Lactams
Medchemexpress LLC Tetrazine-tagged thalidomide | 2087490-42-2 | 98.6% | 571.58 g/mol | C29H29N7O6 | 100 MG
Tz-Thalidomide is a tetrazine-tagged derivative of thalidomide used in bioorthogonal click-chemistry and as an E3 ligase ligand for biochemical research. It contains a reactive tetrazine group for rapid conjugation via inverse electron demand Diels-Alder reactions and has been characterized for binding to BRD4.
- Tetrazine moiety enables rapid inverse electron demand Diels-Alder (iEDDA) click reactions.
- Functions as an E3 ligase ligand for targeted protein interaction studies.
- Documented binding affinity to BRD4 in biochemical assays.
- High purity suitable for research applications.
- Available as a solid and as a 10 mM solution in DMSO for experimental flexibility.
Medchemexpress LLC N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide TFA salt | 1799711-25-3 | MFCD31560484 | 99.9% | 516.42 g·mol⁻¹ | C21H23F3N4O8 | 2 G
Thalidomide-O-amido-C4-NH2 TFA is a thalidomide-derived cereblon ligand-linker conjugate provided as the trifluoroacetate (TFA) salt for use in PROTAC design and other chemical biology applications. It is supplied as a white to off-white solid with high analytical purity and a molecular weight of 516.42 g·mol⁻¹.
- Thalidomide-derived cereblon ligand-linker conjugate.
- Provided as the trifluoroacetate (TFA) salt.
- High purity by LCMS (reported 99.92%).
- White to off-white solid appearance.
- Molecular formula C21H23F3N4O8; molecular weight 516.42 g·mol⁻¹.
- Intended for research use only; not for human or diagnostic use.
Medchemexpress LLC CD3 epsilon Human 100ug
Recombinant human CD3 epsilon protein supplied as a lyophilized powder, expressed in HEK293 cells and carrying a C-terminal 6xHis tag. The protein is intended for T-cell signaling research, assay development, and biochemical characterization; it offers high purity and low endotoxin to support sensitive in vitro and cell-based assays.
- Lyophilized powder for convenient storage and transport.
- Expressed in HEK293 cells for human-like post-translational modifications.
- C-terminal 6xHis tag facilitates purification and detection.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Endotoxin level below 1 EU/μg, suitable for sensitive assays.
- Available in 10 μg, 50 μg, 100 μg, and 500 μg sizes.
- Recommended reconstitution at ≥100 μg/mL; refer to lot-specific COA for buffer details.
Medchemexpress LLC Tetrazine-tagged thalidomide | 2087490-42-2 | 98.6% | 571.58 g/mol | C29H29N7O6 | 25 MG
Tz-Thalidomide is a tetrazine-tagged derivative of thalidomide designed as a chemical probe and building block for targeted protein degradation and molecular-glue research. Supplied as a research reagent for laboratory use only (not for human or clinical applications).
- Tetrazine-tagged thalidomide derivative for click chemistry (iEDDA).
- Suitable as a building block in PROTAC and molecular-glue studies.
- High purity, typically 98.6%.
- Available in small research pack sizes, including 25 mg.
- Molecular formula C29H29N7O6; molecular weight 571.58 g/mol.
Medchemexpress LLC CD23/Fc epsilon RII 10ug
CD23/Fc epsilon RII Protein a low-affinity receptor for IgE and CR2/CD21 regulates IgE production and B cell differentiation On B cells it initiates IgE-dependent antigen uptake and presentation to T cells On macrophages IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding CD23/Fc epsilon RII Protein Mouse (HEK293 His) is the recombinant mouse-derived CD23/Fc epsilon RII protein expressed by HEK293 with N-His labeled tag
Medchemexpress LLC Tetrazine-tagged thalidomide | 2087490-42-2 | MFCD34706062 | 98.6% | 571.58 g/mol | C29H29N7O6 | 5 MG
Tz-Thalidomide is a tetrazine-tagged derivative of thalidomide developed as an E3 ligase ligand and click-chemistry reagent. It is designed to undergo inverse electron-demand Diels-Alder (iEDDA) reactions with strained alkenes and has demonstrated binding activity to BRD4 in biochemical assays.
- Tetrazine functional group for rapid iEDDA click reactions with TCO-modified partners.
- Reported BRD4 binding (IC50: 46.25 μM for BRD4-1; 62.55 μM for BRD4-2).
- High purity suitable for research applications (98.6%).
- Solid, pink to red appearance for easy handling.
- Soluble in DMSO (~50 mg/mL), facilitating stock solution preparation.
- Storage conditions provided to support stability in powder and solution.
eMolecules 50607-30-2 | 2,4-Piperidinedione | Combi-Blocks | MFCD08704814 | 113.116 | C5H7NO2 | 98.000 | O=C1CCNC(=O)C1 | 25g | 205391986
2,4-Piperidinedione | Combi-Blocks | 50607-30-2 | MFCD08704814 | 113.116 | C5H7NO2 | 98.000 | O=C1CCNC(=O)C1 | 25g | 205391986