Piperidines
Apexbio Technology LLC Hoechst 33342/PI Double Staining Kit 500T
Hoechst 33342 PI Double Staining Kit is a fluorescence-based assay kit designed to distinguish apoptosis and necrosis in cell populations The kit utilizes two fluorescent probes Hoechst 33342 and propidium iodide (PI) to assess plasma membrane integrity and nuclear morphology Hoechst 33342 penetrates live cells and binds to DNA producing blue fluorescence with intensity increasing upon apoptotic chromatin condensation PI is impermeable to intact cell membranes and selectively labels necrotic cells with red fluorescence Compared to single-stain apoptosis assays this dual-stain approach enables simultaneous detection of viable apoptotic and necrotic cells Based on these properties Hoechst 33342 PI Double Staining Kit is applicable in pharmacological evaluation and cytotoxicity studies
Medchemexpress LLC PI-55 | 1122579-42-3 | 98.9% | C13H13N5O | 1 ML
PI-55 is a specific cytokinin receptor inhibitor that is structurally related to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3. PI-55 also inhibits cytokinin-induced haustorium formation and increases parasite aggressiveness.
- Specific cytokinin receptor inhibitor
- Competitively inhibits BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3
- Inhibits cytokinin-induced haustorium formation
- Increases parasite aggressiveness
- Causes incomplete blocking of early haustorial structure development at high concentrations (10 μM and 100 μM)
- Reduces the overall aggressiveness of P. ramosa when applied with BAP
![Medchemexpress LLC 2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl-. | 874755-26-7 | 98.3% | 389.41 g·mol⁻¹ | C21H19N5O3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000263510.png-250.jpg)
Medchemexpress LLC 2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl-. | 874755-26-7 | 98.3% | 389.41 g·mol⁻¹ | C21H19N5O3 | 5 MG
GPR40/FFAR1 modulator 1 is a small-molecule agonist and allosteric modulator of the Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1). It is supplied for research use to probe receptor pharmacology, ligand modulation, and downstream signaling in cellular assays. Supplied as an off-white to light-yellow solid with characterized purity and molecular properties.
- Acts as an agonist and allosteric modulator of GPR40/FFAR1.
- Suitable for receptor pharmacology and signaling studies.
- Provided as a solid and as a 10 mM solution in DMSO.
- High purity (≈98.3%) for consistent experimental results.
- Molecular formula C21H19N5O3 and molecular weight 389.41 g·mol⁻¹.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC HY-105545A 10mg Medchemexpress, Levetimide CAS:21888-99-3 Purity:>98%
Medchemexpress, HY-105545A 10mg Levetimide CAS:21888-99-3 Levetimide is a potent and stereoselective inhibitor of [ 3 H](+)pentazocine binding, with a K i of 2.2 nM [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-114926 10mg Medchemexpress, KT185 CAS:1472640-86-0 Purity:>98%
Medchemexpress, HY-114926 10mg KT185 CAS:1472640-86-0 KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-12059 5mg Medchemexpress, AT7867 CAS:857531-00-1 Purity:>98%
Medchemexpress, HY-12059 5mg AT7867 CAS:857531-00-1 AT7867 is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC 2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4- | 874755-26-7 | 98.3% | 389.41 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000438893-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4- | 874755-26-7 | 98.3% | 389.41 | 100 MG
GPR40/FFAR1 modulator 1 is an agonist and an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1).
- Acts as an agonist for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1)
- Functions as an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1)
Medchemexpress LLC HY-105545 50mg Medchemexpress, Dexetimide CAS:21888-98-2 Purity:>98%
Medchemexpress, HY-105545 50mg Dexetimide CAS:21888-98-2 Dexetimide ((+)-Benzetimide) is a high-affinity muscarinic receptor antagonist and a potent and persistent anticholinergic agent used to treat neuroleptic-induced parkinsonism. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC SERCA2a activator 1 (compound A) | 2139330-34-8 | 99.7% | 551.66 g/mol | C32H29N3O4S | 50MG
SERCA2a activator 1 is a small-molecule activator of the sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a (SERCA2a). It reduces phospholamban-mediated inhibition and can enhance cardiac contractile and relaxation responses in preclinical models. The compound is supplied for research use as a high-purity solid and is also available as a DMSO solution for assay use.
- Activates SERCA2a to improve calcium handling in cardiac models.
- High purity: 99.7%.
- Molecular weight: 551.66 g/mol.
- Chemical formula: C32H29N3O4S.
- Physical form: light yellow to yellow solid powder.
- Available as powder and as a 10 mM solution in DMSO.
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months).
eMolecules 1936529-65-5 | Medchem Express | YKL-05-099 | 5mg | 446256520 | HY-101147 | MFCD31382123 | 600.12 | C32H34ClN7O3
Ambeed | 2-(Cyclopropanecarboxamido)-4567-tetrahydrobenzo[b]thiophene-3-carboxamide | 5mg | 534568377 | A499106 | 329221-38-7 | MFCD00785286 | 264.340 | C13H16N2O2S
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eMolecules 1204329-34-9 | Medchem Express | BI-9627 | 5mg | 455326299 | HY-18071 | MFCD25976925 | 356.349 | C16H19F3N4O2
Ambeed | 4-Bromo-2-fluoro-3-methylpyridine | 100mg | 521423755 | A215661 | 128071-79-4 | MFCD09839278 | 190.015 | C6H5BrFN
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Medchemexpress LLC Pi-Methylimidazoleacetic acid hydrochloride | 1071661-55-6 | 99.01% | 176.60 | 1 ML
Pi-Methylimidazoleacetic acid hydrochloride is a potential neurotoxin and an endogenous metabolite. It is for research use only and not sold to patients.
- Endogenous metabolite
- Potential neurotoxin
eMolecules 1422252-46-7 | Medchem Express | BI-9627 (hydrochloride) | 5mg | 624169625 | HY-18071A | MFCD30182310 | 392.81 | C16H20ClF3N4O2
ChemScene | 5-Bromo-1H-indazol-4-amine | 100mg | 632324794 | CS-0160659 | 1891120-48-1 | MFCD30721204 | 212.050 | C7H6BrN3
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Medchemexpress LLC 1-(Chlorocarbonyl)piperidine-d10 | 1219803-31-2 | 98.2% | 157.66 | 1 MG
1-(Chlorocarbonyl)piperidine-d10 is the deuterium labeled 1-(Chlorocarbonyl)piperidine. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
![Medchemexpress LLC 5'-benzyl-1'-butyl-N-(naphthalen-2-ylsulfonyl)-6'-oxo-1',6'-dihydro-[2,3'-bipyridine]-4-carboxamide | 2139330-34-8 | 99.5% | 551.66 g·mol⁻¹ | C32H29N3O4S | 5MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235385.png-250.jpg)
Medchemexpress LLC 5'-benzyl-1'-butyl-N-(naphthalen-2-ylsulfonyl)-6'-oxo-1',6'-dihydro-[2,3'-bipyridine]-4-carboxamide | 2139330-34-8 | 99.5% | 551.66 g·mol⁻¹ | C32H29N3O4S | 5MG
SERCA2a activator 1 is a small-molecule activator of the sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a (SERCA2a) used in preclinical cardiovascular research to attenuate phospholamban inhibition and enhance cardiac contractile function. Supplied for research use only.
- Activates SERCA2a and attenuates phospholamban inhibition.
- Used to enhance systolic and diastolic cardiac function in research models.
- Molecular formula C32H29N3O4S.
- Molecular weight 551.66 g·mol⁻¹.
- Available in milligram quantities suitable for in vitro and in vivo studies.
- Supplied for research use only; not for human or veterinary use.