Lactams
eMolecules Thalidomide-5-(PEG4-acid) | Broadpharm |549.533 | C25H31N3O11 | 98.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 | 100mg | 713699648
Thalidomide-5-(PEG4-acid) | Broadpharm |549.533 | C25H31N3O11 | 98.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 | 100mg | 713699648
Medchemexpress LLC Thalidomide-pinacolborane | 2229725-98-6 | 97.0% | 384.19 g/mol | C19H21BN2O6 | 250 MG
Thalidomide-pinacolborane is a thalidomide analogue that incorporates a boronic pinacol ester (Bpin). It is used as a synthetic intermediate for cross-coupling chemistry and as an E3 ligase (cereblon) ligand in chemical biology and targeted protein degradation research.
- Contains a boronic pinacol ester suitable for Suzuki-Miyaura cross-coupling.
- Functions as an E3 ligase (cereblon) ligand for PROTAC and degradation studies.
- High purity appropriate for research applications.
- Available in research-scale quantities for assay development.
- Molecular formula C19H21BN2O6; molecular weight 384.19 g/mol.
Medchemexpress LLC Thalidomide-4-O-C6-NH2 hydrochloride | 2245697-88-3 | 98.5% | 409.86 | C19H24ClN3O5 | 5 MG
Thalidomide-4-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate supplied as the hydrochloride salt for research use. It is used as a building block in PROTAC dTAG-13, a degrader of FKBP12F36V and BET proteins, and is provided with supporting analytical data and handling documentation.
- Provided as the hydrochloride salt suitable for synthetic applications.
- High purity (98.5% by HPLC) with supporting analytical data.
- Analytical files include data sheet, COA, H NMR, and LCMS.
- Available in multiple pack sizes from milligrams to grams.
- Intended for research use only; not for human or therapeutic use.
Selleck Chemical LLC Brucine sulfate heptahydrate
Brucine is an alkaloid that acts as an antagonist at glycine receptors and paralyzes inhibitory neurons
Medchemexpress LLC Thalidomide-CH2NH2 hydrochloride | 444287-40-5 | MFCD32183715 | 98.0% | 323.73 g/mol | C14H14ClN3O4 | 10 MG
Thalidomide-CH2NH2 hydrochloride is a thalidomide analogue supplied as the hydrochloride salt for research use. It features a primary aminomethyl substituent that enables further functionalization and utility as a ligand-like scaffold in biochemical studies. The compound is provided as a high-purity solid suitable for synthetic chemistry and assay development.
- Contains a primary aminomethyl group for synthetic functionalization.
- Supplied as the hydrochloride salt for improved stability and handling.
- High purity suitable for research and assay development.
- Serves as a ligand scaffold for E3 ligase-related studies.
- Available in small-scale quantities for discovery workflows.
Medchemexpress LLC CD23/Fc epsilon RII 10ug
CD23/Fc epsilon RII Protein a low-affinity receptor for IgE and CR2/CD21 regulates IgE production and B cell differentiation On B cells it initiates IgE-dependent antigen uptake and presentation to T cells On macrophages IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding CD23/Fc epsilon RII Protein Mouse (HEK293 His) is the recombinant mouse-derived CD23/Fc epsilon RII protein expressed by HEK293 with N-His labeled tag
eMolecules 1950635-17-2 | Thalidomide-5-(C6-amine) | Broadpharm400.435 | C20H24N4O5 | 98.000 | NCCCCCCNC(=O)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 | 100mg | 713699636
Thalidomide-5-(C6-amine) | Broadpharm | 1950635-17-2400.435 | C20H24N4O5 | 98.000 | NCCCCCCNC(=O)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 | 100mg | 713699636
Medchemexpress LLC Thalidomide-4-O-C4-NH2 hydrochloride | 2376990-29-1 | MFCD32705123 | 99.4% | 381.81 | C17H20ClN3O5 | 5 MG
Thalidomide-4-O-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate supplied as the hydrochloride salt for use in PROTAC research. It couples a thalidomide-derived cereblon ligand to a four-carbon alkyl linker terminating in a primary amine, enabling conjugation to target-binding moieties. The material is intended for laboratory research use only.
- High purity (99.35%).
- Hydrochloride salt form for handling and stability.
- Molecular weight 381.81.
- Molecular formula C17H20ClN3O5.
- Available in small research quantities (5 mg and up).
- Intended for use in PROTAC design and cereblon-based degrader development.
Medchemexpress LLC Thalidomide 5-fluoride | 835616-61-0 | 100.0% | 276.22 | C13H9FN2O4 | 1 ML
Thalidomide 5-fluoride is a thalidomide-derived cereblon ligand used as a building block in targeted protein degradation (PROTAC) research and related chemical biology applications. It is supplied as both solid material and pre-formulated DMSO solutions to facilitate linker conjugation and assay use.
- Thalidomide-based cereblon ligand for CRBN recruitment.
- Cas number: 835616-61-0.
- Molecular formula C13H9FN2O4; molecular weight 276.22 g/mol.
- Purity reported at 99.96% (analytical).
- Available as 10 mM solution in DMSO (1 mL) and as solid in multiple package sizes.
- Storage: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
Medchemexpress LLC Thalidomide-5-NH2-C8-NH2 (TFA) | 2097509-49-2 | 514.49 g/mol | C23H29F3N4O6 | 10 MG
Thalidomide-5-NH2-C8-NH2 (TFA) is a thalidomide-derived intermediate provided as the trifluoroacetic acid salt for research use and compound synthesis. It is intended for laboratory applications only and should be handled using appropriate safety procedures; store sealed at -20°C away from moisture and light. In solvent, recommended storage is -80°C for up to 6 months or -20°C for up to 1 month.
- Salt form: trifluoroacetic acid (TFA) salt.
- Suitable for compound synthesis and as a building block.
- Molecular formula: C23H29F3N4O6.
- Molecular weight: 514.49 g/mol.
- Storage: sealed at -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or clinical use.
Cayman Chemical ThalIdomIde 5mg
An active enantiomer of (±)-thalidomide; enhances TPA-induced TNF-α production in HL-60 cells from 0.1-100 µM; preincubation of isolated RIR chicken donor blood reduces recipient chicken embryo splenomegaly in a model of graft versus host disease at 10 mg/ml; induces fetal malformations when administered to pregnant female rabbits at 150 mg/kg
Medchemexpress LLC 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | 26166-92-7 | MFCD30188073 | 98.4% | 337.13 | C13H9BrN2O4 | 100 MG
Thalidomide-5-Br is a brominated thalidomide derivative supplied for research use in studies of inflammation, tumor biology, and neurology. It is provided as a solid research reagent; consult lot-specific documentation for analytical details.
- Contains a bromodomain; used as a tool compound in biochemical and pharmacological research.
- Reported purity approximately 98% (see product documentation for lot-specific certificate of analysis).
- Solid, off-white to gray appearance suitable for analytical and synthetic applications.
- Storage recommendations: room temperature for shipping; in solution store at -80°C (2 years) or -20°C (1 year).
- Available in multiple pack sizes including 100 mg.
