Lactams
Medchemexpress LLC Thalidomide-PEG5-COOH | 2688100-28-7 | 95.9% | 522.50 | 25 MG
Thalidomide-PEG5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a thalidomide-based cereblon ligand and a linker utilized in PROTAC technology. This product is intended for research purposes only and not for medical, clinical diagnostic, or food use in humans or animals.
- Purity: 95.90%
- Appearance: Oil
- Color: Light yellow to brown
- Solubility: Soluble in DMSO at 50 mg/mL (95.69 mM)
Medchemexpress LLC Thalidomide 4-fluoride | 835616-60-9 | 99.8% | 276.22 | 10 G
Thalidomide 4-fluoride (Cereblon ligand 4) is a Cereblon-based ligand derived from Thalidomide. It functions by recruiting the CRBN protein. This compound can be linked to an IRAK4 protein ligand using a linker to create PROTAC IRAK4 degrader-1 (HY-129966).
- Thalidomide-based Cereblon ligand
- Used in the recruitment of CRBN protein
- Can be connected to other ligands via a linker to form PROTACs
Medchemexpress LLC Thalidomide-piperazine 5-fluoride hydrochloride | 2222114-23-8 | MFCD32203462 | 98.9% | 396.80 g/mol | C17H18ClFN4O4 | 1 G
Thalidomide-piperazine 5-fluoride hydrochloride is a thalidomide-derived cereblon (CRBN) ligand supplied as a hydrochloride salt for use in PROTAC synthesis and related cereblon-targeted chemical biology research. It is intended for research use and is provided with documented purity and stability data for handling and storage.
- Thalidomide-based cereblon ligand for PROTAC synthesis.
- Hydrochloride salt form for improved handling and solubility.
- High purity suitable for synthetic and analytical workflows.
- Documented stability under cold storage conditions.
- Provided in a small-scale research package for medicinal chemistry.
Medchemexpress LLC Thalidomide 5-fluoride | 835616-61-0 | MFCD30188075 | 100.0% | 276.22 g/mol | C13H9FN2O4 | 10 G
Thalidomide 5-fluoride is a thalidomide-derived cereblon ligand used as a building block in PROTAC degraders and other bifunctional molecules. It is supplied as a high-purity solid reagent intended for research and chemical biology applications.
- High purity solid (99.96%).
- Molecular weight 276.22 g/mol.
- Molecular formula C13H9FN2O4.
- Available in laboratory pack sizes, including 10 G.
- Storage: powder at -20°C for long-term, 4°C for shorter term; in solvent store at -80°C.
Apexbio Technology LLC Brucine 20mg
N1490 is a small-molecule inhibitor designed for biomedical research It exerts its effects by selectively targeting and modulating specific intracellular signaling pathways implicated in disease progression N1490 has been explored in cellular assays for its ability to interfere with relevant molecular interactions resulting in altered downstream signaling events This compound serves as a valuable tool for investigating cellular mechanisms regulated by these pathways and may facilitate the discovery of novel therapeutic strategies in areas such as oncology immunology or metabolic research