Lactams
![Medchemexpress LLC Tert-butyl 4-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]piperazine-1-carboxylate | 2222114-64-7 | MFCD32705088 | 98.8% | C22H26N4O6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259258.png-250.jpg)
Medchemexpress LLC Tert-butyl 4-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]piperazine-1-carboxylate | 2222114-64-7 | MFCD32705088 | 98.8% | C22H26N4O6 | 10MG
Thalidomide-piperazine-Boc is a Boc-protected piperazine derivative of thalidomide used as a synthetic intermediate for assembling E3 ligase ligand-linker conjugates such as PROTACs. It is supplied as a high-purity research reagent with defined solubility and storage recommendations.
- High purity (98.8%).
- Boc-protected piperazine for linker attachment.
- Soluble in DMSO (~41.7 mg/mL) with ultrasonic assistance.
- Powder stable at -20°C for long-term storage; solvent storage recommendations apply.
- Intended for research use only.
Medchemexpress LLC Thalidomide-PEG5-NH2 hydrochloride | 2703775-06-6 | MFCD34550803 | 95.2% | 529.97 g·mol⁻¹ | C23H32ClN3O9 | 5 MG
Thalidomide-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon (CRBN) binding moiety with a PEG5 amine linker, supplied as the hydrochloride salt. It is intended for use in PROTAC design and chemical biology research involving CRBN-mediated protein degradation.
- Cereblon-binding thalidomide-derived ligand.
- PEG5 amine linker provides a flexible spacer for conjugation.
- Hydrochloride salt improves solubility and handling.
- Characterized by CAS 2703775-06-6 and molecular weight 529.97 g·mol⁻¹.
- Purity approximately 95.2% by LCMS.
- Intended for research use in targeted protein degradation studies.
Medchemexpress LLC Thalidomide O-amido C3-COOH | 2308035-51-8 | 98.4% | 417.37 g/mol | C19H19N3O8 | 50 MG
Thalidomide O-amido C3-COOH is a synthesized E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon-binding moiety with a short linker terminating in a carboxylic acid. It is provided as a research-grade chemical for use in PROTAC design and related chemical biology applications.
- Contains thalidomide-based cereblon ligand
- Three-carbon (C3) linker with terminal carboxylic acid
- Molecular formula C19H19N3O8; molecular weight 417.37 g/mol
- Purity 98.4% (research grade)
- Supplied as a white solid suitable for chemical synthesis
- Intended for research use only, not for human or clinical use
Medchemexpress LLC Thalidomide-NH-PEG2-COOH | 2412056-45-0 | 99.0% | 433.41 | 25 MG
Thalidomide-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Thalidomide based cereblon ligand and a linker that is utilized in PROTAC technology. This product is intended for research use only.
- Synthesized E3 ligase ligand-linker conjugate
- Utilizes PROTAC technology
- Incorporates Thalidomide based cereblon ligand
- Intended for research use only
Medchemexpress LLC 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | 26166-92-7 | MFCD30188073 | 98.4% | 337.13 | C13H9BrN2O4 | 100 MG
Thalidomide-5-Br is a brominated thalidomide derivative supplied for research use in studies of inflammation, tumor biology, and neurology. It is provided as a solid research reagent; consult lot-specific documentation for analytical details.
- Contains a bromodomain; used as a tool compound in biochemical and pharmacological research.
- Reported purity approximately 98% (see product documentation for lot-specific certificate of analysis).
- Solid, off-white to gray appearance suitable for analytical and synthetic applications.
- Storage recommendations: room temperature for shipping; in solution store at -80°C (2 years) or -20°C (1 year).
- Available in multiple pack sizes including 100 mg.
eMolecules 2743434-24-2 | Medchem Express | Thalidomide-5-PEG4-NH2 (hydrochloride) | 5mg | 778475789 | HY-138785A | 485.92 | C21H28ClN3O8
AstaTech | 1-(4-BROMOPHENYL)PIPERAZINE | 1g | 302795728 | 28586 | 97.000 | 66698-28-0 | MFCD00130198 | 241.132 | C10H13BrN2
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