Lactams
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eMolecules 2,4-Piperidinedione | Combi-Blocks | 50607-30-2 | MFCD08704814 | 113.116 | C5H7NO2 | 98.000 | O=C1CCNC(=O)C1 | 25g | 205391986
2,4-Piperidinedione | Combi-Blocks | 50607-30-2 | MFCD08704814 | 113.116 | C5H7NO2 | 98.000 | O=C1CCNC(=O)C1 | 25g | 205391986
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Medchemexpress LLC Thalidomide-5-CH2-NH2 hydrochloride | 1010100-22-7 | MFCD32666042 | 98.6% | 323.73 | C14H14ClN3O4 | 50 MG
Thalidomide-5-CH2-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand used as an E3 ligase recruiting moiety in PROTAC design and targeted protein degradation research. Supplied as a solid with high purity, it serves as a linker-compatible building block for medicinal chemistry and chemical biology applications.
- High purity suitable for research.
- Solid form, easy to handle and store.
- Compatible with linker conjugation for PROTAC synthesis.
- Facilitates CRBN-mediated target recruitment.
- Available in multiple small pack sizes for synthesis workflows.
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Medchemexpress LLC Thalidomide-1-me,4-oh | 2244568-06-5 | ≥98.0% | 288.26 g·mol-1 | C14H12N2O5 | 100 MG
Thalidomide-1-Me,4-OH is a thalidomide analogue bearing a 4-hydroxy substituent and an N-1 methyl group. It serves as a cereblon/E3 ligase ligand scaffold for research into ubiquitin-mediated proteolysis and is supplied as a solid research reagent.
- Small-molecule cereblon/E3 ligase ligand used in biochemical and cell-based assays
- High purity suitable for research applications
- Powder form with defined storage recommendations for long-term stability
- Includes chemical identifiers for traceability, including CAS and molecular formula
- Applicable for studies of targeted protein degradation and ligand design
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