4. This compound is an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers.
- Used as an analytical standard
- Reference standard supplied assay
- Commonly used in qualitative research experiments
- Commonly used in quantitative research experiments
- Commonly used in methodological research experiments
- Applicable in HPLC, GC, and MS
Medchemexpress LLC 1-(4-Chlorophenyl)piperazine | 38212-33-8 | 196.68 | 50 G
1-(4-Chlorophenyl)piperazine is a chemical intermediate used for the synthesis of D2R ligand. It is intended for research purposes only.
- Solid appearance
- White to light yellow color
- Soluble in DMSO (100 mg/mL)
Medchemexpress LLC Indole-3-carboxylic acid | 771-50-6 | 99.96% | 161.16 | 1 G
Indole-3-carboxylic acid is an orally active urinary indolic tryptophan metabolite. This compound mediates priming against Plectosphaerella cucumerina and enhances anti-colorectal cancer potency by inducing cell senescence. It is also applicable in liver disease research.
- High purity of 99.96%.
- Orally active urinary indolic tryptophan metabolite.
- Mediates priming against Plectosphaerella cucumerina.
- Enhances anti-colorectal cancer effects via cell senescence.
- Applicable in liver disease research.
- Available as a 10 mM * 1 mL solution in DMSO.
- Available in solid forms: 1 g, 5 g, 10 g, 25 g, 50 g, and > 100 g.
Medchemexpress LLC Fgin 1-27 | 142720-24-9 | 100.0% | 436.60 | C28H37FN2O | 50 MG
FGIN 1-27 is a small-molecule ligand for the translocator protein (TSPO/PBR) used in preclinical research to study mitochondrial benzodiazepine receptor function and neuropharmacology. It is supplied as a solid research chemical with a defined purity and storage recommendations suitable for laboratory assays.
- High purity for reproducible experimental results.
- Solid, off-white to light yellow material for easy handling.
- Storage recommendations support long-term stability at low temperatures.
- Available in small pack sizes for flexibility in dosing and experiments.
- Well-characterized chemical identifiers (CAS 142720-24-9) for unambiguous identification.
Medchemexpress LLC Phenazine-1-carboxylic acid | 2538-68-3 | 100.0% | 224.21 | 50 MG
Phenazine-1-carboxylic acid is an antifungal agent that also exhibits anticancer activity by inducing apoptosis in cancer cells through the regulation of ROS generation. It can upregulate the expression of IL-8 and ICAM-1 while inhibiting the release of RANTES and MCP-1, indicating potential immunomodulatory effects. It is valuable for research in anti-infection, anticancer, and immune response modulation.
- Antifungal agent
- Exhibits anticancer activity
- Induces apoptosis in cancer cells through ROS generation
- Upregulates IL-8 and ICAM-1 expression
- Inhibits release of RANTES and MCP-1
- Antineuroinflammatory activity
- Cytotoxicity against HCT-116 cells
- Inhibits proliferation in DU145 cells
- Significantly prevented V. anguillarum infection in zebrafish embryos
Medchemexpress LLC Indole-3-carboxylic acid | 771-50-6 | 100.0% | 161.16 | 1 ML
Indole-3-carboxylic acid is an orally active urinary indolic tryptophan metabolite. It mediates priming against *Plectosphaerella cucumerina* and enhances the anti-colorectal cancer potency of Doxorubicin by inducing cell senescence. It can also be utilized in liver disease research.
- Orally active urinary indolic tryptophan metabolite.
- Mediator of priming against *Plectosphaerella cucumerina*.
- Enhances anti-colorectal cancer potency of Doxorubicin through cell senescence induction.
- Applicable in liver disease research.
- For research use only.
Medchemexpress LLC Indomethacin (Standard) | 53-86-1 | MFCD00057095 | 99.81% | C₁₉H₁₆ClNO₄ | 50 MG
Indomethacin (Standard) is an analytical standard of Indomethacin, intended for research and analytical applications. It is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. This compound exhibits anticancer and anti-infective activities and can be utilized in research related to cancer, inflammation, and viral infections. It is commonly employed in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for Indomethacin
- Potent, orally active COX1/2 inhibitor
- Exhibits anticancer activity
- Possesses anti-infective activity
- Useful for cancer, inflammation, and viral infection research
- Suitable for HPLC, GC, and MS research experiments
Medchemexpress LLC Parp-2-in-1 | 2115698-83-2 | 99.6% | 465.40 g·mol⁻¹ | C21H19F4N5O3 | 50 MG
PARP-2-IN-1 is a potent, selective small-molecule inhibitor of poly(ADP-ribose) polymerase 2 (PARP-2) with a reported IC50 of 11.5 nM. Supplied as a high-purity powder, it is intended for biochemical and cellular research into DNA repair pathways and target validation studies.
- Potent PARP-2 inhibition with low nanomolar IC50.
- High chemical purity suitable for research use.
- Available in multiple preweighed sizes for experimental flexibility.
- Stable powder with defined cold-storage conditions.
- Suitable for biochemical assays and cellular studies of DNA damage response.
Medchemexpress LLC 1-Methyl-1H-indazole-3-carboxylic acid | 50890-83-0 | 176.17 | 50 G
1-Methyl-1H-indazole-3-carboxylic acid is a versatile biochemical reagent ideal for life science research. It functions as both a biological material and an organic compound, presenting as a white to off-white solid.
- Suitable for life science-related research
- Can be utilized as a biological material or organic compound
- Presents as a white to off-white solid
- Molecular weight of 176.17
- Soluble in DMSO at concentrations of 100 mg/mL or higher (567.63 mM)
- Storage recommendations: 3 years at room temperature; in solvent, 2 years at -80°C, or 1 year at -20°C