Lactams
Medchemexpress LLC Thalidomide-NH-PEG2-COOH | 2412056-45-0 | 99.0% | 433.41 | 100 MG
Thalidomide-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate designed for PROTAC technology. It incorporates a Thalidomide-based cereblon ligand and is intended for research use only.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Thalidomide-based cereblon ligand
- Utilized in PROTAC technology
- High purity: 99.0%
- Molecular weight: 433.41
- Molecular formula: C20H23N3O8
- Appearance: Light green to green solid
- Recommended storage: -20°C, sealed, away from moisture and light
- For research use only
Medchemexpress LLC Thalidomide-propargyne-PEG3-COOH | 2797649-54-6 | MFCD34473293 | 98.0% | 472.45 g/mol | C23H24N2O9 | 5 MG
Thalidomide-propargyne-PEG3-COOH is a thalidomide-based E3 ligase ligand-linker conjugate with a propargyl (alkynyl) handle and a PEG3 linker terminating in a carboxylic acid. Designed as a building block for PROTAC assembly and related chemical biology work, it is compatible with click chemistry and standard amide-coupling reactions. CAS 2797649-54-6; formula C23H24N2O9; MW 472.45; typical purity ~98%.
- Contains a propargyl (alkynyl) handle for CuAAC click chemistry.
- Includes a PEG3 linker terminating in a carboxylic acid for conjugation.
- Acts as a cereblon (CRBN) E3 ligase ligand for PROTAC design.
- Suitable for amide coupling and linker attachment.
- Supplied as a solid with high purity for research use.
Medchemexpress LLC VH 101 phenol-alkylC4-amine dihydrochloride | 2564467-03-2 | >95.0% | 676.67 g/mol | C30H44Cl2FN5O5S | 5 MG
VH 101 phenol-alkylC4-amine dihydrochloride is a functionalized von Hippel-Lindau (VHL) E3 ligase ligand supplied as the dihydrochloride salt. It is designed as a building block for PROTAC (proteolysis-targeting chimera) synthesis and degrader design, offering a linker-equipped ligand with a terminal amine for conjugation and medicinal chemistry applications.
- Functionalized VHL ligand for PROTAC synthesis.
- Dihydrochloride salt for improved stability and handling.
- Terminal amine compatible with common coupling chemistries.
- Alkyl C4 linker suitable for assembling bifunctional degraders.
- Available in small milligram quantities for medicinal chemistry research.
Medchemexpress LLC Thalidomide-5-PEG4-NH2 hydrochloride | 2743434-24-2 | 95.2% | 485.92 g/mol | C21H28ClN3O8 | 5 MG
Thalidomide-5-PEG4-NH2 hydrochloride is a thalidomide-derived E3 ligase ligand-linker conjugate that combines a cereblon-binding thalidomide moiety with a four-unit PEG linker. It is intended as a research reagent for PROTAC design and targeted protein degradation studies and is supplied as a light yellow to yellow oil with reported high purity.
- Designed as an E3 ligase ligand-linker conjugate for PROTAC synthesis.
- Contains a cereblon-binding thalidomide moiety with a PEG4 linker for linker flexibility.
- High reported purity suitable for research applications (95.2%).
- Soluble in DMSO at 100 mg/mL; ultrasonic agitation recommended.
- Light yellow to yellow oil; easy to handle in synthetic workflows.
- Store sealed away from moisture; recommended storage at -20°C (in solvent: -80°C for long term).
eMolecules 28562-53-0 | 4-Acetoxy-2-azetidinone | Ambeed | MFCD00010593 | 129.115 | C5H7NO3 | 97.000 | CC(=O)OC1CC(=O)N1 | 25g | 552638488
4-Acetoxy-2-azetidinone | Ambeed | 28562-53-0 | MFCD00010593 | 129.115 | C5H7NO3 | 97.000 | CC(=O)OC1CC(=O)N1 | 25g | 552638488
Medchemexpress LLC Thalidomide-4-o-c12-nh2 hydrochloride | 95.6% | 494.02 | 25 MG
Thalidomide-4-O-C12-NH2 hydrochloride is a thalidomide-based cereblon ligand utilized for the recruitment of CRBN protein. It can be linked to a protein ligand via a linker to form PROTACs.
- Thalidomide-based cereblon ligand
- Utilized for recruitment of CRBN protein
- Can be linked to a protein ligand via a linker to form PROTACs
- Target: Cereblon
Medchemexpress LLC Thalidomide-4-O-C6-NH2 hydrochloride | 2245697-88-3 | 98.5% | 409.86 | C19H24ClN3O5 | 5 MG
Thalidomide-4-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate supplied as the hydrochloride salt for research use. It is used as a building block in PROTAC dTAG-13, a degrader of FKBP12F36V and BET proteins, and is provided with supporting analytical data and handling documentation.
- Provided as the hydrochloride salt suitable for synthetic applications.
- High purity (98.5% by HPLC) with supporting analytical data.
- Analytical files include data sheet, COA, H NMR, and LCMS.
- Available in multiple pack sizes from milligrams to grams.
- Intended for research use only; not for human or therapeutic use.
Medchemexpress LLC Aztreonam (Standard) | 78110-38-0 | 99.6% | 50 MG
Aztreonam (Standard) is an analytical standard intended for research and analytical applications. It is a synthetic monocyclic beta-lactam antibiotic, also known as SQ-26,776, which demonstrates a high affinity for penicillin-binding protein 3 (PBP-3). This product is suitable for qualitative, quantitative, and methodological research experiments, including HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Synthetic monocyclic beta-lactam antibiotic
- High affinity for penicillin-binding protein 3 (PBP-3)
- Suitable for HPLC, GC, and MS research experiments