Oxazinanes
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.4% | 100 MG
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative that can be used for bronchiectasis research.
- Can be used for bronchiectasis research
- Exhibits cytotoxicity against human A375 cells (IC50: 39 μM) and human MRC5 cells (IC50: 47 μM)
- Recommended storage temperature for powder is -20°C for 3 years and 4°C for 2 years
- Recommended storage temperature for in solvent is -80°C for 6 months and -20°C for 1 month
Medchemexpress LLC CN128 hydrochloride | 1335282-05-7 | 98.2% | 250 MG
CN128 hydrochloride (CN328) is an orally active and selective iron chelator primarily used in the research of β-thalassemia. It demonstrates high selectivity for iron(III) over other metals and has been shown to lack genetic toxicity.
- Orally active and selective iron chelator
- Used for research of β-thalassemia
- Exhibits high selectivity for iron(III) over other metals
- Lacks genetic toxicity
- Demonstrates good oral bioavailability (82.6%) in rats
- Well-tolerated in rats with no mortality at higher dose levels
- Shows good iron scavenging efficacy in rats
Medchemexpress LLC VU591 hydrochloride | 1315380-70-1 | 98.9% | 404.76 | 1 ML
VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. It can be used for neurological research with HY-108585A (the equivalent of VU591 hydrochloride).
- Potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor
- IC50 of 0.24 μM
- Suitable for neurological research
- Binds serum protein
- High metabolic stability
- Shows antidepressive effect in male ICR mice
Medchemexpress LLC Pyrithioxin dihydrochloride | 10049-83-9 | 98.0% | 500 MG
Pyrithioxin (Pyritinol) dihydrochloride is the dihydrochloride salt of Pyrithioxin. Pyrithioxin (Pyritinol) is an orally active neurodynamic compound. Pyrithioxin can promote the metabolism of glucose and amino acids, increase carotid blood flow and improve cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor and neuroprotective effect. Pyrithioxin can be used for the researches of cancer, inflammation, immunology, metabolic and neurological disease such as cerebral infarct, epilepsy, fibrosarcomas and rheumatoid polyarthritis.
- Promotes metabolism of glucose and amino acids
- Increases carotid blood flow and improves cerebral blood flow
- Exhibits anti-inflammation effects
- Exhibits anti-tumor effects
- Provides neuroprotective effects
TARGETMOL CHEMICALS INC DROBULINE HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Drobuline hydrochloride is an anti-arrhythmic agent with cardiac depressant activity. purity: 98%
TARGETMOL CHEMICALS INC CHK1-IN-4 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1). CHK1-IN-4 hydrochloride potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 hydrochloride has anti-tumor activity.
Cayman Chemical SRT 1720 hydrochloride
A selective small molecule activator of SIRT1 that is 1,000-fold more potent than resveratrol; improves insulin sensitivity, lowers plasma, glucose and increases mitochondrial capacity in diet-induced obese and diabetic leptin-deficient ob/ob mice after one week of treatment with an oral dose of 100 mg/kg once daily.
Medchemexpress LLC 2,5(1H,6H)-quinolinedione, 7,8-dihydro | 15450-69-8 | MFCD00766821 | 99.9% | 163.17 g/mol | C9H9NO2 | 10 G
7,8-Dihydro-2,5(1H,6H)-quinolinedione (compound SF32) is a research-grade small molecule described in literature as a positive inotropic agent. It is supplied as a solid with high analytical purity and intended for laboratory research applications; refer to the manufacturer documentation and certificate of analysis for handling, storage, and stability details.
- High reported purity: 99.86%.
- Solid form; appearance light brown to light yellow.
- Stable under recommended storage: powder -20°C (3 years) or 4°C (2 years).
- Solvent storage guidance: -80°C for 6 months, -20°C for 1 month.
- Suitable for in vitro research as a positive inotropic agent.
- Available in multiple pack sizes for laboratory use.
- Supplied with a certificate of analysis for quality verification.
Medchemexpress LLC Quizartinib dihydrochloride | 1132827-21-4 | 99.8% | C29H34Cl2N6O4S | 100 MG
Quizartinib dihydrochloride (AC220 dihydrochloride) is the dihydrochloride salt form of Quizartinib. This compound is an orally active, highly selective, and potent second-generation type II FLT3 tyrosine kinase inhibitor, characterized by a Kd of 1.6 nM. It is intended for research use only.
- Highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor
- Effectively inhibits wild-type FLT3 and FLT3-ITD autophosphorylation
- Can be utilized in PROTAC technology to create FLT3 degraders
- Capable of inducing apoptosis
- Provides high purity for reliable research results
- Presents as a white to off-white solid
Medchemexpress LLC Tebanicline dihydrochloride | 209326-19-2 | 99.5% | C9H13Cl3N2O | 1 ML
Tebanicline dihydrochloride is a potent, orally effective analgesic that modulates neuronal nicotinic acetylcholine receptors (nAChRs). It exhibits high selectivity for neuronal nAChRs, acting as an agonist, and effectively inhibits cytisine binding to α4β2 neuronal nAChRs. This product is investigated for its potential in treating various types of pain and for its anxiolytic-like properties.
- Potent and orally effective analgesic.
- Highly selective for neuronal nAChRs.
- Shows efficacy in models of acute, persistent, chemical, and neuropathic pain.
- Investigated for anxiolytic-like activity.
Medchemexpress LLC 3-butenoic acid | 625-38-7 | MFCD00002782 | 98.6% | 86.09 g/mol | C4H6O2 | 1 G
3-Butenoic acid (vinylacetic acid) is a small-molecule carboxylic acid used as a synthetic building block and intermediate in organic and medicinal chemistry research. It is supplied as a high-purity reagent for research and formulation applications.
- Small-molecule carboxylic acid used as a synthetic building block and intermediate.
- CAS number 625-38-7.
- Chemical formula C4H6O2; molecular weight 86.09 g/mol.
- Purity 98.6%.
- Soluble in DMSO at 100 mg/mL; suitable for in vitro formulation and certain in vivo formulations (e.g., ≥2.5 mg/mL in 10% DMSO/SBE-β-CD or 10% DMSO/corn oil).
- Recommended storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Available in milligram to kilogram pack sizes for research use.
TARGETMOL CHEMICALS INC ELSIBUCOL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Elsibucol (AGI 1096) is a VCAM1 inhibitor for the study of organ transplant rejection.Elsibucol is a metabolically stable propanol derivative with antioxidant anti-inflammatory and anti-proliferative properties. It lowers blood cholesterol levels and reduces oxidative stress and inflammatory responses in injured arteries thereby inhibiting atherosclerosis and protecting endothelial healing after arterial injury. purity: 98%
Cayman Chemical CP 24 879 hydrochloride
A Δ5/Δ6 desaturase inhibitor; reduces liver arachidonate content by ~50% in mice at 3 mg/kg; increases mead acid content and inhibits leukotriene C4 synthesis in murine mastocytoma cells at 5 µM
TARGETMOL CHEMICALS INC CX-6258 HYDROCHLORIDE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective orally efficacious Pim1/2/3 kinase inhibitor (IC50 5/25/16 nM). purity: 98%
Medchemexpress LLC Clobenpropit dihydrobromide | 145231-35-2 | MFCD00467655 | 99.8% | 470.65 g/mol | C14H19Br2ClN4S | 50 MG
Clobenpropit dihydrobromide is a high-purity research chemical used as a potent histamine H3 receptor antagonist/inverse agonist and a partial H4 receptor agonist. Supplied as a white to off-white solid, it is intended for pharmacology and neuroscience studies to investigate histaminergic signaling and receptor pharmacology.
- High reported purity (99.76%).
- Molecular weight 470.65 g/mol; formula C14H19Br2ClN4S.
- White to off-white solid form suitable for in vitro and in vivo research.
- Recommended storage: 4°C sealed; in solvent -80°C up to 6 months.
- Potent nanomolar activity at histamine H3 and partial activity at H4; reported off-target binding to 5-HT3 and α2 adrenoceptors.