Oxazinanes

Apexbio Technology LLC Midodrine (hydrochloride) 43218-56-0 250mg

Midodrine hydrochloride (CAS 43218-56-0) is a prodrug that is metabolized to desglymidodrine a selective agonist of 1-adrenergic receptors It exhibits binding affinities (Ki) of 2 M 6 9 M and 1 7 M for the 1A 1B and 1D receptor subtypes respectively Activation of these receptors mediates vasoconstriction in arteriolar and venous smooth muscle resulting in increased vascular tone and blood pressure Preclinical studies have also shown that central administration of midodrine affects thermoregulation and locomotor activity in animal models Research applications include investigation of adrenergic signaling cardiovascular regulation and combination therapy for refractory ascites

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Apexbio Technology LLC W-13 hydrochloride 88519-57-7 1mg

W-13 hydrochloride (CAS 88519-57-7) is a small molecule inhibitor that acts as an antagonist of calmodulin thereby modulating calmodulin-dependent signaling pathways and influencing intracellular calcium homeostasis Studies have demonstrated that W-13 hydrochloride suppresses the proliferation of human breast cancer cells resistant to tamoxifen indicating its utility in investigating mechanisms underlying cancer drug resistance This compound is widely employed in biomedical research to dissect calmodulin-mediated signaling and to explore pathways involved in the adaptive responses of tumor cells

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Cayman Chemical MethylLNIO hydrochloride

A competitive NOS inhibitor; more potent inhibitor of nNOS (Ki = 3.0 µM) than eNOS (Ki = 10.0 µM) or iNOS (Ki = 9.5 µM)

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

TARGETMOL CHEMICALS INC PF-543 HYDROCHLORIDE 10MG

Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform. purity: 99%

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Cayman Chemical Oxybutynind10 hydrochloride

An internal standard for the quantification of oxybutynin by GC- or LC-MS

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

TARGETMOL CHEMICALS INC L-778123 HYDROCHLORIDE 25MG

Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. The L-778123 hydrochloride is an inhibitor of FPTase (IC50 2 nM) and GGPTase-I (IC50 98 nM) in enzyme inhibition determination. purity: 98%

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

TARGETMOL CHEMICALS INC Bendamustine hydrochloride

Also available in 1 mL, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Bendamustine hydrochloride (EP-3101) (IC50 of 50 uM) is an alkylating agent associated with DNA damage. Purity 98.03%

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC 1H-Pyrrolo[2,3-b]pyridine, 2,3-dihydro- | 10592-27-5 | 99.96% | 120.16 | 10 G

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

2,3-Dihydro-7-azaindole (7-Azaindoline) is a biochemical reagent. It can be used as a biological material or organic compound for life science related research.

• Can be used as a biological material
• Can be used as an organic compound
• Suitable for life science related research

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC 1H-Pyrrolo[2,3-b]pyridine, 2,3-dihydro- | 10592-27-5 | 99.96% | 120.16 | 50 G

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

2,3-Dihydro-7-azaindole (7-Azaindoline) is a biochemical reagent that can be utilized as a biological material or an organic compound for research in life sciences. This product is intended for research use only and is not sold to patients.

• Can be used as a biochemical reagent.
• Suitable for life science-related research as a biological material or organic compound.
• Available with a purity of 99.96%.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC Clobenpropit dihydrobromide | 145231-35-2 | MFCD00467655 | 99.8% | 470.65 g/mol | C14H19Br2ClN4S | 25 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Clobenpropit dihydrobromide is a research-grade histamine H3 receptor antagonist and H4 receptor agonist supplied as the dihydrobromide salt. Provided as a high-purity solid, it is used in pharmacology and neuroscience research to probe histaminergic signaling, receptor pharmacology, and cellular responses in vitro. Consult the product datasheet and SDS for handling, storage, and safety information.

• High-purity dihydrobromide salt suitable for research applications.
• Relevant for histamine receptor pharmacology and signaling studies.
• Stable solid form for accurate dosing in in vitro assays.
• Compatible with standard solvent systems for reconstitution.
• Offered in small pack sizes for laboratory-scale experiments.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Cayman Chemical EthylLNIO hydrochloride

A modestly selective NOS inhibitor with Ki values for inhibition of nNOS, eNOS, and iNOS of 5.3, 18, and 12 µM, respectively; however, does not show biologically significant selectivity for nNOS over eNOS, and instead favors iNOS (Ki/Km = 3.79, 5, and 0.96 µM, respectively)

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ 1577233-70-5 | 3-[(Tributylstannyl)methoxy]-1-propanamine | Synthonix - Stock | MFCD28579830 | 378.188 | C16H37NOSn | 98.000 | CCCC[Sn](CCCC)(CCCC)COCCCN | 1g | 525924099

3-[(Tributylstannyl)methoxy]-1-propanamine | Synthonix - Stock | 1577233-70-5 | MFCD28579830 | 378.188 | C16H37NOSn | 98.000 | CCCC[Sn](CCCC)(CCCC)COCCCN | 1g | 525924099

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

TARGETMOL CHEMICALS INC REGORAFENIB HYDROCHLORID 100MG

Also available in 5 mg 10 mg 25 mg 50 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activitypurity: 100%

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Selleck Chemical LLC Delapril Hydrochloride

Delapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril which is a lipophilic non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Apexbio Technology LLC AT7519 Hydrochloride 902135-91-5 10mM (in 1mL DMSO)

AT7519 Hydrochloride (CAS 902135-91-5) is a small-molecule inhibitor of cyclin-dependent kinases (CDKs) which are critical regulators of cell proliferation division and apoptosis in eukaryotic cells By targeting multiple CDKs including CDK1 and CDK2 AT7519 induces cell cycle arrest and apoptosis in various human tumor cell lines demonstrating inhibitory activity with IC50 values ranging from 40 to 940 nmol/L In preclinical studies it suppressed tumor growth in xenograft models and promoted tumor cell apoptosis AT7519 is under clinical evaluation for the treatment of refractory solid tumors supporting its utility in cancer research and drug development

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More